Protein: SPB7
Serpin B7 (Megsin) (TP55)

Gene: SPB7, SERPINB7
Organism: Homo sapiens
Interactions: 65
UniProt ID: O75635

Gene Ontology (top 5):
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0032914 - positive regulation of transforming growth factor beta1 production
GO:0032967 - positive regulation of collagen biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

271897

PLK2
Serine/threonine-protein kinase PLK2

3

3

High-throughput

0.667

High

271848

FRIH
Ferritin heavy chain

2

5

High-throughput

0.628

High

271855

GDF5
Growth/differentiation factor 5

2

4

High-throughput

0.628

High

271886

CDK15
Cyclin-dependent kinase 15

2

7

High-throughput

0.628

High

271865

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

2

2

High-throughput

0.611

High

271900

DD19B
ATP-dependent RNA helicase DDX19B

2

9

High-throughput

0.611

High

271866

KI3S1
Killer cell immunoglobulin-like receptor 3DS1

3

7

High-throughput

0.609

High

271867

NONO
Non-POU domain-containing octamer-binding protein

2

3

High-throughput

0.574

High

271895

TB22B
TBC1 domain family member 22B

2

7

High-throughput

0.574

High

271860

CF298
Cilia- and flagella-associated protein 298

2

4

High-throughput

0.558

High

271844

RENR
Renin receptor

1

6

High-throughput

0.536

High

271846

SG1D1
Secretoglobin family 1D member 1

1

4

High-throughput

0.536

High

271847

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

4

High-throughput

0.536

High

271849

IFNA4
Interferon alpha-4

1

2

High-throughput

0.536

High

271850

AATC
Aspartate aminotransferase, cytoplasmic

1

8

High-throughput

0.536

High

271853

CCR1
C-C chemokine receptor type 1

1

7

High-throughput

0.536

High

271862

SSBP2
Single-stranded DNA-binding protein 2

1

5

High-throughput

0.536

High

271891

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

7

High-throughput

0.536

High

271894

MBNL1
Muscleblind-like protein 1

1

5

High-throughput

0.536

High

271898

HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2

1

4

High-throughput

0.536

High

271903

SSUH2
Protein SSUH2 homolog

1

8

High-throughput

0.536

High

271904

RN115
E3 ubiquitin-protein ligase RNF115

1

7

High-throughput

0.536

High

271852

PURA2
Adenylosuccinate synthetase isozyme 2

1

0

High-throughput

0.513

High

271879

D106A
Beta-defensin 106

1

0

High-throughput

0.513

High

174333

FANCG
Fanconi anemia group G protein

1

2

High-throughput

0.489

High

206883

CHSTA
Carbohydrate sulfotransferase 10

1

4

High-throughput

0.489

High

215790

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

4

High-throughput

0.489

High

237635

SEP15
Selenoprotein F

1

4

High-throughput

0.489

High

271845

OR2A4
Olfactory receptor 2A4

1

13

High-throughput

0.489

High

271851

CCNC
Cyclin-C

1

6

High-throughput

0.489

High

271856

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.489

High

271858

STX17
Syntaxin-17

1

10

High-throughput

0.489

High

271859

DSCR6
Protein ripply3

1

7

High-throughput

0.489

High

271861

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

5

High-throughput

0.489

High

271863

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

3

High-throughput

0.489

High

271864

GABPA
GA-binding protein alpha chain

1

6

High-throughput

0.489

High

271868

CR021
UPF0711 protein C18orf21

1

6

High-throughput

0.489

High

271870

VWA3B
von Willebrand factor A domain-containing protein 3B

1

1

High-throughput

0.489

High

271871

LRC10
Leucine-rich repeat-containing protein 10

1

4

High-throughput

0.489

High

271872

AMTN
Amelotin

1

1

High-throughput

0.489

High

271874

MOGT3
2-acylglycerol O-acyltransferase 3

1

7

High-throughput

0.489

High

271875

ZC3C1
Zinc finger C3HC-type protein 1

1

5

High-throughput

0.489

High

271876

AROS
Active regulator of SIRT1

1

2

High-throughput

0.489

High

271877

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

2

High-throughput

0.489

High

271878

EPHX4
Epoxide hydrolase 4

1

3

High-throughput

0.489

High

271881

RHBL4
Rhomboid-related protein 4

1

4

High-throughput

0.489

High

271882

ZDH19
Palmitoyltransferase ZDHHC19

1

3

High-throughput

0.489

High

271883

THAP4
Peroxynitrite isomerase THAP4

1

3

High-throughput

0.489

High

271884

PIGT
GPI transamidase component PIG-T

1

4

High-throughput

0.489

High

271885

SARAF
Store-operated calcium entry-associated regulatory factor

1

9

High-throughput

0.489

High

271887

TEFM
Transcription elongation factor, mitochondrial

1

4

High-throughput

0.489

High

271889

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

7

High-throughput

0.489

High

271890

MMTA2
Multiple myeloma tumor-associated protein 2

1

5

High-throughput

0.489

High

271892

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

1

High-throughput

0.489

High

271893

TSSP
Thymus-specific serine protease

1

5

High-throughput

0.489

High

271896

KLH11
Kelch-like protein 11

1

6

High-throughput

0.489

High

271899

PHF11
PHD finger protein 11

1

8

High-throughput

0.489

High

271901

PHF8
Histone lysine demethylase PHF8

1

3

High-throughput

0.489

High

271902

FOXJ3
Forkhead box protein J3

1

4

High-throughput

0.489

High

271857

SOX2
Transcription factor SOX-2

1

13

High-throughput

0.479

High

271869

Q4LE69
1-phosphatidylinositol 4-kinase

1

11

High-throughput

0.479

High

271873

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

271888

RANB9
Ran-binding protein 9

1

5

Small-scale

0.479

High

271854

PI4KA
Phosphatidylinositol 4-kinase alpha

1

11

High-throughput

0.445

High

271880

PI4P1
Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

1

11

High-throughput

0.407

High


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Last updated: 15 Jul 2024