Protein: FBXW8
F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8) (F-box only protein 29)

Gene: FBXW8
Organism: Homo sapiens
Interactions: 151
UniProt ID: Q8N3Y1

Gene Ontology (top 5):
GO:0005794 - Golgi apparatus
GO:0005814 - centriole
GO:0005829 - cytosol
GO:0007030 - Golgi organization
GO:0008283 - cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

928984

SKP1
S-phase kinase-associated protein 1

13

20

Small-scale

0.980

High

1061494

CUL7
Cullin-7

13

5

Small-scale

0.979

High

1041090

CUL1
Cullin-1

9

20

Small-scale

0.973

High

1043100

CUL4A
Cullin-4A

2

20

Small-scale

0.754

High

1232710

FBW1A
F-box/WD repeat-containing protein 1A

2

19

Small-scale

0.754

High

921340

RBX1
E3 ubiquitin-protein ligase RBX1

6

15

Small-scale

0.726

High

387091

P53
Cellular tumor antigen p53

5

8

Small-scale

0.709

High

1041396

CUL2
Cullin-2

1

20

Small-scale

0.691

High

826762

TCPG
T-complex protein 1 subunit gamma

3

20

Small-scale

0.675

High

1232692

TCPH
T-complex protein 1 subunit eta

3

20

Small-scale

0.675

High

724552

IRS1
Insulin receptor substrate 1

3

10

Small-scale

0.674

High

943347

TCPB
T-complex protein 1 subunit beta

3

20

Small-scale

0.667

High

1082591

MK14
Mitogen-activated protein kinase 14

3

9

High-throughput

0.667

High

1232697

CCDC8
Coiled-coil domain-containing protein 8

3

1

Small-scale

0.656

High

622494

CCND1
G1/S-specific cyclin-D1

2

11

Small-scale

0.624

High

1031230

SKP2
S-phase kinase-associated protein 2

1

4

Small-scale

0.618

High

1232669

FBXW8
F-box/WD repeat-containing protein 8

1

19

High-throughput

0.618

High

1232707

FBXW2
F-box/WD repeat-containing protein 2

1

19

Small-scale

0.618

High

255924

OBSL1
Obscurin-like protein 1

2

6

Small-scale

0.611

High

307195

KLHL2
Kelch-like protein 2

2

4

High-throughput

0.611

High

821310

TCPE
T-complex protein 1 subunit epsilon

2

20

High-throughput

0.611

High

159722

CASQ2
Calsequestrin-2

3

9

High-throughput

0.609

High

1232672

TTC29
Tetratricopeptide repeat protein 29

3

1

High-throughput

0.609

High

1232706

FBX4
F-box only protein 4

1

0

Small-scale

0.586

High

1043454

CUL4B
Cullin-4B

1

20

High-throughput

0.575

High

161849

ZN263
Zinc finger protein 263

2

5

High-throughput

0.574

High

1232682

ZN669
Zinc finger protein 669

2

1

High-throughput

0.574

High

347316

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.542

High

770926

TCPZ
T-complex protein 1 subunit zeta

1

20

Small-scale

0.536

High

829618

DGKG
Diacylglycerol kinase gamma

1

3

High-throughput

0.536

High

901699

PFD3
Prefoldin subunit 3

1

4

Small-scale

0.536

High

997809

RBBP4
Histone-binding protein RBBP4

1

17

High-throughput

0.536

High

1079103

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.536

High

1232674

SNX33
Sorting nexin-33

1

2

High-throughput

0.536

High

1232677

TCPW
T-complex protein 1 subunit zeta-2

1

20

Small-scale

0.536

High

1232690

PFD5
Prefoldin subunit 5

1

5

Small-scale

0.536

High

1232698

PDCL3
Phosducin-like protein 3

1

7

High-throughput

0.536

High

153466

PDCD5
Programmed cell death protein 5

1

0

Small-scale

0.513

High

1016732

CETN1
Centrin-1

1

0

High-throughput

0.513

High

895844

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

13

Small-scale

0.501

High

1232689

TRIB1
Tribbles homolog 1

1

10

Small-scale

0.501

High

950521

ARF1
ADP-ribosylation factor 1

1

3

Small-scale

0.500

High

1075931

PCH2
Pachytene checkpoint protein 2 homolog

1

17

Small-scale

0.489

High

1078401

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

5

High-throughput

0.489

High

1232671

TTC9C
Tetratricopeptide repeat protein 9C

1

9

High-throughput

0.489

High

1232705

FBLN5
Fibulin-5

1

6

High-throughput

0.489

High

49640

RHG10
Rho GTPase-activating protein 10

1

6

High-throughput

0.479

High

162987

XPO1
Exportin-1

1

10

High-throughput

0.479

High

198667

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

1

High-throughput

0.479

High

201367

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

4

Small-scale

0.479

