HitPredict

Interactor 1: LCE1A (Q5T7P2)
Late cornified envelope protein 1A (Late envelope protein 1)
Gene: LCE1A

Interactor 2: KRA44 (Q9BYR3)
Keratin-associated protein 4-4 (Keratin-associated protein 4-13) (Keratin-associated protein 4.13) (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.4)
Gene: KRTAP4-4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 110 Hs			1 166
+	Hs
		1214277 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR412_HUMAN (1-166): 1.14e-30: 111: 63.18
+	Hs
		1214270 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KRA13_HUMAN (2-165): 1.33e-27: 102: 36.36
+	Hs
		948336 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR122_HUMAN (28-166): 1.44e-26: 99.4: 34.29
+	Hs
		950784 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR109_HUMAN (3-156): 1.5e-24: 97.9: 33.14
+	Hs
		1214282 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR411_HUMAN (4-131): 1.38e-24: 95.9: 43.14
+	Hs
		1214283 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KRA41_HUMAN (15-166): 1.42e-23: 92.1: 41.45
+	Hs
		950277 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR107_HUMAN (11-165): 6.45e-20: 86.7: 26.34
+	Hs
		1214284 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KRA45_HUMAN (3-166): 4.78e-19: 81.3: 46.95
+	Hs
		950515 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR108_HUMAN (19-165): 2.66e-18: 80.9: 28.81
+	Hs
		1214280 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KRA93_HUMAN (2-151): 2.18e-17: 76.3: 37.42
+	Hs
		949710 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR101_HUMAN (32-166): 6.53e-15: 72: 30.22
+	Hs
		950163 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR106_HUMAN (51-165): 2.82e-14: 70.9: 34.35
+	Hs
		1214279 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KRA98_HUMAN (2-126): 1.55e-13: 66.3: 35.20
+	Hs
		1214281 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KRA92_HUMAN (3-116): 3.49e-12: 62.8: 43.36
+	Hs
		1214269 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR111_HUMAN (10-164): 1.46e-11: 60.9: 27.10
+	Hs
		505333 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KRA23_HUMAN (49-166): 5.04e-11: 59: 38.98
+	Hs
		1059653 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KRA11_HUMAN (2-106): 2.24e-10: 58.2: 30.19
+	Hs
		948279 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR121_HUMAN (51-137): 6.08e-10: 55.1: 31.03
+	Hs
		949558 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR123_HUMAN (34-126): 2.54e-09: 53.6: 31.18
+	Hs
		949655 LCE1A_HUMAN (1-110): 7.6e-45: 142: 100.00		KR124_HUMAN (23-136): 4.11e-09: 53.2: 36.52