Protein: SMAG2
Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B)

Gene: SMAG2, SAMD4B
Organism: Homo sapiens
Interactions: 120
UniProt ID: Q5PRF9

Gene Ontology (top 5):
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1208605

SMAG1
Protein Smaug homolog 1

2

1

High-throughput

0.811

High

187359

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

2

1

High-throughput

0.789

High

729904

1433B
14-3-3 protein beta/alpha

9

20

High-throughput

0.754

High

966420

1433G
14-3-3 protein gamma

7

20

High-throughput

0.749

High

691081

1433T
14-3-3 protein theta

8

20

High-throughput

0.748

High

990310

1433Z
14-3-3 protein zeta/delta

6

20

High-throughput

0.732

High

971607

1433E
14-3-3 protein epsilon

5

1

High-throughput

0.718

High

1049373

1433F
14-3-3 protein eta

4

20

High-throughput

0.697

High

1208538

SMAG2
Protein Smaug homolog 2

1

1

High-throughput

0.621

High

1208563

RENT1
Regulator of nonsense transcripts 1

2

1

High-throughput

0.611

High

977719

ACTA
Actin, aortic smooth muscle

2

0

High-throughput

0.602

High

1151990

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

0

High-throughput

0.586

High

1208577

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

0

High-throughput

0.586

High

1208587

PDLI7
PDZ and LIM domain protein 7

1

0

High-throughput

0.586

High

1208596

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.586

High

1208606

GRIP1
Glutamate receptor-interacting protein 1

1

0

High-throughput

0.586

High

1208548

RSRC2
Arginine/serine-rich coiled-coil protein 2

2

0

High-throughput

0.580

High

1208584

B2L10
Bcl-2-like protein 10

2

0

High-throughput

0.580

High

1208594

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

2

1

High-throughput

0.574

High

396272

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

208676

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

1

High-throughput

0.553

High

1208595

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

1

High-throughput

0.553

High

563876

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

872404

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

1208552

NUTM1
NUT family member 1

1

1

High-throughput

0.481

High

64032

CNOT1
CCR4-NOT transcription complex subunit 1

1

1

High-throughput

0.479

High

172904

XPO1
Exportin-1

1

4

High-throughput

0.479

High

176487

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.479

High

258919

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.479

High

273875

CNOT3
CCR4-NOT transcription complex subunit 3

1

1

High-throughput

0.479

High

727836

DNJA1
DnaJ homolog subfamily A member 1

1

1

High-throughput

0.479

High

730643

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

1165448

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

2

High-throughput

0.479

High

1208549

YTHD3
YTH domain-containing family protein 3

1

1

High-throughput

0.479

High

1208553

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

1

High-throughput

0.479

High

1208560

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.479

High

1208562

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1208567

FUBP3
Far upstream element-binding protein 3

1

2

High-throughput

0.479

High

1208582

MOV10
Helicase MOV-10

1

1

High-throughput

0.479

High

1208589

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

2

High-throughput

0.479

High

1208591

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

2

High-throughput

0.479

High

1208592

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1208593

CNOT2
CCR4-NOT transcription complex subunit 2

1

1

High-throughput

0.479

High

1208597

CNOT7
CCR4-NOT transcription complex subunit 7

1

1

High-throughput

0.479

High

1208598

AGO2
Protein argonaute-2

1

4

High-throughput

0.479

High

1208600

AGO1
Protein argonaute-1

1

5

High-throughput

0.479

High

1208604

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

1

High-throughput

0.479

High

1208608

YTHD2
YTH domain-containing family protein 2

1

1

High-throughput

0.479

High

1208609

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

2

High-throughput

0.479

High

135945

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

0

High-throughput

0.458

High

164583

TNPO2
Transportin-2

1

0

High-throughput

0.458

High

175072

SC16A
Protein transport protein Sec16A

1

0

High-throughput

0.458

High

213158

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.458

High

214583

WDR62
WD repeat-containing protein 62

1

0

High-throughput

0.458

High

315669

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

324144

CE152
Centrosomal protein of 152 kDa

1

0

High-throughput

0.458

High

352458

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

472797

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