High

237610

DIAP1
Protein diaphanous homolog 1

1

4

High-throughput

0.479

High

302184

AP2A2
AP-2 complex subunit alpha-2

1

5

High-throughput

0.479

High

432053

HS90A
Heat shock protein HSP 90-alpha

1

15

Small-scale

0.479

High

451930

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

2

High-throughput

0.479

High

498311

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

2

High-throughput

0.479

High

503295

MTAP2
Microtubule-associated protein 2

1

11

High-throughput

0.479

High

573363

TCPA
T-complex protein 1 subunit alpha

1

20

Small-scale

0.479

High

595678

BCL3
B-cell lymphoma 3 protein

1

20

Small-scale

0.479

High

598224

FLNA
Filamin-A

1

12

High-throughput

0.479

High

637483

PSA1
Proteasome subunit alpha type-1

1

4

High-throughput

0.479

High

639774

IKBA
NF-kappa-B inhibitor alpha

1

20

Small-scale

0.479

High

647103

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

653315

PYR1
Multifunctional protein CAD

1

7

High-throughput

0.479

High

656624

PSB6
Proteasome subunit beta type-6

1

2

High-throughput

0.479

High

714303

HSP74
Heat shock 70 kDa protein 4

1

11

Small-scale

0.479

High

796235

MAGAA
Melanoma-associated antigen 10

1

8

High-throughput

0.479

High

826004

FAS
Fatty acid synthase

1

2

High-throughput

0.479

High

853368

IMA1
Importin subunit alpha-1

1

4

High-throughput

0.479

High

853945

NCBP2
Nuclear cap-binding protein subunit 2

1

15

High-throughput

0.479

High

891560

MYL6
Myosin light polypeptide 6

1

3

High-throughput

0.479

High

927845

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

2

High-throughput

0.479

High

932258

ACTC
Actin, alpha cardiac muscle 1

1

6

High-throughput

0.479

High

985720

DEUP1
Deuterosome assembly protein 1

1

19

High-throughput

0.479

High

986699

EXOS9
Exosome complex component RRP45

1

2

High-throughput

0.479

High

994768

GOGA3
Golgin subfamily A member 3

1

9

High-throughput

0.479

High

998883

EP300
Histone acetyltransferase p300

1

12

Small-scale

0.479

High

1016496

TWF1
Twinfilin-1

1

3

High-throughput

0.479

High

1025042

REST
RE1-silencing transcription factor

1

4

Small-scale

0.479

High

1030356

G3BP1
Ras GTPase-activating protein-binding protein 1

1

8

High-throughput

0.479

High

1049264

KEAP1
Kelch-like ECH-associated protein 1

1

4

High-throughput

0.479

High

1066392

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

1082278

DDB1
DNA damage-binding protein 1

1

11

Small-scale

0.479

High

1115544

GLYR1
Cytokine-like nuclear factor N-PAC

1

7

High-throughput

0.479

High

1136501

TTBK1
Tau-tubulin kinase 1

1

19

High-throughput

0.479

High

1174817

LARP4
La-related protein 4

1

6

High-throughput

0.479

High

1191397

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

1

1

High-throughput

0.479

High

1191690

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

10

High-throughput

0.479

High

1197811

PHLB2
Pleckstrin homology-like domain family B member 2

1

18

High-throughput

0.479

High

1218745

GCC2
GRIP and coiled-coil domain-containing protein 2

1

8

High-throughput

0.479

High

1232676

DNJC9
DnaJ homolog subfamily C member 9

1

17

High-throughput

0.479

High

1232678

LPIN2
Phosphatidate phosphatase LPIN2

1

6

High-throughput

0.479

High

1232680

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

16

Small-scale

0.479

High

1232684

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

18

High-throughput

0.479

High

1232686

LRCH3
DISP complex protein LRCH3

1

9

High-throughput

0.479

High

1232688

ZDH15
Palmitoyltransferase ZDHHC15

1

2

High-throughput

0.479

High

1232691

ATX2
Ataxin-2

1

11

Small-scale

0.479

High

1232693

GORS1
Golgi reassembly-stacking protein 1

1

1

Small-scale

0.479

High

1232696

IF5A2
Eukaryotic translation initiation factor 5A-2

1

3

High-throughput

0.479

High

1232699

DOCK5
Dedicator of cytokinesis protein 5

1

5

High-throughput

0.479

High

1232708

G3BP2
Ras GTPase-activating protein-binding protein 2

1

9

High-throughput

0.479

High

1232675

PCNP
PEST proteolytic signal-containing nuclear protein

