Protein: SPXN2
Sperm protein associated with the nucleus on the X chromosome N2 (Nuclear-associated protein SPAN-Xn2) (SPANX-N2) (SPANX family member N2)

Gene: SPXN2, SPANXN2
Organism: Homo sapiens
Interactions: 96
UniProt ID: Q5MJ10

Gene Ontology (top 5):

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1208294

CAVN1
Caveolae-associated protein 1

3

1

High-throughput

0.607

High

517663

ZBT48
Zinc finger and BTB domain-containing protein 48

2

2

High-throughput

0.553

High

600059

ZNF19
Zinc finger protein 19

2

4

High-throughput

0.553

High

1036849

SP4
Transcription factor Sp4

2

6

High-throughput

0.553

High

1036884

SP3
Transcription factor Sp3

2

6

High-throughput

0.553

High

1208299

ZN438
Zinc finger protein 438

2

2

High-throughput

0.553

High

1208304

YAF2
YY1-associated factor 2

2

1

High-throughput

0.553

High

1208305

ZN655
Zinc finger protein 655

2

2

High-throughput

0.553

High

1208308

BANP
Protein BANP

2

1

High-throughput

0.553

High

1208314

ZN526
Zinc finger protein 526

2

1

High-throughput

0.553

High

1208320

LMBL3
Lethal(3)malignant brain tumor-like protein 3

2

2

High-throughput

0.553

High

1208321

STAC3
SH3 and cysteine-rich domain-containing protein 3

2

1

High-throughput

0.553

High

1208322

ZN75A
Zinc finger protein 75A

2

6

High-throughput

0.553

High

1208327

ZNF2
Zinc finger protein 2

2

4

High-throughput

0.553

High

1208328

PBX4
Pre-B-cell leukemia transcription factor 4

2

1

High-throughput

0.553

High

1208340

SMBT1
Scm-like with four MBT domains protein 1

2

2

High-throughput

0.553

High

60192

ZN320
Zinc finger protein 320

1

4

High-throughput

0.489

High

158999

ZN195
Zinc finger protein 195

1

4

High-throughput

0.489

High

273264

T22D2
TSC22 domain family protein 2

1

1

High-throughput

0.489

High

317186

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

2

High-throughput

0.489

High

675531

TYY1
Transcriptional repressor protein YY1

1

6

High-throughput

0.489

High

923600

TTC3
E3 ubiquitin-protein ligase TTC3

1

1

High-throughput

0.489

High

1044419

ZNF92
Zinc finger protein 92

1

3

High-throughput

0.489

High

1195479

PLCH1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

1

1

High-throughput

0.489

High

1204608

BCORL
BCL-6 corepressor-like protein 1

1

4

High-throughput

0.489

High

1208309

RN214
RING finger protein 214

1

1

High-throughput

0.489

High

1208312

ARH40
Rho guanine nucleotide exchange factor 40

1

4

High-throughput

0.489

High

1208313

ZN431
Zinc finger protein 431

1

3

High-throughput

0.489

High

1208318

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

2

High-throughput

0.489

High

1208325

T22D3
TSC22 domain family protein 3

1

1

High-throughput

0.489

High

1208332

ZN430
Zinc finger protein 430

1

3

High-throughput

0.489

High

1208333

ECT2
Protein ECT2

1

2

High-throughput

0.489

High

1208335

WDR54
WD repeat-containing protein 54

1

1

High-throughput

0.489

High

1208345

WDR37
WD repeat-containing protein 37

1

2

High-throughput

0.489

High

1208292

Q6FHY5
MEOX2 protein

1

3

High-throughput

0.470

High

1208349

U3KQK0
Histone H2B

1

3

High-throughput

0.470

High

1208350

X5D778
Ankyrin repeat domain 11 isoform A

1

1

High-throughput

0.470

High

449729

H2B1J
Histone H2B type 1-J

1

3

High-throughput

0.439

High

893905

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.439

High

1162964

H2B2E
Histone H2B type 2-E

1

3

High-throughput

0.439

High

1208296

ANR11
Ankyrin repeat domain-containing protein 11

1

3

High-throughput

0.439

High

1208326

H2B1N
Histone H2B type 1-N

1

3

High-throughput

0.439

High

254380

CC14B
Dual specificity protein phosphatase CDC14B

2

0

High-throughput

0.316

High

619247

TNNI1
Troponin I, slow skeletal muscle

2

0

High-throughput

0.316

High

788678

SRP14
Signal recognition particle 14 kDa protein

2

0

High-throughput

0.316

High

799925

COIL
Coilin

2

0

High-throughput

0.316

High

903053

ZNF84
Zinc finger protein 84

2

0

High-throughput

0.316

