Protein: RGS20
Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP) (Regulator of G-protein signaling Z1) (Regulator of Gz-selective protein signaling 1)

Gene: RGS20
Organism: Homo sapiens
Interactions: 122
UniProt ID: O76081

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005802 - trans-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

303120

RGS19
Regulator of G-protein signaling 19

2

5

High-throughput

0.789

High

303122

PLK1
Serine/threonine-protein kinase PLK1

2

1

High-throughput

0.789

High

303160

NEK8
Serine/threonine-protein kinase Nek8

2

3

High-throughput

0.783

High

303104

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

2

20

Small-scale

0.778

High

303125

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

20

Small-scale

0.740

High

303098

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

20

High-throughput

0.740

High

300077

GLRX3
Glutaredoxin-3

5

1

High-throughput

0.726

High

303108

OTX1
Homeobox protein OTX1

5

3

High-throughput

0.720

High

303166

CTSR1
Cation channel sperm-associated protein 1

4

2

High-throughput

0.703

High

303169

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

4

1

High-throughput

0.700

High

303127

CREB5
Cyclic AMP-responsive element-binding protein 5

3

3

High-throughput

0.675

High

303097

HRG
Histidine-rich glycoprotein

3

1

High-throughput

0.665

High

303109

TXLNA
Alpha-taxilin

3

4

High-throughput

0.662

High

303145

LCE1B
Late cornified envelope protein 1B

5

1

High-throughput

0.659

High

303102

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

1

20

Small-scale

0.647

High

303113

TNFL6
Tumor necrosis factor ligand superfamily member 6

3

0

High-throughput

0.646

High

303110

PE2R3
Prostaglandin E2 receptor EP3 subtype

2

11

High-throughput

0.628

High

303117

HXA1
Homeobox protein Hox-A1

2

7

High-throughput

0.628

High

303096

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.618

High

303105

KRA59
Keratin-associated protein 5-9

3

9

High-throughput

0.616

High

303140

LCE3E
Late cornified envelope protein 3E

3

5

High-throughput

0.616

High

303147

LCE4A
Late cornified envelope protein 4A

3

2

High-throughput

0.616

High

303155

KRA56
Keratin-associated protein 5-6

3

2

High-throughput

0.616

High

303186

KRA42
Keratin-associated protein 4-2

3

8

High-throughput

0.616

High

303200

CRCT1
Cysteine-rich C-terminal protein 1

3

1

High-throughput

0.616

High

176588

KIF3B
Kinesin-like protein KIF3B

2

5

High-throughput

0.611

High

303121

MRE11
Double-strand break repair protein MRE11

2

1

High-throughput

0.611

High

303134

CRY1
Cryptochrome-1

2

1

High-throughput

0.611

High

303153

CPIN1
Anamorsin

2

1

High-throughput

0.611

High

303161

TTC7B
Tetratricopeptide repeat protein 7B

2

1

High-throughput

0.611

High

303172

RAD50
DNA repair protein RAD50

2

6

High-throughput

0.611

High

303180

AASD1
Alanyl-tRNA editing protein Aarsd1

2

5

High-throughput

0.611

High

303183

HYCCI
Hyccin

2

1

High-throughput

0.611

High

303187

NEUL
Neurolysin, mitochondrial

2

1

High-throughput

0.611

High

303189

ZY11B
Protein zyg-11 homolog B

2

1

High-throughput

0.611

High

303198

MIOS
GATOR2 complex protein MIOS

2

1

High-throughput

0.611

High

303206

KIF3A
Kinesin-like protein KIF3A

2

5

High-throughput

0.611

High

303099

PPB1
Alkaline phosphatase, placental type

2

1

High-throughput

0.606

High

303152

VASN
Vasorin

2

3

High-throughput

0.606

High

303159

NUFP2
FMR1-interacting protein NUFIP2

2

2

High-throughput

0.606

High

303167

LNX1
E3 ubiquitin-protein ligase LNX

2

6

High-throughput

0.606

High

303171

NECT2
Nectin-2

2

2

High-throughput

0.606

High

303205

BOLA1
BolA-like protein 1

3

2

High-throughput

0.604

High

246210

MABP1
Mitogen-activated protein kinase-binding protein 1

1

2

High-throughput

0.573

High

303107

AQP1
Aquaporin-1

1

1

High-throughput

0.573

High

303136

KLH38
Kelch-like protein 38

1

2

High-throughput

0.573

High

303194

NECT3
Nectin-3

1

2

High-throughput

0.573

High

303114

MTR1A
Melatonin receptor type 1A

1

10

Small-scale

0.561

High

303118

PRI2
DNA primase large subunit

2

1

High-throughput

0.558

High

303176

MOCOS
Molybdenum cofactor sulfurase

2

1

High-throughput

0.558

High

303179

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

2

3

High-throughput

0.558

High

303181

SELO
Protein adenylyltransferase SelO, mitochondrial

2

1

High-throughput

0.558

High

303188

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

2

3

High-throughput

0.558

High

303195

TXLNG
Gamma-taxilin

2

4

High-throughput

0.558

High

303196

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

2

1

High-throughput

0.558

High

303201

NARF
Nuclear prelamin A recognition factor

2

3

High-throughput

0.558

High

159031

LCE2B
Late cornified envelope protein 2B

2

1

High-throughput

0.553

High

303139

LCE3C
Late cornified envelope protein 3C

2

1

High-throughput

0.553

High