1

0

High-throughput

0.458

High

1232712

RT16
Small ribosomal subunit protein bS16m

1

0

High-throughput

0.458

High

1232713

MOFA1
MORF4 family-associated protein 1

1

0

Small-scale

0.458

High

130331

NR5A2
Nuclear receptor subfamily 5 group A member 2

1

14

High-throughput

0.437

High

171648

PFD6
Prefoldin subunit 6

1

4

High-throughput

0.437

High

241040

RT14
Small ribosomal subunit protein uS14m

1

1

High-throughput

0.437

High

275334

UDB17
UDP-glucuronosyltransferase 2B17

1

1

High-throughput

0.437

High

398195

PERM
Myeloperoxidase

1

1

High-throughput

0.437

High

415408

ATPB
ATP synthase subunit beta, mitochondrial

1

9

High-throughput

0.437

High

489777

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.437

High

540436

MMP9
Matrix metalloproteinase-9

1

3

High-throughput

0.437

High

551775

DESP
Desmoplakin

1

16

High-throughput

0.437

High

771510

CTRL
Chymotrypsin-like protease CTRL-1

1

1

High-throughput

0.437

High

786010

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

3

High-throughput

0.437

High

877427

LAMB2
Laminin subunit beta-2

1

4

High-throughput

0.437

High

1060140

ARI5B
AT-rich interactive domain-containing protein 5B

1

6

High-throughput

0.437

High

1103303

FHOD3
FH1/FH2 domain-containing protein 3

1

3

High-throughput

0.437

High

1123380

BRDT
Bromodomain testis-specific protein

1

20

High-throughput

0.437

High

1134366

KPRP
Keratinocyte proline-rich protein

1

2

High-throughput

0.437

High

1137442

F222A
Protein FAM222A

1

2

High-throughput

0.437

High

1157208

H3C
Histone H3.3C

1

10

High-throughput

0.437

High

1157943

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

2

High-throughput

0.437

High

1200975

LUZP1
Leucine zipper protein 1

1

19

High-throughput

0.437

High

1223896

GP135
G-protein coupled receptor 135

1

1

High-throughput

0.437

High

1232670

CBR4
3-oxoacyl-[acyl-carrier-protein] reductase

1

1

High-throughput

0.437

High

1232673

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

5

High-throughput

0.437

High

1232679

SEM4D
Semaphorin-4D

1

2

High-throughput

0.437

High

1232681

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

2

High-throughput

0.437

High

1232683

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

2

High-throughput

0.437

High

1232685

DISP1
Protein dispatched homolog 1

1

1

High-throughput

0.437

High

1232687

YTDC1
YTH domain-containing protein 1

1

8

High-throughput

0.437

High

1232701

NANOG
Homeobox protein NANOG

1

15

Small-scale

0.437

High

1232702

ATD3A
ATPase family AAA domain-containing protein 3A

1

13

High-throughput

0.437

High

1232703

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

1

High-throughput

0.437

High

1232704

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

8

High-throughput

0.437

High

1232709

RL26L
Ribosomal protein uL24-like

1

4

High-throughput

0.437

High

1232715

PCLO
Protein piccolo

1

5

High-throughput

0.437

High

89974

D6R9G5
Kelch like family member 2

1

5

High-throughput

0.407

High

230397

ZC3H1
Zinc finger C3H1 domain-containing protein

2

0

High-throughput

0.328

High

1232700

ZN408
Zinc finger protein 408

2

0

High-throughput

0.328

High

1120612

ZC21C
Zinc finger C2HC domain-containing protein 1C

1

0

High-throughput

0.279

Low

1232694

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.279

Low

67941

SPMA1
Sperm microtubule associated protein 1

1

0

High-throughput

0.249

Low

266196

ERLN1
Erlin-1

1

0

High-throughput

0.249

Low

964890

DIAC
Di-N-acetylchitobiase

1

0

High-throughput

0.249

Low

1169308

ACP7
Acid phosphatase type 7

1

0

High-throughput

0.249

Low

1198747

RM52
Large ribosomal subunit protein mL52

1

0

High-throughput

0.249

Low

1232695

SMAKA
Small membrane A-kinase anchor protein

1

0

High-throughput

0.249

Low

1232711

VWA7
von Willebrand factor A domain-containing protein 7

1

0

High-throughput

0.249

Low

1232714

COX11
Cytochrome c oxidase assembly protein COX11, mitochondrial

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024