HitPredict

Interactor 1: MID51 (Q8BGV8)
Mitochondrial dynamics protein MID51 (Mitochondrial dynamics protein of 51 kDa homolog) (Mitochondrial elongation factor 1) (Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like)
Gene: Mief1

Interactor 2: DNM1L (Q8K1M6)
Dynamin-1-like protein (EC 3.6.5.5) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1)
Gene: DNM1L

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.641

Property	Details
Experiments	24508339, 30914652
Identification Methods	anti tag coimmunoprecipitation, transmission electron microscopy, two hybrid, cosedimentation in solution, gtpase assay, cross-linking study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000266 - mitochondrial fission GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0071456 - cellular response to hypoxia GO:0090141 - positive regulation of mitochondrial fission
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 463 Mm			1 736
+	Hs
		128643 MID51_HUMAN (1-463): 0: 781: 97.84		DNM1L_HUMAN (1-736): 0: 919: 98.64
+	Hs
		128613 MID49_HUMAN (1-461): 0: 672: 45.38		DNM1L_HUMAN (1-736): 0: 919: 98.64
+	Mm
		1129456 MID49_MOUSE (1-461): 0: 658: 41.42		DNM1L_MOUSE (1-736): 0: 924: 100.00