HitPredict

Interactor 1: SYT6 (Q5T7P8)
Synaptotagmin-6 (Synaptotagmin VI) (SytVI)
Gene: SYT6

Interactor 2: MADD (Q8WXG6)
MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (Rab3GEP)
Gene: MADD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 510 Hs			1 1647
+	Hs
		1286631 SYT9_HUMAN (6-499): 4.51e-155: 452: 58.55		MADD_HUMAN (1-1647): 0: 2402: 100.00
+	Hs
		1360616 SYT3_HUMAN (1-510): 7.79e-137: 409: 43.46		MADD_HUMAN (1-1647): 0: 2402: 100.00
+	Hs
		1331827 SYT2_HUMAN (230-501): 1.7e-91: 287: 50.92		MADD_HUMAN (1-1647): 0: 2402: 100.00
+	Hs
		1308124 SYT12_HUMAN (122-497): 1.78e-77: 250: 28.42		MADD_HUMAN (1-1647): 0: 2402: 100.00