HitPredict

Interactor 1: WBP1L (Q8BGW2)
WW domain binding protein 1-like (Outcome predictor in acute leukemia 1 homolog)
Gene: WBP1L

Interactor 2: ITCH (Q8C863)
E3 ubiquitin-protein ligase Itchy (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase Itchy homolog)
Gene: ITCH

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31845480
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 348 Mm			1 864
+	Mm
		1206454 WBP1L_MOUSE (1-348): 0: 592: 100.00		WWP1_MOUSE (1-864): 0: 845: 57.68
+	Mm
		1206456 WBP1L_MOUSE (1-348): 0: 592: 100.00		WWP2_MOUSE (1-864): 0: 827: 55.90
+	Mm
		93278 WBP1L_MOUSE (1-348): 0: 592: 100.00		E9PXB7_MOUSE (111-861): 0: 689: 34.77
+	Hs
		1291858 WBP1_HUMAN (8-274): 3.02e-85: 260: 37.87		ITCH_HUMAN (1-864): 0: 899: 91.27
+	Hs
		125643 WBP1_HUMAN (8-274): 3.02e-85: 260: 37.87		WWP2_HUMAN (1-864): 0: 829: 56.01
+	Hs
		1291863 WBP1_HUMAN (8-274): 3.02e-85: 260: 37.87		WWP1_HUMAN (1-864): 0: 828: 57.33
+	Hs
		1291859 WBP1_HUMAN (8-274): 3.02e-85: 260: 37.87		NED4L_HUMAN (1-861): 0: 795: 32.68
+	Mm
		808346 WBP1_MOUSE (10-274): 9.44e-79: 245: 35.56		NEDD4_MOUSE (3-861): 0: 744: 32.18
+	Hs
		808224 WBP1_HUMAN (8-274): 3.02e-85: 260: 37.87		NEDD4_HUMAN (90-861): 0: 728: 35.88
+	Hs
		1291869 WBP1_HUMAN (8-274): 3.02e-85: 260: 37.87		HECW2_HUMAN (1-376): 7.48e-14: 78: 10.86