HitPredict

Interactor 1: ANM5 (Q8CIG8)
Protein arginine N-methyltransferase 5 (Prmt5) (EC 2.1.1.320) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog)
Gene: Prmt5

Interactor 2: MEP50 (Q99J09)
Methylosome protein WDR77 (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77)
Gene: Wdr77

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.759

The method score is based on:

Property Details
Experiments 30675521, 20951943
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PRMT5_TIM~WD40
Common GO terms GO:0000387 - spliceosomal snRNP assembly
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 637
Mm

1 342
+ Hs
+ Hs
+ Xl
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp

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Last updated: 15 Jul 2024