HitPredict

Interactor 1: TAD2B (Q8I8V0)
Transcriptional adapter 2B (dADA2b)
Gene: Ada2b

Interactor 2: Q9VTZ1 (Q9VTZ1)
Histone acetyltransferase GCN5 (EC 2.3.1.48)
Gene: Gcn5

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.981

Property	Details
Experiments	20008933, 21764853, 12482983, 12697829, 18188155, 30559249, 30715476, 29995556, 17030603, 16428443, 15340070, 18034162, 19947544, 14605208
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Acetyltransf_1~Myb_DNA-binding
Common GO terms	GO:0000124 - SAGA complex GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005700 - polytene chromosome GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 555 Dm			1 813
+	Dm
		283714 TAD2B_DROME (1-555): 0: 680: 100.00		O76216_DROME (1-813): 0: 1138: 99.63
+	Hs
		1198566 TAD2B_HUMAN (4-412): 4.6e-142: 418: 36.39		KAT2B_HUMAN (71-813): 0: 1026: 47.27
+	Dm
		1181824 TAD2A_DROME (13-367): 1.76e-92: 296: 24.35		Q9VTZ1_DROME (1-813): 0: 1141: 100.00
+	Dm
		283712 TAD2A_DROME (13-367): 1.76e-92: 296: 24.35		O76216_DROME (1-813): 0: 1138: 99.63
+	Hs
		1198565 TAD2B_HUMAN (4-412): 4.6e-142: 418: 36.39		KAT2A_HUMAN (58-813): 0: 1014: 47.23
+	Mm
		1208540 TAD2A_MOUSE (6-412): 5.14e-110: 337: 23.56		KAT2B_MOUSE (35-813): 0: 1069: 44.82
+	Hs
		266399 TAD2A_HUMAN (6-412): 2.74e-111: 340: 23.56		KAT2B_HUMAN (71-813): 0: 1026: 47.27
+	Mm
		1208541 TAD2A_MOUSE (6-412): 5.14e-110: 337: 23.56		KAT2A_MOUSE (61-813): 0: 1020: 47.40
+	Hs
		266398 TAD2A_HUMAN (6-412): 2.74e-111: 340: 23.56		KAT2A_HUMAN (58-813): 0: 1014: 47.23
+	Sc
		970392 ADA2_YEAST (7-412): 3.3e-122: 368: 23.06		GCN5_YEAST (398-811): 1.24e-165: 488: 37.68
+	At
		1308007 TAD2B_ARATH (1-410): 3.98e-114: 349: 23.54		GCN5_ARATH (453-806): 3.2e-149: 451: 42.03
+	At
		1308015 TAD2A_ARATH (11-410): 6.47e-83: 270: 17.79		GCN5_ARATH (453-806): 3.2e-149: 451: 42.03
+	Sc
		797934 RSC8_YEAST (6-285): 2.4e-48: 178: 14.53		GCN5_YEAST (398-811): 1.24e-165: 488: 37.68
+	Sc
		696166 SWI3_YEAST (59-375): 2.6e-44: 170: 12.88		GCN5_YEAST (398-811): 1.24e-165: 488: 37.68
+	At
		1275616 SWI3C_ARATH (12-289): 9.27e-40: 156: 15.89		GTE11_ARATH (623-810): 2.98e-39: 156: 21.33
+	At
		1195144 SWI3B_ARATH (2-258): 1.42e-40: 155: 13.79		GTE11_ARATH (623-810): 2.98e-39: 156: 21.33
+	Sc
		728711 RSC8_YEAST (6-285): 2.4e-48: 178: 14.53		BDF1_YEAST (640-812): 2.1e-22: 104: 20.57
+	Hs
		998902 SMRC2_HUMAN (49-256): 5.79e-26: 114: 9.52		EP300_HUMAN (614-805): 7.86e-38: 155: 20.51
+	Hs
		631516 SMRC2_HUMAN (49-256): 5.79e-26: 114: 9.52		BRD2_HUMAN (639-809): 2.01e-34: 143: 21.98
+	Hs
		244684 SMRC2_HUMAN (49-256): 5.79e-26: 114: 9.52		BRD4_HUMAN (636-809): 9.67e-31: 132: 21.11