Protein: PKHO1
Pleckstrin homology domain-containing family O member 1 (PH domain-containing family O member 1) (C-Jun-binding protein) (JBP) (Casein kinase 2-interacting protein 1) (CK2-interacting protein 1) (CKIP-1) (Osteoclast maturation-associated gene 120 protein)

Gene: PKHO1, PLEKHO1
Organism: Homo sapiens
Interactions: 82
UniProt ID: Q53GL0

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007520 - myoblast fusion
GO:0008360 - regulation of cell shape
GO:0032587 - ruffle membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1120872

PKHO1
Pleckstrin homology domain-containing family O member 1

2

1

Small-scale

0.800

High

235082

DOK2
Docking protein 2

2

0

High-throughput

0.770

High

681883

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

Small-scale

0.756

High

682182

AKT2
RAC-beta serine/threonine-protein kinase

1

2

Small-scale

0.747

High

934216

CSK21
Casein kinase II subunit alpha

1

1

Small-scale

0.740

High

1120900

SMUF1
E3 ubiquitin-protein ligase SMURF1

6

0

Small-scale

0.708

High

1120903

NLE1
Notchless protein homolog 1

2

0

High-throughput

0.679

High

1120907

AKT3
RAC-gamma serine/threonine-protein kinase

1

2

Small-scale

0.665

High

1052883

FLNC
Filamin-C

2

1

High-throughput

0.628

High

1057943

RRP5
Protein RRP5 homolog

2

1

High-throughput

0.628

High

349373

RASH
GTPase HRas

1

3

High-throughput

0.618

High

350218

RASK
GTPase KRas

1

3

High-throughput

0.618

High

813052

CAZA2
F-actin-capping protein subunit alpha-2

3

3

High-throughput

0.609

High

813518

CAPZB
F-actin-capping protein subunit beta

3

1

High-throughput

0.609

High

48114

UBA6
Ubiquitin-like modifier-activating enzyme 6

2

0

High-throughput

0.602

High

177505

NVL
Nuclear valosin-containing protein-like

2

0

High-throughput

0.602

High

843710

FXR1
RNA-binding protein FXR1

2

0

High-throughput

0.602

High

1120877

TRM1L
TRMT1-like protein

2

0

High-throughput

0.602

High

1120879

CENPV
Centromere protein V

2

0

High-throughput

0.602

High

1120884

DDX51
ATP-dependent RNA helicase DDX51

2

0

High-throughput

0.602

High

1120897

DDX31
ATP-dependent DNA helicase DDX31

2

0

High-throughput

0.602

High

1120899

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

2

0

High-throughput

0.602

High

1120908

NOC2L
Nucleolar complex protein 2 homolog

2

0

High-throughput

0.602

High

1120888

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

0

High-throughput

0.598

High

305478

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.580

High

941725

CP4F2
Cytochrome P450 4F2

2

0

High-throughput

0.580

High

1021976

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

2

0

High-throughput

0.580

High

1120889

CEP19
Centrosomal protein of 19 kDa

2

0

High-throughput

0.580

High

907052

PRS8
26S proteasome regulatory subunit 8

1

0

Small-scale

0.576

High

857141

CAZA1
F-actin-capping protein subunit alpha-1

2

3

High-throughput

0.574

High

1120873

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

2

1

High-throughput

0.574

High

1120875

SPT2
Protein SPT2 homolog

2

1

High-throughput

0.574

High

1120909

TRAF6
TNF receptor-associated factor 6

1

1

Small-scale

0.561

High

348704

RASN
GTPase NRas

1

3

High-throughput

0.553

High

1120891

SMAD5
Mothers against decapentaplegic homolog 5

1

0

Small-scale

0.537

High

123964

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.513

High

322716

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.513

High

760102

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

806039

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

1120887

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.513

High

1120892

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.513

High

1120901

SSF1
Suppressor of SWI4 1 homolog

1

0

High-throughput

0.513

High

261274

FLNB
Filamin-B

1

1

High-throughput

0.508

High

945805

IN35
Interferon-induced 35 kDa protein

1

2

High-throughput

0.508

High

636348

DNJB1
DnaJ homolog subfamily B member 1

1

0

High-throughput

0.486

High

893049

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.486

High

1120898

PAAT
ATPase PAAT

1

0

High-throughput

0.486

High

174944

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

997347

Q08AM2
ADAM33 protein

1

1

High-throughput

0.470

High

1118823

Q4VAQ0
COL8A2 protein

1

1

High-throughput

0.470

High

626316

CO8A2
Collagen alpha-2(VIII) chain

1

1

High-throughput

0.439

High

1120894

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

1

High-throughput

0.439

High

1047115

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

1120882

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

59597

GTPBA
GTP-binding protein 10

2

0

High-throughput

0.328

High

230054

NPA1P
Nucleolar pre-ribosomal-associated protein 1

2

0

High-throughput

0.328

High

297865

SC24D
Protein transport protein Sec24D

2

0

High-throughput

0.328

High

1120881

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

2

0

High-throughput

0.328

High

1120893

GTPB2
GTP-binding protein 2

2

0

High-throughput

0.328

High

1120905

RL26L
Ribosomal protein uL24-like

2

0

High-throughput

0.318

High

58292

TM218
Transmembrane protein 218

2

0

High-throughput

0.316

High

352634

TNFA
Tumor necrosis factor

2

0

High-throughput

0.316

High

1074882

PAQRB
Monocyte to macrophage differentiation factor

2

0

High-throughput

0.316

High

1079335

VAMP3
Vesicle-associated membrane protein 3

2

0

High-throughput

0.316

High

1120874

TSPO2
Translocator protein 2

2

0

High-throughput

0.316

High

1120876

BRID5
BRICHOS domain-containing protein 5

2

0

High-throughput

0.316

High

1120878

LRP10
Low-density lipoprotein receptor-related protein 10

2

0

High-throughput

0.316

High

1120880

TSN33
Tetraspanin-33

2

0

High-throughput

0.316

High

1120883

TR1L1
Translocating chain-associated membrane protein 1-like 1

2

0

High-throughput

0.316

High

1120886

CD003
Uncharacterized protein C4orf3

2

0

High-throughput

0.316

High

1120896

SNAB
Beta-soluble NSF attachment protein

2

0

High-throughput

0.316

High

1120906

T3JAM
TRAF3-interacting JNK-activating modulator

2

0

High-throughput

0.316

High

1115529

GLYR1
Cytokine-like nuclear factor N-PAC

1

0

High-throughput

0.279

Low

1120885

NOC3L
Nucleolar complex protein 3 homolog

1

0

High-throughput

0.279

Low

1120890

ODAD1
Outer dynein arm-docking complex subunit 1

1

0

High-throughput

0.279

Low

1120902

SDA1
Protein SDA1 homolog

1

0

High-throughput

0.279

Low

1120904

RBM28
RNA-binding protein 28

1

0

High-throughput

0.279

Low

1067724

PDIA6
Protein disulfide-isomerase A6

1

0

High-throughput

0.269

Low

1120895

THS7B
Thrombospondin type-1 domain-containing protein 7B

1

0

High-throughput

0.268

Low

240026

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

484829

AMY1B
Alpha-amylase 1B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024