HitPredict

Interactor 1: PANG2 (Q8IMA8)
Protein pangolin, isoform J (dTCF)
Gene: pan

Interactor 2: Q9VUD3 (Q9VUD3)
GH07353p (Sox21b, isoform A) (Sox21b, isoform B)
Gene: Sox21b

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	30995488
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HMG_box~HMG_box
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1192 Dm			1 571
+	Dm
		1212946 PANG2_DROME (1-1192): 0: 1591: 100.00		PANG2_DROME (74-451): 2.98e-45: 174: 12.72
+	Dm
		114457 PANG1_DROME (589-1192): 1.32e-166: 514: 83.96		M9PCG2_DROME (1-571): 5.02e-92: 295: 100.00
+	Dm
		954936 PANG1_DROME (589-1192): 1.32e-166: 514: 83.96		PANG1_DROME (75-451): 1.57e-43: 167: 13.20
+	Hs
		881829 SOX10_HUMAN (634-1044): 8.64e-64: 226: 16.60		HM20A_HUMAN (143-403): 7.69e-39: 147: 14.07
+	Hs
		817845 SOX8_HUMAN (608-1044): 2.71e-67: 236: 14.13		SOX2_HUMAN (215-439): 1.19e-34: 135: 37.28
+	Hs
		881826 SOX10_HUMAN (634-1044): 8.64e-64: 226: 16.60		CIC_HUMAN (37-443): 1.18e-34: 142: 15.01
+	Hs
		818494 SOX2_HUMAN (681-989): 5.98e-51: 184: 13.52		TF7L2_HUMAN (29-453): 1.63e-42: 163: 12.99
+	Hs
		727836 SOX2_HUMAN (681-989): 5.98e-51: 184: 13.52		SOX6_HUMAN (230-411): 1.93e-40: 159: 28.50
+	Hs
		782193 SOX2_HUMAN (681-989): 5.98e-51: 184: 13.52		SOX3_HUMAN (244-361): 2.32e-38: 148: 59.32
+	Hs
		818487 SOX2_HUMAN (681-989): 5.98e-51: 184: 13.52		HM20A_HUMAN (143-403): 7.69e-39: 147: 14.07
+	Hs
		133761 SOX2_HUMAN (681-989): 5.98e-51: 184: 13.52		SOX1_HUMAN (242-321): 1.48e-36: 142: 82.50
+	Hs
		818373 SOX2_HUMAN (681-989): 5.98e-51: 184: 13.52		CIC_HUMAN (37-443): 1.18e-34: 142: 15.01
+	Hs
		313690 SOX2_HUMAN (681-989): 5.98e-51: 184: 13.52		SOX14_HUMAN (242-386): 3.31e-37: 139: 57.72
+	Hs
		881788 SOX10_HUMAN (634-1044): 8.64e-64: 226: 16.60		SOX10_HUMAN (243-322): 1.54e-20: 96.7: 60.00
+	Hs
		567658 SOX2_HUMAN (681-989): 5.98e-51: 184: 13.52		UBF1_HUMAN (208-507): 1.4e-33: 138: 12.91
+	Hs
		727709 SOX2_HUMAN (681-989): 5.98e-51: 184: 13.52		SOX5_HUMAN (25-382): 1.33e-33: 138: 20.88
+	Mm
		981835 SOX8_MOUSE (608-1044): 8.77e-51: 188: 12.98		Q60I23_MOUSE (215-439): 3.46e-34: 134: 37.72
+	Hs
		817782 SOX2_HUMAN (681-989): 5.98e-51: 184: 13.52		SOX2_HUMAN (215-439): 1.19e-34: 135: 37.28
+	Hs
		818669 SOX2_HUMAN (681-989): 5.98e-51: 184: 13.52		SOX21_HUMAN (242-373): 5.99e-34: 132: 60.90