HitPredict

Interactor 1: RHOD (O00212)
Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1)
Gene: RHOD

Interactor 2: NECT2 (Q92692)
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)
Gene: NECTIN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 210 Hs			1 538
+	Hs
		1269126 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		925492 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		564634 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		545540 RAC2_HUMAN (15-209): 1.06e-73: 222: 45.64		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		892523 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		1335325 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		120659 RHOD_HUMAN (1-210): 1.91e-77: 232: 100.00		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		925647 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		564702 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		892617 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Ce
		136800 RHO1_CAEEL (19-192): 5.35e-89: 261: 54.02		UNC89_CAEEL (251-441): 8.96e-11: 67.1: 12.81
+	Hs
		925776 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		ROBO1_HUMAN (333-538): 1.79e-18: 91.7: 8.92
+	Hs
		1294922 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		120585 RHOD_HUMAN (1-210): 1.91e-77: 232: 100.00		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		564764 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		ROBO1_HUMAN (333-538): 1.79e-18: 91.7: 8.92
+	Hs
		925521 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		564645 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		545561 RAC2_HUMAN (15-209): 1.06e-73: 222: 45.64		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		892541 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Ce
		136793 RAC1_CAEEL (15-203): 3.59e-76: 228: 47.62		UNC89_CAEEL (251-441): 8.96e-11: 67.1: 12.81