HitPredict

Interactor 1: DOCK1 (Q8BUR4)
Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)
Gene: DOCK1

Interactor 2: ELMO3 (Q8BYZ7)
Engulfment and cell motility protein 3
Gene: ELMO3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DOCK_N~PH_12
Common GO terms	GO:0005737 - cytoplasm GO:0006909 - phagocytosis GO:0006915 - apoptotic process GO:0017124 - SH3 domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1865 Mm			1 720
+	Mm
		1207128 DOCK1_MOUSE (1-1819): 0: 2266: 100.00		ELMO1_MOUSE (1-716): 0: 951: 52.33
+	Hs
		1050487 DOCK1_HUMAN (1-1823): 0: 2255: 96.65		ELMO3_HUMAN (1-720): 0: 960: 90.83
+	Hs
		1050484 DOCK1_HUMAN (1-1823): 0: 2255: 96.65		ELMO1_HUMAN (1-716): 0: 949: 52.33
+	Mm
		1206593 DOCK1_MOUSE (1-1819): 0: 2266: 100.00		ELMO2_MOUSE (1-715): 0: 916: 50.14
+	Hs
		1050489 DOCK1_HUMAN (1-1823): 0: 2255: 96.65		ELMO2_HUMAN (1-715): 0: 926: 50.97
+	Hs
		1267020 DOCK2_HUMAN (1-1804): 0: 2037: 59.45		ELMO1_HUMAN (1-716): 0: 949: 52.33
+	Hs
		1267934 DOCK2_HUMAN (1-1804): 0: 2037: 59.45		ELMO2_HUMAN (1-715): 0: 926: 50.97
+	Hs
		1285559 DOCK5_HUMAN (1-1830): 0: 1993: 63.02		ELMO3_HUMAN (1-720): 0: 960: 90.83
+	Mm
		1207130 DOCK2_MOUSE (1-1804): 0: 1994: 59.10		ELMO1_MOUSE (1-716): 0: 951: 52.33
+	Hs
		1267024 DOCK5_HUMAN (1-1830): 0: 1993: 63.02		ELMO1_HUMAN (1-716): 0: 949: 52.33
+	Hs
		1295265 DOCK5_HUMAN (1-1830): 0: 1993: 63.02		ELMO2_HUMAN (1-715): 0: 926: 50.97
+	Hs
		1224225 DOCK3_HUMAN (4-1860): 0: 1839: 36.47		ELMO3_HUMAN (1-720): 0: 960: 90.83
+	Hs
		1224220 DOCK3_HUMAN (4-1860): 0: 1839: 36.47		ELMO1_HUMAN (1-716): 0: 949: 52.33
+	Hs
		1230990 DOCK4_HUMAN (4-1862): 0: 1825: 36.34		ELMO3_HUMAN (1-720): 0: 960: 90.83
+	Hs
		1230987 DOCK4_HUMAN (4-1862): 0: 1825: 36.34		ELMO1_HUMAN (1-716): 0: 949: 52.33
+	Hs
		1224227 DOCK3_HUMAN (4-1860): 0: 1839: 36.47		ELMO2_HUMAN (1-715): 0: 926: 50.97
+	Hs
		1230992 DOCK4_HUMAN (4-1862): 0: 1825: 36.34		ELMO2_HUMAN (1-715): 0: 926: 50.97
+	Hs
		1061751 Q149N5_HUMAN (4-1862): 0: 1795: 35.41		ELMO2_HUMAN (1-715): 0: 926: 50.97
+	Dm
		1362934 Q9VCH4_DROME (1-1822): 0: 1842: 38.72		Q9VKB2_DROME (5-714): 0: 816: 42.76
+	Dm
		81396 B7Z0R2_DROME (4-1764): 0: 1684: 36.01		Q9VKB2_DROME (5-714): 0: 816: 42.76