Protein: DNAJ
Chaperone protein DnaJ (HSP40) (Heat shock protein J)

Gene: DNAJ
Organism: Escherichia coli K-12
Interactions: 115
UniProt ID: P08622

Gene Ontology (top 5):
GO:0003756 - protein disulfide isomerase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006260 - DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

473242

DNAK
Chaperone protein DnaK

4

20

Small-scale

0.886

High

473317

USPG
Universal stress protein UP12

3

0

High-throughput

0.638

High

449999

MALT
HTH-type transcriptional regulator MalT

2

0

High-throughput

0.613

High

473302

GLMS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

2

4

High-throughput

0.611

High

473255

RUVB
Holliday junction branch migration complex subunit RuvB

2

7

High-throughput

0.601

High

473244

KPRS
Ribose-phosphate pyrophosphokinase

2

5

High-throughput

0.594

High

473289

THIO2
Thioredoxin 2

1

0

High-throughput

0.593

High

473333

LYSAC
Peptidyl-lysine N-acetyltransferase PatZ

2

0

High-throughput

0.592

High

473243

IF2
Translation initiation factor IF-2

2

9

High-throughput

0.588

High

473250

RS10
Small ribosomal subunit protein uS10

2

3

High-throughput

0.588

High

473267

CSPC
Cold shock-like protein CspC

2

1

High-throughput

0.588

High

473270

ATPB
ATP synthase subunit beta

2

5

High-throughput

0.588

High

473272

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

2

9

High-throughput

0.588

High

473279

GYRA
DNA gyrase subunit A

2

1

High-throughput

0.588

High

473286

RHO
Transcription termination factor Rho

2

5

High-throughput

0.588

High

473287

RS14
Small ribosomal subunit protein uS14

2

1

High-throughput

0.588

High

473293

GATY
D-tagatose-1,6-bisphosphate aldolase subunit GatY

2

1

High-throughput

0.588

High

473319

RL24
Large ribosomal subunit protein uL24

2

1

High-throughput

0.588

High

368942

SYGA
Glycine--tRNA ligase alpha subunit

2

0

High-throughput

0.585

High

382535

RS6
Small ribosomal subunit protein bS6

2

0

High-throughput

0.585

High

473296

RNPH
Truncated inactive ribonuclease PH

2

0

High-throughput

0.585

High

473280

NUSG
Transcription termination/antitermination protein NusG

2

0

High-throughput

0.576

High

473294

EFTU1
Elongation factor Tu 1

2

7

High-throughput

0.571

High

473338

YAJL
Protein/nucleic acid deglycase 3

2

1

Small-scale

0.571

High

473276

RL23
Large ribosomal subunit protein uL23

2

0

High-throughput

0.563

High

473291

IBPA
Small heat shock protein IbpA

2

0

High-throughput

0.563

High

473238

HSLU
ATP-dependent protease ATPase subunit HslU

1

1

High-throughput

0.561

High

473299

SELB
Selenocysteine-specific elongation factor

1

10

High-throughput

0.561

High

473303

SRMB
ATP-dependent RNA helicase SrmB

1

5

High-throughput

0.561

High

395059

DNAA
Chromosomal replication initiator protein DnaA

1

0

High-throughput

0.537

High

473235

NARG
Respiratory nitrate reductase 1 alpha chain

1

0

High-throughput

0.537

High

473316

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.537

High

368798

SYI
Isoleucine--tRNA ligase

1

4

High-throughput

0.536

High

420135

KDSB
3-deoxy-manno-octulosonate cytidylyltransferase

1

1

High-throughput

0.536

High

431303

PDXB
Erythronate-4-phosphate dehydrogenase

1

2

High-throughput

0.536

High

473240

MNMG
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

1

2

High-throughput

0.536

High

473252

RS2
Small ribosomal subunit protein uS2

1

4

High-throughput

0.536

High

473254

RS5
Small ribosomal subunit protein uS5

1

5

High-throughput

0.536

High

473281

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex

1

2

High-throughput

0.536

High

473301

PUR4
Phosphoribosylformylglycinamidine synthase

1

1

High-throughput

0.536

High

473304

LPXD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

1

4

High-throughput

0.536

High

473307

MUKB
Chromosome partition protein MukB

1

4

High-throughput

0.536

High

473311

UBIH
2-octaprenyl-6-methoxyphenol hydroxylase

1

1

High-throughput

0.536

High

473337

PRPE
Propionate--CoA ligase

1

1

High-throughput

0.536

High

420199

RECD
RecBCD enzyme subunit RecD

1

0

High-throughput

0.513

High

473234

PT1
Phosphoenolpyruvate-protein phosphotransferase

1

0

High-throughput

0.513

High

473237

ARGR
Arginine repressor

1

0

High-throughput

0.513

High

473259

YEEN
Probable transcriptional regulatory protein YeeN

1

0

High-throughput

0.513

High

473261

CHEW
Chemotaxis protein CheW

1

0

High-throughput

0.513

High

473278

FKBX
FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.513

High

473282

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.513

High

473284

RFAH
Transcription antitermination protein RfaH

1

0

High-throughput

0.513

High

473290

TLDD
Metalloprotease TldD

1

0

High-throughput

0.513

High

473297

LPXB
Lipid-A-disaccharide synthase

1

0

High-throughput

