Protein: TPPC3
Trafficking protein particle complex subunit 3 (BET3 homolog)

Gene: TPPC3, TRAPPC3
Organism: Homo sapiens
Interactions: 73
UniProt ID: O43617

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

221764

TPC2L
Trafficking protein particle complex subunit 2-like protein

9

10

Small-scale

0.975

High

221770

TPPC1
Trafficking protein particle complex subunit 1

9

9

Small-scale

0.971

High

221702

TPC6A
Trafficking protein particle complex subunit 6A

8

13

Small-scale

0.970

High

221744

TPPC5
Trafficking protein particle complex subunit 5

5

13

Small-scale

0.927

High

221711

TPC2B
Trafficking protein particle complex subunit 2B

5

10

Small-scale

0.907

High

221742

TPC6B
Trafficking protein particle complex subunit 6B

4

13

Small-scale

0.882

High

221710

TPC2A
Trafficking protein particle complex subunit 2

2

10

High-throughput

0.759

High

221766

TPPC4
Trafficking protein particle complex subunit 4

2

8

High-throughput

0.754

High

221750

TPC12
Trafficking protein particle complex subunit 12

4

2

High-throughput

0.694

High

221758

B2L14
Apoptosis facilitator Bcl-2-like protein 14

4

0

High-throughput

0.670

High

221740

TPC11
Trafficking protein particle complex subunit 11

3

2

Small-scale

0.656

High

221754

TPPC9
Trafficking protein particle complex subunit 9

3

4

Small-scale

0.640

High

221735

KANK4
KN motif and ankyrin repeat domain-containing protein 4

3

0

High-throughput

0.634

High

221717

BGAL
Beta-galactosidase

2

0

High-throughput

0.602

High

221759

STMN4
Stathmin-4

2

0

High-throughput

0.602

High

221762

TBC14
TBC1 domain family member 14

2

0

High-throughput

0.602

High

221755

RAB3I
Rab-3A-interacting protein

2

1

Small-scale

0.601

High

221768

TPPC8
Trafficking protein particle complex subunit 8

2

1

Small-scale

0.601

High

221705

EGFR
Epidermal growth factor receptor

2

1

High-throughput

0.584

High

221723

TPC10
Trafficking protein particle complex subunit 10

2

4

High-throughput

0.584

High

63847

TPC13
Trafficking protein particle complex subunit 13

2

0

Small-scale

0.576

High

221760

PKHF2
Pleckstrin homology domain-containing family F member 2

1

0

High-throughput

0.549

High

221719

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.536

High

221706

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.513

High

221736

C102B
Coiled-coil domain-containing protein 102B

1

0

High-throughput

0.513

High

221745

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

221765

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.513

High

221767

AMOL2
Angiomotin-like protein 2

1

0

High-throughput

0.513

High

221769

MTL5
Tesmin

1

0

High-throughput

0.513

High

221738

RUFY4
RUN and FYVE domain-containing protein 4

1

1

High-throughput

0.489

High

221743

RAB43
Ras-related protein Rab-43

1

2

High-throughput

0.489

High

221708

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

221728

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

221749

R3GEF
Guanine nucleotide exchange factor for Rab-3A

1

1

High-throughput

0.479

High

221700

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

221703

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

221707

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

221712

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

221713

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

221714

FGFR1
Fibroblast growth factor receptor 1

1

0

High-throughput

0.458

High

221721

PYR1
Multifunctional protein CAD

1

0

High-throughput

0.458

High

221724

FAS
Fatty acid synthase

1

0

High-throughput

0.458

High

221726

ST1A2
Sulfotransferase 1A2

1

0

High-throughput

0.458

High

221727

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

221731

NFAC3
Nuclear factor of activated T-cells, cytoplasmic 3

1

0

High-throughput

0.458

High

221733

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

221734

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

221739

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

221741

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

221751

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

221761

PDLI7
PDZ and LIM domain protein 7

1

0

High-throughput

0.458

High

221763

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

221715

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.437

High

221729

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

221747

M21D2
Nucleotidyltransferase MB21D2

1

1

High-throughput

0.437

High

221748

TM102
Transmembrane protein 102

1

1

High-throughput

0.437

High

221732

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.426

High

221725

DNLI4
DNA ligase 4

1

0

High-throughput

0.288

High

221701

CDC45
Cell division control protein 45 homolog

1

0

High-throughput

0.282

High

221718

HXB6
Homeobox protein Hox-B6

1

0

High-throughput

0.279

Low

217557

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

221704

LYPD3
Ly6/PLAUR domain-containing protein 3

1

0

High-throughput

0.249

Low

221709

INSR
Insulin receptor

1

0

High-throughput

0.249

Low

221716

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

221720

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

221722

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

221737

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

221753

CABS1
Calcium-binding and spermatid-specific protein 1

1

0

High-throughput

0.249

Low

221756

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

221757

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.249

Low

221730

LG3BP
Galectin-3-binding protein

1

0

High-throughput

0.232

Low

221746

CI040
Uncharacterized protein C9orf40

1

0

High-throughput

0.232

Low

221752

LDAF1
Lipid droplet assembly factor 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025