Protein: GLP1R
Glucagon-like peptide 1 receptor (GLP-1 receptor) (GLP-1-R) (GLP-1R)

Gene: GLP1R
Organism: Homo sapiens
Interactions: 120
UniProt ID: P43220

Gene Ontology (top 5):
GO:0004888 - transmembrane signaling receptor activity
GO:0004967 - glucagon receptor activity
GO:0005886 - plasma membrane
GO:0007166 - cell surface receptor signaling pathway
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

351818

GLUC
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide

2

1

Small-scale

0.738

High

793723

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

9

Small-scale

0.621

High

793715

CD81
CD81 antigen

2

14

Small-scale

0.619

High

793726

IFM3
Interferon-induced transmembrane protein 3

2

1

Small-scale

0.619

High

793747

S15A4
Solute carrier family 15 member 4

2

1

Small-scale

0.619

High

793740

NT2NA
Notch homolog 2 N-terminal-like protein A

2

3

High-throughput

0.578

High

793710

RAB5C
Ras-related protein Rab-5C

1

1

Small-scale

0.561

High

793721

RAB5B
Ras-related protein Rab-5B

1

1

Small-scale

0.561

High

793727

CAV1
Caveolin-1

1

2

Small-scale

0.561

High

642019

KRA59
Keratin-associated protein 5-9

2

8

High-throughput

0.553

High

793728

KRA11
Keratin-associated protein 1-1

2

7

High-throughput

0.553

High

793742

KRA13
Keratin-associated protein 1-3

2

5

High-throughput

0.553

High

176009

GPR37
Prosaposin receptor GPR37

1

6

Small-scale

0.552

High

213259

SNG3
Synaptogyrin-3

1

6

Small-scale

0.552

High

274955

RENR
Renin receptor

1

1

Small-scale

0.552

High

397709

CFAI
Complement factor I

1

6

Small-scale

0.552

High

409503

HEPS
Serine protease hepsin

1

5

Small-scale

0.552

High

740893

FDFT
Squalene synthase

1

2

Small-scale

0.552

High

793711

APLP1
Amyloid beta precursor like protein 1

1

3

Small-scale

0.552

High

793720

MYL6
Myosin light polypeptide 6

1

9

Small-scale

0.552

High

793736

PIGG
GPI ethanolamine phosphate transferase 2

1

9

Small-scale

0.552

High

793737

MFSD5
Molybdate-anion transporter

1

2

Small-scale

0.552

High

793758

ELOV1
Very long chain fatty acid elongase 1

1

6

Small-scale

0.552

High

793763

AT131
Endoplasmic reticulum transmembrane helix translocase

1

10

Small-scale

0.552

High

793773

STML2
Stomatin-like protein 2, mitochondrial

1

1

Small-scale

0.552

High

123528

PGRC1
Membrane-associated progesterone receptor component 1

1

0

Small-scale

0.537

High

179309

COPT2
Protein SLC31A2

1

0

Small-scale

0.529

High

277383

GABR2
Gamma-aminobutyric acid type B receptor subunit 2

1

0

Small-scale

0.529

High

325998

TSN13
Tetraspanin-13

1

0

Small-scale

0.529

High

670587

ERP29
Endoplasmic reticulum resident protein 29

1

0

Small-scale

0.529

High

793738

PAQR6
Membrane progestin receptor delta

1

0

Small-scale

0.529

High

793743

CEND
Cell cycle exit and neuronal differentiation protein 1

1

0

Small-scale

0.529

High

793753

APH1A
Gamma-secretase subunit APH-1A

1

0

Small-scale

0.529

High

793754

AP2M1
AP-2 complex subunit mu

1

0

Small-scale

0.529

High

793755

VATO
V-type proton ATPase 21 kDa proteolipid subunit c''

