HitPredict

Interactor 1: MFN1 (Q8IWA4)
Mitofusin-1 (EC 3.6.5.-) (Fzo homolog) (Transmembrane GTPase MFN1)
Gene: MFN1

Interactor 2: MARH5 (Q9NX47)
E3 ubiquitin-protein ligase MARCHF5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (Mitochondrial ubiquitin ligase) (MITOL) (RING finger protein 153) (RING-type E3 ubiquitin transferase MARCHF5)
Gene: MARCHF5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	34964862, 20103533, 23253261, 24722297
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0016020 - membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 741 Hs			1 278
+	Mm
		1108414 MFN1_MOUSE (1-741): 0: 1198: 90.55		MARH5_MOUSE (1-278): 1.37e-162: 454: 100.00
+	Mm
		1108413 MFN2_MOUSE (1-737): 0: 1112: 64.55		MARH5_MOUSE (1-278): 1.37e-162: 454: 100.00
+	Hs
		304886 MFN2_HUMAN (1-737): 0: 1096: 63.46		MARH5_HUMAN (1-278): 1.37e-162: 454: 100.00