Protein: DGCR6
Protein DGCR6 (DiGeorge syndrome critical region 6)

Gene: DGCR6
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q14129

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0007155 - cell adhesion
GO:0009887 - animal organ morphogenesis
GO:0031012 - extracellular matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1120880

SOSSC
SOSS complex subunit C

2

1

High-throughput

0.606

High

464260

FUMH
Fumarate hydratase, mitochondrial

2

0

High-throughput

0.580

High

1120872

ESS2
Splicing factor ESS-2 homolog

2

0

High-throughput

0.580

High

1120894

AKP8L
A-kinase anchor protein 8-like

2

0

High-throughput

0.580

High

1060014

DLX2
Homeobox protein DLX-2

1

1

High-throughput

0.541

High

1103160

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.541

High

1120877

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

1

1

High-throughput

0.541

High

351535

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

0

High-throughput

0.518

High

1120875

PRD14
PR domain zinc finger protein 14

1

0

High-throughput

0.518

High

1120885

DLGP2
Disks large-associated protein 2

1

1

High-throughput

0.494

High

1120865

REXO1
RNA exonuclease 1 homolog

1

0

High-throughput

0.493

High

163433

MEIS2
Homeobox protein Meis2

1

1

High-throughput

0.481

High

221125

SPY2
Protein sprouty homolog 2

1

1

High-throughput

0.481

High

274000

CREST
Calcium-responsive transactivator

1

1

High-throughput

0.481

High

354224

ZBED1
E3 SUMO-protein ligase ZBED1

1

1

High-throughput

0.481

High

571969

TRI27
Zinc finger protein RFP

1

1

High-throughput

0.481

High

587079

ITF2
Transcription factor 4

1

3

High-throughput

0.481

High

893860

MEOX2
Homeobox protein MOX-2

1

2

High-throughput

0.481

High

934591

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.481

High

1048849

REL
Proto-oncogene c-Rel

1

2

High-throughput

0.481

High

1061694

TLE5
TLE family member 5

1

1

High-throughput

0.481

High

1120850

NAB2
NGFI-A-binding protein 2

1

2

High-throughput

0.481

High

1120858

HAKAI
E3 ubiquitin-protein ligase Hakai

1

1

High-throughput

0.481

High

1120862

RFX6
DNA-binding protein RFX6

1

1

High-throughput

0.481

High

1120869

MIPO1
Mirror-image polydactyly gene 1 protein

1

1

High-throughput

0.481

High

1120870

ZN398
Zinc finger protein 398

1

1

High-throughput

0.481

High

1120873

HTF4
Transcription factor 12

1

3

High-throughput

0.481

High

1120878

ZC4H2
Zinc finger C4H2 domain-containing protein

1

1

High-throughput

0.481

High

1120883

ZN446
Zinc finger protein 446

1

2

High-throughput

0.481

High

1120887

TFP11
Tuftelin-interacting protein 11

1

1

High-throughput

0.481

High

1120888

RIM3A
RIMS-binding protein 3A

1

2

High-throughput

0.481

High

1120892

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.481

High

1120893

DNPEP
Aspartyl aminopeptidase

1

1

High-throughput

0.481

High

422093

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1045272

TF65
Transcription factor p65

1

2

Small-scale

0.479

High

1120882

BMP2K
BMP-2-inducible protein kinase

1

0

Small-scale

0.473

High

1120863

HOMEZ
Homeobox and leucine zipper protein Homez

1

0

High-throughput

0.460

High

830713

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

169550

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.439

High

1053399

DEUP1
Deuterosome assembly protein 1

1

2

High-throughput

0.439

High

1063240

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.439

High

1090636

TRAF2
TNF receptor-associated factor 2

1

6

High-throughput

0.439

High

1093813

TRAF1
TNF receptor-associated factor 1

1

3

High-throughput

0.439

High

1120849

GSE1
Genetic suppressor element 1

1

1

High-throughput

0.439

High

1120853

EFHC2
EF-hand domain-containing family member C2

1

1

High-throughput

0.439

High

1120854

CA094
Uncharacterized protein C1orf94

1

1

High-throughput

0.439

High

1120855

ATRAP
Type-1 angiotensin II receptor-associated protein

1

1

High-throughput

0.439

High

1120856

ATL4
ADAMTS-like protein 4

1

2

High-throughput

0.439

High

1120860

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.439

High

1120861

NECA2
N-terminal EF-hand calcium-binding protein 2

1

2

High-throughput

0.439

High

1120864

IHO1
Interactor of HORMAD1 protein 1

1

1

High-throughput

0.439

High

1120866

CCD33
Coiled-coil domain-containing protein 33

1

1

High-throughput

0.439

High

1120867

CBY2
Protein chibby homolog 2

1

1

High-throughput

0.439

High

1120868

DOCK8
Dedicator of cytokinesis protein 8

1

1

High-throughput

0.439

High

1120871

FBF1
Fas-binding factor 1

1

1

High-throughput

0.439

High

1120874

LZTS2
Leucine zipper putative tumor suppressor 2

1

2

High-throughput

0.439

High

1120876

ENKD1
Enkurin domain-containing protein 1

1

1

High-throughput

0.439

High

1120879

PDLI7
PDZ and LIM domain protein 7

1

1

High-throughput

0.439

High

1120881

MBIP1
MAP3K12-binding inhibitory protein 1

1

2

High-throughput

0.439

High

1120886

CE126
Centrosomal protein of 126 kDa

1

1

High-throughput

0.439

High

1120889

GCP4
Gamma-tubulin complex component 4

1

1

High-throughput

0.439

High

1120890

RABX5
Rab5 GDP/GTP exchange factor

1

1

High-throughput

0.439

High

1120891

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

4

High-throughput

0.439

High

948316

KR122
Keratin-associated protein 12-2

2

0

High-throughput

0.316

High

351484

FTCD
Formimidoyltransferase-cyclodeaminase

1

0

High-throughput

0.282

High

591421

NQO2
Ribosyldihydronicotinamide dehydrogenase [quinone]

1

0

High-throughput

0.282

High

789111

NUP62
Nuclear pore glycoprotein p62

1

0

High-throughput

0.282

High

1120851

KLH12
Kelch-like protein 12

1

0

High-throughput

0.282

High

1120857

CC062
Uncharacterized protein C3orf62

1

0

High-throughput

0.282

High

1120859

NUP54
Nucleoporin p54

1

0

High-throughput

0.282

High

247115

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.279

Low

1120852

XKR4
XK-related protein 4

1

0

High-throughput

0.279

Low

1120884

NPAP1
Nuclear pore-associated protein 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025