Protein: MED31
Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit SOH1) (hSOH1)

Gene: MED31
Organism: Homo sapiens
Interactions: 126
UniProt ID: Q9Y3C7

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

206664

MED7
Mediator of RNA polymerase II transcription subunit 7

6

4

High-throughput

0.955

High

1342962

MED4
Mediator of RNA polymerase II transcription subunit 4

4

1

High-throughput

0.912

High

1346453

MED17
Mediator of RNA polymerase II transcription subunit 17

3

1

High-throughput

0.871

High

225438

MED14
Mediator of RNA polymerase II transcription subunit 14

2

4

High-throughput

0.811

High

625109

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

0

High-throughput

0.770

High

1291856

MED8
Mediator of RNA polymerase II transcription subunit 8

2

0

High-throughput

0.770

High

48755

MED19
Mediator of RNA polymerase II transcription subunit 19

10

1

Small-scale

0.760

High

826381

CDK8
Cyclin-dependent kinase 8

8

4

Small-scale

0.752

High

1314892

CDK19
Cyclin-dependent kinase 19

7

4

High-throughput

0.750

High

1312312

MED10
Mediator of RNA polymerase II transcription subunit 10

6

1

Small-scale

0.738

High

1274370

MED12
Mediator of RNA polymerase II transcription subunit 12

5

2

High-throughput

0.722

High

1312775

MED18
Mediator of RNA polymerase II transcription subunit 18

5

1

High-throughput

0.722

High

624537

CCNC
Cyclin-C

5

1

High-throughput

0.718

High

1356920

MED23
Mediator of RNA polymerase II transcription subunit 23

4

1

High-throughput

0.694

High

1076220

MED1
Mediator of RNA polymerase II transcription subunit 1

5

0

Small-scale

0.691

High

1347861

MED29
Mediator of RNA polymerase II transcription subunit 29

5

0

Small-scale

0.691

High

1328963

MED28
Mediator of RNA polymerase II transcription subunit 28

5

0

High-throughput

0.688

High

1334018

MED20
Mediator of RNA polymerase II transcription subunit 20

3

1

High-throughput

0.675

High

313480

MED26
Mediator of RNA polymerase II transcription subunit 26

4

0

High-throughput

0.674

High

1037117

MED21
Mediator of RNA polymerase II transcription subunit 21

4

0

High-throughput

0.674

High

1355588

MED13
Mediator of RNA polymerase II transcription subunit 13

3

2

High-throughput

0.671

High

1347159

MED9
Mediator of RNA polymerase II transcription subunit 9

4

0

Small-scale

0.667

High

1174791

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

3

2

High-throughput

0.662

High

1074739

MED22
Mediator of RNA polymerase II transcription subunit 22

3

0

High-throughput

0.646

High

265377

MED24
Mediator of RNA polymerase II transcription subunit 24

3

0

High-throughput

0.638

High

270544

MED6
Mediator of RNA polymerase II transcription subunit 6

2

3

High-throughput

0.628

High

1206169

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

2

2

High-throughput

0.628

High

1349552

MED11
Mediator of RNA polymerase II transcription subunit 11

2

1

High-throughput

0.628

High

792116

HD
Huntingtin

2

0

High-throughput

0.604

High

177735

BIRC5
Baculoviral IAP repeat-containing protein 5

2

0

High-throughput

0.602

High

583637

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

High-throughput

0.602

High

583847

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

2

0

High-throughput

0.602

High

677062

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

0

High-throughput

0.602

High

913985

RPB7
DNA-directed RNA polymerase II subunit RPB7

2

0

High-throughput

0.602

High

1158935

MED27
Mediator of RNA polymerase II transcription subunit 27

2

0

High-throughput

0.602

High

1293713

MED30
Mediator of RNA polymerase II transcription subunit 30

2

0

High-throughput

0.602

High

1301103

MED15
Mediator of RNA polymerase II transcription subunit 15

2

0

High-throughput

0.602

High

1377455

MED16
Mediator of RNA polymerase II transcription subunit 16

2

0

High-throughput

0.602

High

1084944

SMN
Survival motor neuron protein

2

0

High-throughput

0.598

High

1293746

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

0

High-throughput

0.580

High

1135251

Q5T911
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.575

High

388817

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.541

High

1022272

HSPB3
Heat shock protein beta-3

1

1

High-throughput

0.541

High

1035299

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

2

High-throughput

0.541

High

1198589

TAD2B
Transcriptional adapter 2-beta

1

3

High-throughput

0.536

High

309889

GA45G
Growth arrest and DNA damage-inducible protein GADD45 gamma

1

0

High-throughput

0.529

High

121879

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

High-throughput

0.518

High

181944

MAFG
Transcription factor MafG

1

0

High-throughput

0.518

High

241918

PQBP1
Polyglutamine-binding protein 1

1

0

High-throughput

0.518

High

312144

LYPA2
Acyl-protein thioesterase 2

1

0

High-throughput

0.518

High

505318

EGR2
E3 SUMO-protein ligase EGR2

1

0

High-throughput

0.518

High

554124

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.518

High

644208

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.518

High

777949

RFC5
Replication factor C subunit 5

1

0

High-throughput

0.518

High

839547

SPB9
Serpin B9

1

0

High-throughput

0.518

High

927789

UBE2B
Ubiquitin-conjugating enzyme E2 B

1

0

High-throughput

