Protein: LCE3D
Late cornified envelope protein 3D (Late envelope protein 16) (Small proline-rich-like epidermal differentiation complex protein 6A) (Small proline-rich-like epidermal differentiation complex protein 6B)

Gene: LCE3D
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q9BYE3

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0031424 - keratinization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

950877

KR109
Keratin-associated protein 10-9

3

20

High-throughput

0.654

High

221393

SPY1
Protein sprouty homolog 1

2

6

High-throughput

0.615

High

159088

LCE2B
Late cornified envelope protein 2B

2

1

High-throughput

0.606

High

221430

SPY3
Protein sprouty homolog 3

2

6

High-throughput

0.606

High

685936

KRA59
Keratin-associated protein 5-9

2

20

High-throughput

0.606

High

949618

KR123
Keratin-associated protein 12-3

2

2

High-throughput

0.606

High

950388

KR107
Keratin-associated protein 10-7

2

20

High-throughput

0.606

High

950657

KR108
Keratin-associated protein 10-8

2

20

High-throughput

0.606

High

1059730

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.606

High

1146146

K1H1
Keratin, type I cuticular Ha1

2

3

High-throughput

0.606

High

1215193

LCE2C
Late cornified envelope protein 2C

2

4

High-throughput

0.606

High

1235808

KRA57
Keratin-associated protein 5-7

2

20

High-throughput

0.606

High

1235843

KRA56
Keratin-associated protein 5-6

2

2

High-throughput

0.606

High

1235895

KRA53
Keratin-associated protein 5-3

2

20

High-throughput

0.606

High

1307445

KRA13
Keratin-associated protein 1-3

2

20

High-throughput

0.606

High

1410091

KR412
Keratin-associated protein 4-12

2

20

High-throughput

0.606

High

1418370

KR171
Keratin-associated protein 17-1

2

1

High-throughput

0.606

High

1418371

KRA98
Keratin-associated protein 9-8

2

20

High-throughput

0.606

High

1418372

KRA93
Keratin-associated protein 9-3

2

20

High-throughput

0.606

High

1418373

KRA92
Keratin-associated protein 9-2

2

20

High-throughput

0.606

High

1418375

KRA41
Keratin-associated protein 4-1

2

20

High-throughput

0.606

High

1418376

KRA45
Keratin-associated protein 4-5

2

20

High-throughput

0.606

High

1418378

KRA42
Keratin-associated protein 4-2

2

20

High-throughput

0.606

High

1418379

KRA33
Keratin-associated protein 3-3

2

6

High-throughput

0.606

High

1418380

KRA32
Keratin-associated protein 3-2

2

6

High-throughput

0.606

High

1418381

KRA31
Keratin-associated protein 3-1

2

6

High-throughput

0.606

High

1418383

KRA15
Keratin-associated protein 1-5

2

20

High-throughput

0.606

High

877609

CCN3
CCN family member 3

2

0

High-throughput

0.580

High

1407077

MDFI
MyoD family inhibitor

2

2

High-throughput

0.561

High

70455

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.553

High

165191

TSN4
Tetraspanin-4

2

1

High-throughput

0.553

High

303182

RGS20
Regulator of G-protein signaling 20

2

5

High-throughput

0.553

High

351599

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

2

5

High-throughput

0.553

High

426132

PPB1
Alkaline phosphatase, placental type

2

2

High-throughput

0.553

High

1022273

FBLN2
Fibulin-2

2

4

High-throughput

0.553

High

1086440

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

2

5

High-throughput

0.553

High

1180123

VWC2
Brorin

2

3

High-throughput

0.553

High

1213822

KPRP
Keratinocyte proline-rich protein

2

2

High-throughput

0.553

High

1250301

ATL4
ADAMTS-like protein 4

2

2

High-throughput

0.553

High

1311463

TRI42
Tripartite motif-containing protein 42

2

4

High-throughput

0.553

High

1369106

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

1

High-throughput

0.553

High

1418384

RGS17
Regulator of G-protein signaling 17

2

5

High-throughput

0.553

High

1418385

CHIC2
Cysteine-rich hydrophobic domain-containing protein 2

2

2

High-throughput

0.553

High

1006680

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.550

High

1402560

SRPK1
SRSF protein kinase 1

1

1

High-throughput

0.550

High

180916

TIF1A
Transcription intermediary factor 1-alpha

1

4

High-throughput

0.536

High

950119

KR105
Keratin-associated protein 10-5

1

20

High-throughput

0.515

High

1186798

KRA63
Keratin-associated protein 6-3

1

2

High-throughput

0.515

High

1418382

KRA24
Keratin-associated protein 2-4

1

20

High-throughput

0.515

High

505376

KRA23
Keratin-associated protein 2-3

1

20

High-throughput

0.481

High

949766

KR101
Keratin-associated protein 10-1

1

20

High-throughput

0.481

High

950200

KR106
Keratin-associated protein 10-6

1

20

High-throughput

0.481

High

1215152

LCE2A
Late cornified envelope protein 2A

1

3

High-throughput

0.481

High

1215227

LCE2D
Late cornified envelope protein 2D

1

4

High-throughput

0.481

High

1235773

KR511
Keratin-associated protein 5-11

1

20

High-throughput

0.481

High

1235870

KRA54
Keratin-associated protein 5-4

1

20

High-throughput

0.481

High

1257644

KRA52
Keratin-associated protein 5-2

1

2

High-throughput

0.481

High

1418374

KR411
Keratin-associated protein 4-11

1

20

High-throughput

0.481

High

1418377

KRA44
Keratin-associated protein 4-4

1

20

High-throughput

0.481

High

3415

A0A0S2Z4U3
Syndecan

1

1

High-throughput

0.470

High

517098

NT2NC
Notch homolog 2 N-terminal-like protein C

1

6

High-throughput

0.470

High

949675

KR124
Keratin-associated protein 12-4

1

0

High-throughput

0.460

High

1206962

CEP78
Centrosomal protein of 78 kDa

1

0

High-throughput

0.458

High

617

NBPFJ
NBPF family member NBPF19

1

2

High-throughput

0.439

High

74138

VWC2L
von Willebrand factor C domain-containing protein 2-like

1

2

High-throughput

0.439

High

269926

SDC3
Syndecan-3

1

1

High-throughput

0.439

High

475213

CP21A
Steroid 21-hydroxylase

1

2

High-throughput

0.439

High

885388

HXA1
Homeobox protein Hox-A1

1

2

High-throughput

0.439

High

1277381

NT2NA
Notch homolog 2 N-terminal-like protein A

1

6

High-throughput

0.439

High

1327723

MACOI
Macoilin

1

1

High-throughput

0.439

High

1418386

TRI33
E3 ubiquitin-protein ligase TRIM33

1

4

High-throughput

0.437

High

376904

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

2

0

High-throughput

0.316

High

1236153

TEN4
Teneurin-4

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025