HitPredict

Interactor 1: Q8IMX8 (Q8IMX8)
U6 snRNA-associated Sm-like protein LSm3
Gene: LSm3

Interactor 2: Q9VKW8 (Q9VKW8)
U6 snRNA-associated Sm-like protein LSm4
Gene: CG5356

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0000932 - P-body GO:0005688 - U6 snRNP GO:0033962 - P-body assembly GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Dm			1 154
+	Hs
		912211 LSM3_HUMAN (1-103): 4.31e-38: 125: 76.70		LSM4_HUMAN (1-88): 1.03e-40: 134: 88.64
+	Hs
		928049 RSMN_HUMAN (24-103): 3.91e-27: 101: 21.43		LSM4_HUMAN (1-88): 1.03e-40: 134: 88.64
+	Hs
		539204 RSMB_HUMAN (24-103): 1.27e-26: 99.7: 21.43		LSM4_HUMAN (1-88): 1.03e-40: 134: 88.64
+	Dm
		1213199 Q8IMX8_DROME (1-103): 1.85e-39: 128: 100.00		Q9VTW6_DROME (1-88): 2.16e-29: 104: 35.87
+	Hs
		912142 LSM3_HUMAN (1-103): 4.31e-38: 125: 76.70		SMD3_HUMAN (2-105): 3.32e-30: 107: 31.73
+	Hs
		912140 LSM3_HUMAN (1-103): 4.31e-38: 125: 76.70		SMD1_HUMAN (1-90): 1.1e-29: 106: 27.96
+	Hs
		912205 LSM3_HUMAN (1-103): 4.31e-38: 125: 76.70		LSM2_HUMAN (1-88): 2.35e-28: 102: 34.78
+	Hs
		912173 LSM3_HUMAN (1-103): 4.31e-38: 125: 76.70		LSM10_HUMAN (3-99): 4.67e-27: 99.7: 25.25
+	Hs
		911791 LSM3_HUMAN (1-103): 4.31e-38: 125: 76.70		RUXF_HUMAN (3-70): 7.41e-26: 95.5: 33.82
+	Hs
		912611 RSMN_HUMAN (24-103): 3.91e-27: 101: 21.43		SMD3_HUMAN (2-105): 3.32e-30: 107: 31.73
+	Hs
		912265 RSMN_HUMAN (24-103): 3.91e-27: 101: 21.43		SMD1_HUMAN (1-90): 1.1e-29: 106: 27.96
+	Hs
		538896 RSMB_HUMAN (24-103): 1.27e-26: 99.7: 21.43		SMD3_HUMAN (2-105): 3.32e-30: 107: 31.73
+	Hs
		538894 RSMB_HUMAN (24-103): 1.27e-26: 99.7: 21.43		SMD1_HUMAN (1-90): 1.1e-29: 106: 27.96
+	Hs
		928046 RSMN_HUMAN (24-103): 3.91e-27: 101: 21.43		LSM2_HUMAN (1-88): 2.35e-28: 102: 34.78
+	At
		1323437 Q9FI15_ARATH (24-100): 1.97e-27: 102: 28.75		SMD1B_ARATH (1-103): 1.63e-27: 100: 24.53
+	Hs
		539197 RSMB_HUMAN (24-103): 1.27e-26: 99.7: 21.43		LSM2_HUMAN (1-88): 2.35e-28: 102: 34.78
+	Sp
		293324 LSM3_SCHPO (10-99): 5.37e-30: 104: 60.00		LSM2_SCHPO (1-87): 2.07e-25: 94.7: 26.67
+	Hs
		911801 RSMN_HUMAN (24-103): 3.91e-27: 101: 21.43		RUXF_HUMAN (3-70): 7.41e-26: 95.5: 33.82
+	Sp
		223544 LSM3_SCHPO (10-99): 5.37e-30: 104: 60.00		RUXF_SCHPO (3-69): 1.48e-24: 92: 32.84
+	Hs
		538890 RSMB_HUMAN (24-103): 1.27e-26: 99.7: 21.43		RUXF_HUMAN (3-70): 7.41e-26: 95.5: 33.82