HitPredict

Interactor 1: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Interactor 2: YTHD3 (Q7Z739)
YTH domain-containing family protein 3 (DF3)
Gene: YTHDF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0010494 - cytoplasmic stress granule GO:0043488 - regulation of mRNA stability
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1133 Hs			1 585
+	Hs
		1215922 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTHD2_HUMAN (1-581): 1.37e-158: 467: 65.81
+	Hs
		1215810 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTHD1_HUMAN (1-570): 2.96e-139: 417: 67.31
+	Hs
		1215830 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTDC2_HUMAN (286-551): 7.53e-57: 208: 21.61
+	Hs
		1215776 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTDC1_HUMAN (327-581): 8.19e-55: 199: 18.38
+	Hs
		1280744 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD3_HUMAN (1-568): 8.5e-174: 506: 100.00
+	Hs
		1438109 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD2_HUMAN (1-581): 1.37e-158: 467: 65.81
+	Hs
		1418734 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD1_HUMAN (1-570): 2.96e-139: 417: 67.31
+	Hs
		1435110 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTDC2_HUMAN (286-551): 7.53e-57: 208: 21.61
+	Hs
		1398443 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTDC1_HUMAN (327-581): 8.19e-55: 199: 18.38