HitPredict

Interactor 1: PSD11 (O00231)
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5)
Gene: PSMD11

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.751

Property	Details
Experiments	35271311, 26186194, 28514442, 33961781, 34761751, 19615732, 18922472, 19490896
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 422 Hs			1 329
+	Hs
		1062909 PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		122113 PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Sp
		1350850 RPN6_SCHPO (13-419): 1.56e-91: 284: 54.90		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Sp
		1013801 RPN7_SCHPO (55-420): 1.19e-53: 185: 12.96		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Hs
		121825 PSD11_HUMAN (1-422): 1.54e-117: 351: 100.00		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		897284 CSN2_HUMAN (8-419): 1.5e-88: 277: 22.80		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		1062852 PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		1267131 CSN4_HUMAN (4-422): 5.53e-72: 233: 14.62		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		122058 PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29