HitPredict

Interactor 1: HIPK1 (Q86Z02)
Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)
Gene: HIPK1

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	28680062
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1210 Hs			1 2442
+	Hs
		1270792 HIPK2_HUMAN (1-1210): 0: 726: 59.04		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		1270794 HIPK3_HUMAN (1-1210): 0: 645: 43.75		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		999086 HIPK2_HUMAN (1-1210): 0: 726: 59.04		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		625532 CDK2_HUMAN (187-524): 3.48e-125: 388: 25.87		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		681959 AKT1_HUMAN (104-507): 3.04e-118: 377: 18.95		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		1044010 DYR1A_HUMAN (188-521): 1.49e-56: 212: 38.42		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		1270845 DYR1B_HUMAN (190-521): 1.98e-57: 212: 37.17		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		625393 CDK2_HUMAN (187-524): 3.48e-125: 388: 25.87		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		566375 KPCA_HUMAN (16-502): 4.25e-117: 380: 15.63		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		681812 AKT1_HUMAN (104-507): 3.04e-118: 377: 18.95		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		998769 MK14_HUMAN (168-558): 4.78e-116: 367: 25.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		414892 CDK1_HUMAN (188-519): 2.21e-110: 349: 23.89		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		998682 DYR1A_HUMAN (188-521): 1.49e-56: 212: 38.42		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		999248 DYR1B_HUMAN (190-521): 1.98e-57: 212: 37.17		EP300_HUMAN (1-2426): 0: 874: 55.06
+	At
		1106545 MPK6_ARATH (150-556): 4.81e-116: 368: 22.03		GTE1_ARATH (1011-1279): 4.44e-42: 162: 19.20
+	Hs
		170273 AKT1_HUMAN (104-507): 3.04e-118: 377: 18.95		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Sc
		562769 FUS3_YEAST (178-550): 5.21e-118: 372: 24.17		BDF2_YEAST (955-1279): 4.05e-26: 118: 14.15
+	Hs
		1082593 MK14_HUMAN (168-558): 4.78e-116: 367: 25.00		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89
+	Hs
		1044321 DYR1A_HUMAN (188-521): 1.49e-56: 212: 38.42		PCLO_HUMAN (1952-2441): 8.89e-13: 76.8: 9.55
+	Ce
		712271 MBK1_CAEEL (196-518): 4.49e-51: 197: 37.27		CBP1_CAEEL (94-860): 3.49e-12: 74.8: 16.69