HitPredict

Interactor 1: APBB1 (O00213)
Amyloid beta precursor protein binding family B member 1 (Amyloid-beta A4 precursor protein-binding family B member 1) (Protein Fe65)
Gene: APBB1

Interactor 2: APBB1 (O00213)
Amyloid beta precursor protein binding family B member 1 (Amyloid-beta A4 precursor protein-binding family B member 1) (Protein Fe65)
Gene: APBB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 15044485, 24284412
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PID~PID, WW~WW
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001540 - amyloid-beta binding
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
and 26 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 710
Hs

1 710
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024