Interactor 1: MP2K7 (Q8CE90)
Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2)
Gene: Map2k7

Interactor 2: JIP3 (Q9ESN9)
C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Mitogen-activated protein kinase 8-interacting protein 3) (Sunday driver 2)
Gene: Mapk8ip3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 10629060, 15767678
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0007254 - JNK cascade
GO:0031435 - mitogen-activated protein kinase kinase kinase binding
GO:0043507 - positive regulation of JUN kinase activity
GO:0046330 - positive regulation of JNK cascade
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 535
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Last updated: 15 Jul 2024