High

940136

RRP1
Ribosomal RNA processing protein 1 homolog A

2

0

High-throughput

0.316

High

974576

SMD2
Small nuclear ribonucleoprotein Sm D2

2

0

High-throughput

0.316

High

1146276

ANKR1
Ankyrin repeat domain-containing protein 1

2

0

High-throughput

0.316

High

1160481

SMN
Survival motor neuron protein

2

0

High-throughput

0.316

High

1200122

BOREA
Borealin

2

0

High-throughput

0.316

High

1208291

VAX1
Ventral anterior homeobox 1

2

0

High-throughput

0.316

High

1208295

GASP3
G protein-coupled receptor associated sorting protein 3

2

0

High-throughput

0.316

High

1208298

DPPA4
Developmental pluripotency-associated protein 4

2

0

High-throughput

0.316

High

1208300

KHDC4
KH homology domain-containing protein 4

2

0

High-throughput

0.316

High

1208301

BIVM
Basic immunoglobulin-like variable motif-containing protein

2

0

High-throughput

0.316

High

1208306

BEND7
BEN domain-containing protein 7

2

0

High-throughput

0.316

High

1208307

CDYL2
Chromodomain Y-like protein 2

2

0

High-throughput

0.316

High

1208310

SNIP1
Smad nuclear-interacting protein 1

2

0

High-throughput

0.316

High

1208319

SYTL4
Synaptotagmin-like protein 4

2

0

High-throughput

0.316

High

1208324

F193B
Protein FAM193B

2

0

High-throughput

0.316

High

1208331

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.316

High

1208334

F204A
Protein FAM204A

2

0

High-throughput

0.316

High

1208336

KRCC1
Lysine-rich coiled-coil protein 1

2

0

High-throughput

0.316

High

1208337

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1208338

THAP1
THAP domain-containing protein 1

2

0

High-throughput

0.316

High

1208339

NOL12
Nucleolar protein 12

2

0

High-throughput

0.316

High

1208346

E41L3
Band 4.1-like protein 3

2

0

High-throughput

0.316

High

213614

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.279

Low

287945

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.279

Low

302225

S14L2
SEC14-like protein 2

1

0

High-throughput

0.279

Low

542543

TOP2A
DNA topoisomerase 2-alpha

1

0

High-throughput

0.279

Low

885802

KC1E
Casein kinase I isoform epsilon

1

0

High-throughput

0.279

Low

1085759

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.279

Low

1151320

ZNHI3
Zinc finger HIT domain-containing protein 3

1

0

High-throughput

0.279

Low

1208293

PHLB3
Pleckstrin homology-like domain family B member 3

1

0

High-throughput

0.279

Low

1208297

PACS1
Phosphofurin acidic cluster sorting protein 1

1

0

High-throughput

0.279

Low

1208302

C2CD5
C2 domain-containing protein 5

1

0

High-throughput

0.279

Low

1208303

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.279

Low

1208311

ALMS1
Centrosome-associated protein ALMS1

1

0

High-throughput

0.279

Low

1208315

TF3C2
General transcription factor 3C polypeptide 2

1

0

High-throughput

0.279

Low

1208316

BBX
HMG box transcription factor BBX

1

0

High-throughput

0.279

Low

1208317

TF3C6
General transcription factor 3C polypeptide 6

1

0

High-throughput

0.279

Low

1208323

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

1

0

High-throughput

0.279

Low

1208329

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.279

Low

1208330

TSYL1
Testis-specific Y-encoded-like protein 1

1

0

High-throughput

0.279

Low

1208341

NUFP1
FMR1-interacting protein NUFIP1

1

0

High-throughput

0.279

Low

1208342

NRBP
Nuclear receptor-binding protein

1

0

High-throughput

0.279

Low

1208343

DACH1
Dachshund homolog 1

1

0

High-throughput

0.279

Low

1208344

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

0

High-throughput

0.279

Low

1208347

TF3C5
General transcription factor 3C polypeptide 5

1

0

High-throughput

0.279

Low

1208348

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.279

Low

889289

NUMB
Protein numb homolog

1

0

High-throughput

0.251

Low

961313

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.251

Low

251308

NEMF
Ribosome quality control complex subunit NEMF

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025