0.518

High

950898

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.518

High

993653

TLE5
TLE family member 5

1

0

High-throughput

0.518

High

1075369

TGIF1
Homeobox protein TGIF1

1

0

High-throughput

0.518

High

1158414

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.518

High

1239661

ZSCA1
Zinc finger and SCAN domain-containing protein 1

1

0

High-throughput

0.518

High

1295884

ZBT45
Zinc finger and BTB domain-containing protein 45

1

0

High-throughput

0.518

High

1307070

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.518

High

1312973

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

0

High-throughput

0.518

High

1328744

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.518

High

1377647

EPN1
Epsin-1

1

0

High-throughput

0.518

High

181485

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.513

High

639830

IKBA
NF-kappa-B inhibitor alpha

1

0

High-throughput

0.513

High

738912

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.513

High

854399

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.513

High

865019

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

989418

PRDX1
Peroxiredoxin-1

1

0

High-throughput

0.513

High

1157405

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

High-throughput

0.513

High

1160909

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.513

High

1174980

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.513

High

1221393

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

0

High-throughput

0.513

High

1312048

MTA3
Metastasis-associated protein MTA3

1

0

High-throughput

0.513

High

1377646

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.513

High

378796

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

589258

ANXA7
Annexin A7

1

0

High-throughput

0.486

High

611531

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

0

High-throughput

0.486

High

758370

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.486

High

1065217

DAZP2
DAZ-associated protein 2

1

0

High-throughput

0.486

High

1198933

RBM23
Probable RNA-binding protein 23

1

1

High-throughput

0.481

High

245122

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

266457

TAD2A
Transcriptional adapter 2-alpha

1

3

High-throughput

0.479

High

375136

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

841364

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

1019186

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1078704

SMAD2
Mothers against decapentaplegic homolog 2

1

0

Small-scale

0.458

High

1173792

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.458

High

1281502

FBXW7
F-box/WD repeat-containing protein 7

1

0

Small-scale

0.458

High

1299711

QKI
KH domain-containing RNA-binding protein QKI

1

0

High-throughput

0.458

High

1304840

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

1151906

Q6IA98
RNPC4 protein

1

1

High-throughput

0.457

High

73051

B4DUB1
cDNA FLJ50029, highly similar to Cell division cycle 2-like protein kinase 6

1

4

High-throughput

0.445

High

91320

E5RFK5
Cyclin-C

1

1

High-throughput

0.445

High

1128611

Q5JWT2
Mediator of RNA polymerase II transcription subunit 23

1

1

High-throughput

0.445

High

1312484

HGH1
Protein HGH1 homolog

1

1

High-throughput

0.439

High

124132

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.438

High

1285602

Q96BK8
Protein HGH1 homolog

1

1

High-throughput

0.417

High

1267026

ELMO1
Engulfment and cell motility protein 1

3

0

High-throughput

0.347

High

1028298

SBP1
Methanethiol oxidase

2

0

High-throughput

0.323

High

124985

CACB4
Voltage-dependent L-type calcium channel subunit beta-4

1

0

High-throughput

0.282

High

246065

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.282

High

330031

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.282

High

562499

CBPE
Carboxypeptidase E

1

0

High-throughput

0.282

High

600075

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.282

High

674288

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.282

High

974242

GSTM4
Glutathione S-transferase Mu 4

1

0

High-throughput

0.282

High

983420

DYN1
Dynamin-1

1

0

High-throughput

0.282

High

1067893

PA1B3
Platelet-activating factor acetylhydrolase IB subunit alpha1

1

0

High-throughput

0.282

High

1081787

LAMA4
Laminin subunit alpha-4

1

0

High-throughput

0.282

High

1302312

ORAI2
Protein orai-2

1

0

High-throughput

0.282

High

1306752

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.282

High

1326002

TINAL
Tubulointerstitial nephritis antigen-like

1

0

High-throughput

0.282

High

1332436

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.282

High

1377580

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.282

High

119739

AP4M1
AP-4 complex subunit mu-1

1

0

High-throughput

0.279

Low

1298429

AP4AT
AP-4 complex accessory subunit Tepsin

1

0

High-throughput

0.279

Low

1355607

GPN3
GPN-loop GTPase 3

1

0

High-throughput

0.279

Low

1308678

F118B
Protein FAM118B

1

0

High-throughput

0.265

Low

361625

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.249

Low

199238

LEU1
Leukemia-associated protein 1

1

0

High-throughput

0.238

Low

1348164

NSMA2
Sphingomyelin phosphodiesterase 3

1

0

High-throughput

0.238

Low

1241689

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024