1

0

Small-scale

0.529

High

793757

TM147
BOS complex subunit TMEM147

1

0

Small-scale

0.529

High

793761

CYTM1
Cysteine-rich and transmembrane domain-containing protein 1

1

0

Small-scale

0.529

High

793717

KR107
Keratin-associated protein 10-7

1

7

High-throughput

0.523

High

793718

KR108
Keratin-associated protein 10-8

1

7

High-throughput

0.523

High

793719

KR109
Keratin-associated protein 10-9

1

7

High-throughput

0.523

High

636839

ATPA
ATP synthase subunit alpha, mitochondrial

1

4

High-throughput

0.515

High

256735

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

3

Small-scale

0.504

High

793734

ACSF3
Malonate--CoA ligase ACSF3, mitochondrial

1

1

Small-scale

0.504

High

793746

SVOP
Synaptic vesicle 2-related protein

1

2

Small-scale

0.504

High

793770

STMN3
Stathmin-3

1

1

Small-scale

0.504

High

215808

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

1

Small-scale

0.481

High

306992

RTN3
Reticulon-3

1

1

Small-scale

0.481

High

310540

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

Small-scale

0.481

High

426817

ASGR2
Asialoglycoprotein receptor 2

1

4

Small-scale

0.481

High

446016

CD63
CD63 antigen

1

14

Small-scale

0.481

High

562897

STMN1
Stathmin

1

1

Small-scale

0.481

High

793713

BI1
Bax inhibitor 1

1

4

Small-scale

0.481

High

793714

GP2
Pancreatic secretory granule membrane major glycoprotein GP2

1

1

Small-scale

0.481

High

793722

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

1

Small-scale

0.481

High

793730

ARFRP
ADP-ribosylation factor-related protein 1

1

1

Small-scale

0.481

High

793741

LFG1
Protein lifeguard 1

1

4

Small-scale

0.481

High

793756

RNF5
E3 ubiquitin-protein ligase RNF5

1

1

Small-scale

0.481

High

793764

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

1

Small-scale

0.481

High

793765

GP108
Protein GPR108

1

4

Small-scale

0.481

High

793766

RTN4
Reticulon-4

1

1

Small-scale

0.481

High

793767

AIG1
Androgen-induced gene 1 protein

1

2

Small-scale

0.481

High

793776

DHRS7
Dehydrogenase/reductase SDR family member 7

1

4

Small-scale

0.481

High

793777

MTCH2
Mitochondrial carrier homolog 2

1

6

Small-scale

0.481

High

484073

CALM3
Calmodulin-3

1

8

Small-scale

0.479

High

793708

ARRB1
Beta-arrestin-1

1

2

Small-scale

0.479

High

484576

NT2NC
Notch homolog 2 N-terminal-like protein C

1

3

High-throughput

0.470

High

315112

CLD7
Claudin-7

1

0

Small-scale

0.460

High

364840

FRIL
Ferritin light chain

1

0

Small-scale

0.460

High

483474

SAA1
Serum amyloid A-1 protein

1

0

Small-scale

0.460

High

580170

AMD
Peptidyl-glycine alpha-amidating monooxygenase

1

0

Small-scale

0.460

High

602505

COMT
Catechol O-methyltransferase

1

0

Small-scale

0.460

High

614267

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

Small-scale

0.460

High

793704

IEX1
Radiation-inducible immediate-early gene IEX-1

1

0

Small-scale

0.460

High

793706

T4S4
Transmembrane 4 L6 family member 4

1

0

Small-scale

0.460

High

793712

EMP2
Epithelial membrane protein 2

1

0

Small-scale

0.460

High

793739

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

1

0

Small-scale

0.460

High

793772

CC167
Coiled-coil domain-containing protein 167

1

0

Small-scale

0.460

High

793778

SELK
Selenoprotein K

1

0

Small-scale

0.460

High

793724

SUMO1
Small ubiquitin-related modifier 1

1

0

Small-scale

0.458

High

238039

UD19
UDP-glucuronosyltransferase 1A9

1

1

Small-scale

0.439

High

315166

SNG4
Synaptogyrin-4

1

6

Small-scale

0.439

High

428718

TRY2
Trypsin-2

1

5

Small-scale

0.439

High

434818

CXB1
Gap junction beta-1 protein

1

2

Small-scale

0.439

High

445251

CEL3B
Chymotrypsin-like elastase family member 3B

1

6

Small-scale

0.439

High

793705

AT5G3
ATP synthase F(0) complex subunit C3, mitochondrial

1

2

Small-scale

0.439

High

793716

KR103
Keratin-associated protein 10-3

1

7

High-throughput

0.439

High

793732

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

2

Small-scale

0.439

High

793774

POMT2
Protein O-mannosyl-transferase 2

1

1

Small-scale

0.439

High

67003

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

793760

KR171
Keratin-associated protein 17-1

2

0

High-throughput

0.316

High

793748

CR032
UPF0729 protein C18orf32

1

0

Small-scale

0.288

High

793762

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

Small-scale

0.288

High

793768

RM22
Large ribosomal subunit protein uL22m

1

0

Small-scale

0.288

High

793769

P4HTM
Transmembrane prolyl 4-hydroxylase

1

0

Small-scale

0.288

High

793775

RTRAF
RNA transcription, translation and transport factor protein

1

0

Small-scale

0.288

High

793779

SERP1
Stress-associated endoplasmic reticulum protein 1

1

0

Small-scale

0.288

High

488

NBPFJ
Neuroblastoma breakpoint family member 19

1

0

High-throughput

0.251

Low

68617

ZNF99
Zinc finger protein 99

1

0

Small-scale

0.251

Low

269294

SG2A1
Mammaglobin-B

1

0

Small-scale

0.251

Low

342165

ATP6
ATP synthase subunit a

1

0

Small-scale

0.251

Low

344174

A1AT
Alpha-1-antitrypsin

1

0

Small-scale

0.251

Low

371144

NU4LM
NADH-ubiquinone oxidoreductase chain 4L

1

0

Small-scale

0.251

Low

376528

COL
Colipase

1

0

Small-scale

0.251

Low

473102

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

Small-scale

0.251

Low

599289

AGT1
Alanine--glyoxylate aminotransferase

1

0

Small-scale

0.251

Low

793707

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

0

Small-scale

0.251

Low

793709

KHK
Ketohexokinase

1

0

Small-scale

0.251

Low

793725

HEPC
Hepcidin

1

0

Small-scale

0.251

Low

793729

FGL1
Fibrinogen-like protein 1

1

0

Small-scale

0.251

Low

793731

LAP4A
Lysosomal-associated transmembrane protein 4A

1

0

Small-scale

0.251

Low

793733

T176B
Transmembrane protein 176B

1

0

Small-scale

0.251

Low

793735

OCAD2
OCIA domain-containing protein 2

1

0

Small-scale

0.251

Low

793744

SYS1
Protein SYS1 homolog

1

0

Small-scale

0.251

Low

793745

CLIP4
CAP-Gly domain-containing linker protein 4

1

0

Small-scale

0.251

Low

793749

CD003
Uncharacterized protein C4orf3

1

0

Small-scale

0.251

Low

793750

NEUG
Neurogranin

1

0

Small-scale

0.251

Low

793751

SPTSA
Serine palmitoyltransferase small subunit A

1

0

Small-scale

0.251

Low

793752

TOM6
Mitochondrial import receptor subunit TOM6 homolog

1

0

Small-scale

0.251

Low

793759

SC11C
Signal peptidase complex catalytic subunit SEC11C

1

0

Small-scale

0.251

Low

793771

CNIH4
Protein cornichon homolog 4

1

0

Small-scale

0.251

Low


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Last updated: 15 Jul 2024