0.513

High

473298

GLPD
Aerobic glycerol-3-phosphate dehydrogenase

1

0

High-throughput

0.513

High

473306

ADD
Adenosine deaminase

1

0

High-throughput

0.513

High

473308

YICC
Endoribonuclease YicC

1

0

High-throughput

0.513

High

473326

HYFR
DNA-binding transcriptional activator HyfR

1

0

High-throughput

0.513

High

473288

RPOH
RNA polymerase sigma factor RpoH

1

1

Small-scale

0.501

High

473258

SUCC
Succinate--CoA ligase [ADP-forming] subunit beta

1

3

High-throughput

0.500

High

473295

EFTU2
Elongation factor Tu 2

1

7

High-throughput

0.500

High

473246

RECA
Protein RecA

1

7

High-throughput

0.484

High

473248

RL19
Large ribosomal subunit protein bL19

1

1

High-throughput

0.484

High

473249

RL1
Large ribosomal subunit protein uL1

1

2

High-throughput

0.484

High

473251

RS13
Small ribosomal subunit protein uS13

1

5

High-throughput

0.484

High

473256

METK
S-adenosylmethionine synthase

1

4

High-throughput

0.484

High

473260

RPOC
DNA-directed RNA polymerase subunit beta'

1

2

High-throughput

0.484

High

473264

DEAD
ATP-dependent RNA helicase DeaD

1

3

High-throughput

0.484

High

473266

MREB
Cell shape-determining protein MreB

1

20

High-throughput

0.484

High

473268

PSTB
Phosphate import ATP-binding protein PstB

1

2

High-throughput

0.484

High

473271

FTSA
Cell division protein FtsA

1

20

High-throughput

0.484

High

473320

RL22
Large ribosomal subunit protein uL22

1

3

High-throughput

0.484

High

473312

YBIB
Uncharacterized protein YbiB

1

0

High-throughput

0.479

High

473236

GRPE
Protein GrpE

1

5

Small-scale

0.479

High

473239

EFG
Elongation factor G

1

7

High-throughput

0.479

High

473253

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.479

High

473241

HFQ
RNA-binding protein Hfq

1

0

High-throughput

0.464

High

473245

PYRH
Uridylate kinase

1

0

High-throughput

0.464

High

473247

RL10
Large ribosomal subunit protein uL10

1

0

High-throughput

0.464

High

473262

ALF1
Fructose-bisphosphate aldolase class 1

1

0

High-throughput

0.464

High

473263

PTA
Phosphate acetyltransferase

1

0

High-throughput

0.464

High

473265

ULAR
HTH-type transcriptional regulator UlaR

1

0

High-throughput

0.464

High

473269

YBCJ
Putative RNA-binding protein YbcJ

1

0

High-throughput

0.464

High

473277

MIAB
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase

1

0

High-throughput

0.464

High

473323

YJBJ
UPF0337 protein YjbJ

1

0

High-throughput

0.464

High

473274

EXBB
Biopolymer transport protein ExbB

1

0

High-throughput

0.458

High

473275

YGAM
Uncharacterized protein YgaM

1

0

High-throughput

0.458

High

473283

GCH1L
GTP cyclohydrolase 1 type 2 homolog

1

0

High-throughput

0.458

High

473300

DNLJ
DNA ligase

1

0

High-throughput

0.458

High

473310

HYPD
Hydrogenase maturation factor HypD

1

0

High-throughput

0.458

High

473315

FDHD
Sulfur carrier protein FdhD

1

0

High-throughput

0.458

High

473324

MBHS
Hydrogenase-1 small chain

1

0

High-throughput

0.458

High

473325

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

473329

PXPA
5-oxoprolinase subunit A

1

0

High-throughput

0.458

High

473321

CLPB
Chaperone protein ClpB

1

7

Small-scale

0.445

High

473318

YJJU
Uncharacterized protein YjjU

1

1

High-throughput

0.437

High

473330

YBJX
Uncharacterized protein YbjX

2

0

High-throughput

0.318

High

473285

SOHB
Probable protease SohB

2

0

High-throughput

0.305

High

444240

BTUE
Thioredoxin/glutathione peroxidase BtuE

1

0

High-throughput

0.279

Low

473257

SMG
Protein Smg

1

0

High-throughput

0.279

Low

473273

CYOA
Cytochrome bo(3) ubiquinol oxidase subunit 2

1

0

High-throughput

0.279

Low

473305

RECJ
Single-stranded-DNA-specific exonuclease RecJ

1

0

High-throughput

0.279

Low

473309

DIND
DNA damage-inducible protein D

1

0

High-throughput

0.279

Low

473314

LPTD
LPS-assembly protein LptD

1

0

High-throughput

0.279

Low

473327

YAGM
Uncharacterized protein YagM

1

0

High-throughput

0.279

Low

473331

YCGZ
Probable two-component-system connector protein YcgZ

1

0

High-throughput

0.279

Low

473332

NIMR
HTH-type transcriptional regulator NimR

1

0

High-throughput

0.279

Low

473334

YPJB
Protein YpjB

1

0

High-throughput

0.279

Low

473336

EUTJ
Ethanolamine utilization protein EutJ

1

0

High-throughput

0.279

Low

473322

YODC
Uncharacterized protein YodC

1

0

High-throughput

0.261

Low

473292

RELE
mRNA interferase toxin RelE

1

0

High-throughput

0.253

Low

450030

OMPC
Outer membrane porin C

1

0

High-throughput

0.249

Low

473313

YAFC
Uncharacterized HTH-type transcriptional regulator YafC

1

0

High-throughput

0.249

Low

473328

YBFL
Putative protein YbfL

1

0

High-throughput

0.232

Low

473335

YFCU
Putative outer membrane usher protein YfcU

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025