Protein: CSN4
COP9 signalosome complex subunit 4 (Dch4) (Signalosome subunit 4)

Gene: CSN4
Organism: Drosophila melanogaster
Interactions: 49
UniProt ID: Q9V345

Gene Ontology (top 5):
GO:0000338 - protein deneddylation
GO:0000976 - transcription cis-regulatory region binding
GO:0001751 - compound eye photoreceptor cell differentiation
GO:0005737 - cytoplasm
GO:0007281 - germ cell development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1463049

CSN6
COP9 signalosome complex subunit 6

6

20

Small-scale

0.940

High

1463048

CSN7
COP9 signalosome complex subunit 7

5

19

Small-scale

0.911

High

1463069

CSN5
COP9 signalosome complex subunit 5

2

20

Small-scale

0.759

High

1375262

CSN2
COP9 signalosome complex subunit 2

2

18

High-throughput

0.737

High

1267332

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

18

High-throughput

0.587

High

1269301

CSN8
COP9 signalosome complex subunit 8

1

5

High-throughput

0.575

High

1344397

CSN3
COP9 signalosome complex subunit 3

1

20

High-throughput

0.575

High

1463061

CSN1
COP9 signalosome complex subunit 1b

1

20

High-throughput

0.575

High

652623

BAM
Protein bag of marbles

1

0

Small-scale

0.557

High

1346410

MESD
LDLR chaperone boca

2

0

High-throughput

0.547

High

821874

PSA2
Proteasome subunit alpha type-2

1

20

High-throughput

0.528

High

874993

PRS4
26S proteasome regulatory subunit 4

1

20

High-throughput

0.528

High

1463051

Q9VJJ0
Proteasome subunit beta

1

20

High-throughput

0.528

High

1463068

4EBP
Eukaryotic translation initiation factor 4E-binding protein

1

0

High-throughput

0.513

High

264532

O62602
mitogen-activated protein kinase kinase

1

1

High-throughput

0.508

High

1344952

Q8SZY7
LD06050p

1

1

High-throughput

0.508

High

1378118

Q95TJ6
LP01469p

1

0

High-throughput

0.486

High

1463050

ARP5
Actin-related protein 5

1

0

High-throughput

0.486

High

1463055

TYDP1
Tyrosyl-DNA phosphodiesterase 1

1

0

High-throughput

0.486

High

1463065

RIC8
Chaperone Ric-8

1

0

High-throughput

0.486

High

756483

ECR
Ecdysone receptor

1

7

Small-scale

0.479

High

875250

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.464

High

1267209

Q7KJA9
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.464

High

1463052

VPS54
Vacuolar protein sorting-associated protein 54

1

1

High-throughput

0.464

High

1265530

SEH1
Nucleoporin seh1

1

3

High-throughput

0.445

High

1463059

Q9VSE8
UDP-glucuronic acid decarboxylase 1

1

2

High-throughput

0.445

High

58174

A1ZBG4
Uncharacterized protein, isoform E

1

1

High-throughput

0.439

High

58228

A1ZBG6
Uncharacterized protein, isoform C

1

1

High-throughput

0.417

High

234973

O46085
Peroxisomal targeting signal 1 receptor

1

6

High-throughput

0.417

High

1440768

CARME
Carnosine N-methyltransferase unmet

1

1

High-throughput

0.407

High

1344075

Q8SY07
PRKCA-binding protein

2

0

High-throughput

0.310

High

1196624

Q4V5L1
IP07030p

1

0

High-throughput

0.265

Low

1267473

Q7KM15
Transcription factor BTF3

1

0

High-throughput

0.265

Low

1304174

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.265

Low

1463053

Q9VN78
GEO10179p1

1

0

High-throughput

0.265

Low

1463054

Q9VNS1
UT01871p

1

0

High-throughput

0.265

Low

1463056

Q9VRL0
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.265

Low

1463057

Q9VRN0
Uncharacterized protein

1

0

High-throughput

0.265

Low

1463058

SMSR1
Ceramide phosphoethanolamine synthase

1

0

High-throughput

0.265

Low

1463060

Q9VUL2
GH20023p

1

0

High-throughput

0.265

Low

1463062

Q9VXH7
FI17510p1

1

0

High-throughput

0.265

Low

1463063

Q9VYB1
Kinetochore protein NDC80

1

0

High-throughput

0.265

Low

1463064

CYHR1
Zinc finger TRAF-type-containing protein 1 homolog

1

0

High-throughput

0.265

Low

1463066

USO1
General vesicular transport factor p115

1

0

High-throughput

0.265

Low

1463067

Q9W3S4
LD46272p

1

0

High-throughput

0.265

Low

1269116

Q7KT36
IP19005p

1

0

High-throughput

0.251

Low

55085

A1Z921
Frazzled, isoform B

1

0

Small-scale

0.249

Low

852900

ATTA
Attacin-A

1

0

High-throughput

0.238

Low

1202396

7B2
Neuroendocrine protein 7B2

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025