540030

BCR
Breakpoint cluster region protein

1

0

High-throughput

0.458

High

668619

APC
Adenomatous polyposis coli protein

1

0

High-throughput

0.458

High

688257

TTP
mRNA decay activator protein ZFP36

1

0

High-throughput

0.458

High

695645

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

830873

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

1085570

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

1129417

PUM1
Pumilio homolog 1

1

0

High-throughput

0.458

High

1178583

KIF7
Kinesin-like protein KIF7

1

0

High-throughput

0.458

High

1198331

CRTC2
CREB-regulated transcription coactivator 2

1

0

High-throughput

0.458

High

1201679

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

0

High-throughput

0.458

High

1206461

PRC2B
Protein PRRC2B

1

0

High-throughput

0.458

High

1208539

CE350
Centrosome-associated protein 350

1

0

High-throughput

0.458

High

1208540

DEN4C
DENN domain-containing protein 4C

1

0

High-throughput

0.458

High

1208542

CEP85
Centrosomal protein of 85 kDa

1

0

High-throughput

0.458

High

1208544

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

1208550

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.458

High

1208558

ALMS1
Centrosome-associated protein ALMS1

1

0

High-throughput

0.458

High

1208561

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

1208566

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.458

High

1208569

CEP89
Centrosomal protein of 89 kDa

1

0

High-throughput

0.458

High

1208570

SEBP2
Selenocysteine insertion sequence-binding protein 2

1

0

High-throughput

0.458

High

1208572

LZTS2
Leucine zipper putative tumor suppressor 2

1

0

High-throughput

0.458

High

1208575

OSBL3
Oxysterol-binding protein-related protein 3

1

0

High-throughput

0.458

High

1208576

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1208578

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

1208580

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.458

High

1208581

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1208586

DCP1A
mRNA-decapping enzyme 1A

1

0

High-throughput

0.458

High

1208588

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

1208590

MKS1
Tectonic-like complex member MKS1

1

0

High-throughput

0.458

High

1208599

CNO11
CCR4-NOT transcription complex subunit 11

1

0

High-throughput

0.458

High

1208601

PKHG1
Pleckstrin homology domain-containing family G member 1

1

0

High-throughput

0.458

High

1208602

CP131
Centrosomal protein of 131 kDa

1

0

High-throughput

0.458

High

1208603

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

0

High-throughput

0.458

High

1208607

MARF1
Meiosis regulator and mRNA stability factor 1

1

0

High-throughput

0.458

High

1208547

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.445

High

106071

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

1033367

CDR2
Cerebellar degeneration-related protein 2

1

1

High-throughput

0.437

High

1208545

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1208551

CDR2L
Cerebellar degeneration-related protein 2-like

1

1

High-throughput

0.437

High

1208559

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.437

High

1208574

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

0

Small-scale

0.426

High

116359

CC179
Coiled-coil domain-containing protein 179

2

0

High-throughput

0.316

High

1208541

LRC8E
Volume-regulated anion channel subunit LRRC8E

2

0

High-throughput

0.316

High

1208546

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

2

0

High-throughput

0.316

High

1208564

RGMA
Repulsive guidance molecule A

1

0

High-throughput

0.279

Low

67771

TBKB1
TANK-binding kinase 1-binding protein 1

1

0

High-throughput

0.249

Low

1004267

F193A
Protein FAM193A

1

0

High-throughput

0.249

Low

1168996

CSPP1
Centrosome and spindle pole-associated protein 1

1

0

High-throughput

0.249

Low

1208543

SYNE3
Nesprin-3

1

0

High-throughput

0.249

Low

1208554

NIN
Ninein

1

0

High-throughput

0.249

Low

1208555

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1208556

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

1

0

High-throughput

0.249

Low

1208557

NAV1
Neuron navigator 1

1

0

High-throughput

0.249

Low

1208565

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low

1208568

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.249

Low

1208571

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.249

Low

1208573

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.249

Low

1208579

CCSE2
Serine-rich coiled-coil domain-containing protein 2

1

0

High-throughput

0.249

Low

1208583

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.249

Low

1208585

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025