HitPredict

Interactor 1: TR10A (O00220)
Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261)
Gene: TNFRSF10A

Interactor 2: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 468 Hs			1 193
+	Hs
		121467 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		121470 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		121472 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		121466 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		121436 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		121469 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		121464 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54
+	Hs
		154335 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		154338 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		154295 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00
+	Hs
		154343 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		154333 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		154300 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		154336 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		154332 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54
+	Hs
		584359 TNR1A_HUMAN (100-448): 7e-64: 215: 18.21		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		584368 TNR1A_HUMAN (100-448): 7e-64: 215: 18.21		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		436154 TNR1A_HUMAN (100-448): 7e-64: 215: 18.21		RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00
+	Hs
		738655 TNR3_HUMAN (73-411): 2.64e-58: 200: 18.26		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		738654 TNR3_HUMAN (73-411): 2.64e-58: 200: 18.26		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30