HitPredict

Interactor 1: TPC3L (Q5T215)
Trafficking protein particle complex subunit 3-like protein (TRAPPC3-like protein) (BET3-like protein)
Gene: TRAPPC3L

Interactor 2: TPC6B (Q86SZ2)
Trafficking protein particle complex subunit 6B (TRAPP complex subunit 6B)
Gene: TRAPPC6B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21525244
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	TRAPP~TRAPP
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0030008 - TRAPP complex
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 181 Hs			1 158
+	Hs
		221742 TPPC3_HUMAN (1-181): 2.99e-105: 301: 61.88		TPC6B_HUMAN (1-158): 2.35e-75: 223: 100.00
+	Hs
		221702 TPPC3_HUMAN (1-181): 2.99e-105: 301: 61.88		TPC6A_HUMAN (1-157): 4.14e-65: 197: 56.33
+	Hs
		295983 TPC3L_HUMAN (1-181): 8.88e-103: 294: 100.00		TPC6A_HUMAN (1-157): 4.14e-65: 197: 56.33
+	Dm
		1473642 Q9VSY8_DROME (1-181): 1.3e-89: 261: 46.41		Q9VF82_DROME (1-157): 4.37e-64: 194: 53.50
+	Hs
		221744 TPPC3_HUMAN (1-181): 2.99e-105: 301: 61.88		TPPC5_HUMAN (5-141): 5.37e-41: 137: 19.72
+	Mm
		237006 TPPC3_MOUSE (1-181): 5.72e-105: 300: 61.33		TPPC5_MOUSE (5-141): 5.03e-41: 137: 19.72
+	Hs
		1212062 TPC3L_HUMAN (1-181): 8.88e-103: 294: 100.00		TPPC5_HUMAN (5-141): 5.37e-41: 137: 19.72
+	Dm
		1265448 Q9VSY8_DROME (1-181): 1.3e-89: 261: 46.41		Q7K2Q8_DROME (4-141): 2.79e-42: 140: 20.98
+	At
		1424799 Q9FFV2_ARATH (13-177): 2.74e-87: 255: 50.30		Q9FGU1_ARATH (7-141): 2.96e-42: 140: 24.29
+	Sc
		782250 BET3_YEAST (10-181): 1.31e-86: 254: 46.82		TRS33_YEAST (14-137): 1.03e-35: 126: 37.59
+	Ce
		759714 TPPC3_CAEEL (8-181): 7.89e-68: 206: 39.55		Q9XU81_CAEEL (17-156): 1.76e-54: 171: 47.86
+	Sc
		782241 BET3_YEAST (10-181): 1.31e-86: 254: 46.82		TRS31_YEAST (47-141): 1.43e-27: 105: 32.99
+	Ce
		759712 TPPC3_CAEEL (8-181): 7.89e-68: 206: 39.55		Q9NA81_CAEEL (5-141): 1.64e-41: 138: 23.24