303143

LCE1F
Late cornified envelope protein 1F

2

1

High-throughput

0.553

High

303144

LCE1A
Late cornified envelope protein 1A

2

1

High-throughput

0.553

High

303146

LCE3A
Late cornified envelope protein 3A

2

4

High-throughput

0.553

High

303149

LCE2C
Late cornified envelope protein 2C

2

4

High-throughput

0.553

High

303151

LCE5A
Late cornified envelope protein 5A

2

1

High-throughput

0.553

High

303154

KR511
Keratin-associated protein 5-11

2

10

High-throughput

0.553

High

303182

LCE3D
Late cornified envelope protein 3D

2

5

High-throughput

0.553

High

303184

KRA98
Keratin-associated protein 9-8

2

8

High-throughput

0.553

High

303185

KRA93
Keratin-associated protein 9-3

2

8

High-throughput

0.553

High

303138

DCA10
DDB1- and CUL4-associated factor 10

1

5

High-throughput

0.553

High

303119

HINT1
Adenosine 5'-monophosphoramidase HINT1

1

2

Small-scale

0.552

High

303103

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.549

High

303128

KIF1A
Kinesin-like protein KIF1A

1

5

High-throughput

0.541

High

303100

JUN
Transcription factor Jun

1

3

High-throughput

0.536

High

303148

LCE2A
Late cornified envelope protein 2A

1

3

High-throughput

0.523

High

303150

LCE2D
Late cornified envelope protein 2D

1

4

High-throughput

0.523

High

303126

SET
Protein SET

1

2

High-throughput

0.515

High

303133

MLF2
Myeloid leukemia factor 2

1

1

High-throughput

0.515

High

303115

IREB2
Iron-responsive element-binding protein 2

1

0

High-throughput

0.513

High

303124

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

0

High-throughput

0.513

High

303163

HID1
Protein HID1

1

0

High-throughput

0.513

High

303177

IFT43
Intraflagellar transport protein 43 homolog

1

0

High-throughput

0.513

High

303199

DPP3
Dipeptidyl peptidase 3

1

0

High-throughput

0.513

High

303173

STMN2
Stathmin-2

1

1

Small-scale

0.501

High

303116

MTR1B
Melatonin receptor type 1B

1

10

Small-scale

0.500

High

303112

NSF
Vesicle-fusing ATPase

1

0

High-throughput

0.493

High

303202

TR112
Multifunctional methyltransferase subunit TRM112-like protein

1

0

High-throughput

0.493

High

303203

RUVB2
RuvB-like 2

1

0

High-throughput

0.493

High

303178

AB17A
Alpha/beta hydrolase domain-containing protein 17A

1

0

High-throughput

0.486

High

303095

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.481

High

303101

ADRB2
Beta-2 adrenergic receptor

1

8

Small-scale

0.481

High

303141

LCE1D
Late cornified envelope protein 1D

1

1

High-throughput

0.481

High

303168

TBC16
TBC1 domain family member 16

1

2

High-throughput

0.481

High

303192

RANB3
Ran-binding protein 3

1

2

High-throughput

0.481

High

64702

PGP
Glycerol-3-phosphate phosphatase

1

2

High-throughput

0.479

High

261986

NBN
Nibrin

1

1

High-throughput

0.479

High

303094

ABL1
Tyrosine-protein kinase ABL1

1

3

High-throughput

0.479

High

303111

CRK
Adapter molecule crk

1

4

High-throughput

0.479

High

303129

TARB1
tRNA

1

1

High-throughput

0.479

High

303131

EFR3A
Protein EFR3 homolog A

1

3

High-throughput

0.479

High

303158

TRM1L
tRNA

1

1

High-throughput

0.479

High

303164

ZN444
Zinc finger protein 444

1

7

High-throughput

0.479

High

303165

ZN664
Zinc finger protein 664

1

4

High-throughput

0.479

High

303174

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.479

High

303193

ZN696
Zinc finger protein 696

1

4

High-throughput

0.479

High

303204

EFR3B
Protein EFR3 homolog B

1

3

High-throughput

0.479

High

303170

S39A7
Zinc transporter SLC39A7

1

2

High-throughput

0.470

High

46773

A0A384ME25
Epididymis secretory sperm binding protein

1

1

High-throughput

0.470

High

116808

I3WAC9
Insulin

1

1

High-throughput

0.470

High

303197

Q9NWL9
cDNA FLJ20748 fis, clone HEP05772

1

1

High-throughput

0.470

High

303142

LCE1E
Late cornified envelope protein 1E

1

1

High-throughput

0.439

High

303156

KRA54
Keratin-associated protein 5-4

1

10

High-throughput

0.439

High

303157

KRA53
Keratin-associated protein 5-3

1

10

High-throughput

0.439

High

303162

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

2

Small-scale

0.439

High

303190

NIF3L
NIF3-like protein 1

1

0

High-throughput

0.438

High

303123

ALR
FAD-linked sulfhydryl oxidase ALR

1

1

High-throughput

0.437

High

303130

CUL2
Cullin-2

1

3

High-throughput

0.437

High

303135

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

1

High-throughput

0.437

High

303137

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

1

High-throughput

0.437

High

303191

CIAO3
Cytosolic iron-sulfur assembly component 3

1

3

High-throughput

0.437

High

303106

CO8A1
Collagen alpha-1(VIII) chain

3

0

High-throughput

0.339

High

184780

SPTC1
Serine palmitoyltransferase 1

1

0

High-throughput

0.269

Low

303132

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.269

Low

303175

FAF2
FAS-associated factor 2

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025