Protein: SPNDC
Spindlin interactor and repressor of chromatin-binding protein (SPIN1-docking protein) (SPIN-DOC)

Gene: SPNDC, SPINDOC
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q9BUA3

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006974 - DNA damage response
GO:0010835 - regulation of protein ADP-ribosylation
GO:0045892 - negative regulation of DNA-templated transcription
GO:0090734 - site of DNA damage

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1414060

SPIN1
Spindlin-1

4

2

High-throughput

0.691

High

1409749

SPI2B
Spindlin-2B

3

2

High-throughput

0.609

High

1207312

SPIN3
Spindlin-3

3

2

High-throughput

0.604

High

297861

PIAS2
E3 SUMO-protein ligase PIAS2

2

0

High-throughput

0.580

High

1392876

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1097161

MK07
Mitogen-activated protein kinase 7

2

0

High-throughput

0.547

High

1215800

RC3H1
Roquin-1

2

1

High-throughput

0.533

High

1408409

SH3G3
Endophilin-A3

2

1

High-throughput

0.521

High

212858

ZBT43
Zinc finger and BTB domain-containing protein 43

1

0

High-throughput

0.513

High

225431

CIKS
E3 ubiquitin ligase TRAF3IP2

1

0

High-throughput

0.513

High

348887

CLIC3
Chloride intracellular channel protein 3

1

0

High-throughput

0.513

High

621952

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

1207011

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

0

High-throughput

0.513

High

1404887

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.513

High

971943

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.493

High

1414054

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

1

High-throughput

0.479

High

138294

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

257497

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

320024

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

349225

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.458

High

350130

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

363799

EGFR
Epidermal growth factor receptor

1

0

Small-scale

0.458

High

446029

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

543278

UBL4A
Ubiquitin-like protein 4A

1

0

High-throughput

0.458

High

862418

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

897382

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

957499

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

971007

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

998756

H31
Histone H3.1

1

0

High-throughput

0.458

High

1045714

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1235674

NIPBL
Nipped-B-like protein

1

0

High-throughput

0.458

High

1308480

VRK3
Serine/threonine-protein kinase VRK3

1

0

High-throughput

0.458

High

1390526

CDCA5
Sororin

1

0

High-throughput

0.458

High

1400503

ASB2
Ankyrin repeat and SOCS box protein 2

1

0

High-throughput

0.458

High

1403127

CRBN
Protein cereblon

1

0

Small-scale

0.458

High

1407840

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1414048

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1414056

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1414057

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.458

High

1414051

RC3H2
Roquin-2

1

2

High-throughput

0.437

High

530310

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

732691

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.426

High

987910

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.426

High

1103354

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.426

High

1414059

LOXL2
Lysyl oxidase homolog 2

1

0

Small-scale

0.426

High

249780

DOK2
Docking protein 2

2

0

High-throughput

0.298

High

1116693

RIN1
Ras and Rab interactor 1

2

0

High-throughput

0.298

High

347293

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

1280181

RABEK
Rab9 effector protein with kelch motifs

1

0

High-throughput

0.279

Low

1414052

IL26
Interleukin-26

1

0

High-throughput

0.279

Low

1414058

AR2BP
ADP-ribosylation factor-like protein 2-binding protein

1

0

High-throughput

0.279

Low

1414061

CFA20
Cilia- and flagella-associated protein 20

1

0

High-throughput

0.279

Low

728818

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

High-throughput

0.268

Low

50871

NDUF8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8

1

0

Small-scale

0.249

Low

294269

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1396792

SNX27
Sorting nexin-27

1

0

High-throughput

0.249

Low

1414049

GAN
Gigaxonin

1

0

High-throughput

0.249

Low

1414050

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1414053

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.249

Low

1414055

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low

87533

OSCRI
SCRIB overlapping open reading frame protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025