HitPredict

Interactor 1: LCE1E (Q5T753)
Late cornified envelope protein 1E (Late envelope protein 5)
Gene: LCE1E

Interactor 2: KRA98 (Q9BYQ0)
Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8)
Gene: KRTAP9-8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 118 Hs			1 159
+	Hs
		1214004 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KRA93_HUMAN (1-159): 1.93e-41: 137: 86.16
+	Hs
		1214005 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KRA92_HUMAN (1-159): 1.54e-36: 125: 77.59
+	Hs
		1059651 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KRA11_HUMAN (1-158): 8.28e-24: 93.2: 32.77
+	Hs
		1213992 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KRA13_HUMAN (1-153): 7.59e-23: 90.5: 34.13
+	Hs
		950069 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR105_HUMAN (7-159): 5.11e-21: 87.8: 21.89
+	Hs
		950275 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR107_HUMAN (5-159): 9.28e-17: 77.8: 23.33
+	Hs
		949653 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR124_HUMAN (20-116): 3.88e-15: 68.9: 30.93
+	Hs
		950782 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR109_HUMAN (2-130): 2.09e-13: 67.8: 25.64
+	Hs
		1214008 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KRA44_HUMAN (1-126): 1.51e-13: 66.2: 36.72
+	Hs
		950513 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR108_HUMAN (3-149): 7.64e-13: 65.8: 29.25
+	Hs
		948713 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR10A_HUMAN (32-159): 1.03e-12: 65.4: 27.16
+	Hs
		1214007 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KRA45_HUMAN (19-159): 7.59e-13: 64.7: 31.40
+	Hs
		1214006 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR411_HUMAN (1-131): 1.27e-12: 64.3: 34.59
+	Hs
		505331 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KRA23_HUMAN (19-159): 8.4e-12: 60.8: 25.53
+	Hs
		949708 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR101_HUMAN (41-149): 1.96e-10: 59.3: 30.91
+	Hs
		1214000 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR412_HUMAN (62-158): 1.9e-10: 58.5: 30.10
+	Hs
		950161 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR106_HUMAN (2-159): 5.16e-10: 58.5: 27.81
+	Hs
		950935 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR10B_HUMAN (2-136): 1.1e-09: 57.4: 24.84
+	Hs
		948277 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR121_HUMAN (38-131): 1.15e-09: 54.3: 29.79
+	Hs
		949556 LCE1E_HUMAN (1-118): 2.37e-50: 157: 100.00		KR123_HUMAN (26-121): 1.09e-09: 54.3: 26.80