HitPredict

Interactor 1: TRI59 (Q8IWR1)
Tripartite motif-containing protein 59 (EC 2.3.2.27) (RING finger protein 104) (Tumor suppressor TSBF-1)
Gene: TRIM59

Interactor 2: Q96FI0 (Q96FI0)
N-terminal E2 ubiquitin-conjugating enzyme (EC 2.3.2.23) (EC 2.3.2.25)
Gene: UBE2W

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 403 Hs			1 159
+	Hs
		1219285 TRI59_HUMAN (1-403): 1.38e-115: 344: 100.00		UBE2W_HUMAN (1-149): 1.75e-60: 185: 96.64
+	Hs
		584907 RO52_HUMAN (1-352): 8.74e-78: 249: 16.15		UB2D1_HUMAN (4-150): 1.86e-67: 203: 32.89
+	Hs
		584923 RO52_HUMAN (1-352): 8.74e-78: 249: 16.15		UB2D2_HUMAN (4-150): 6.91e-67: 201: 30.87
+	Hs
		584916 RO52_HUMAN (1-352): 8.74e-78: 249: 16.15		UB2D3_HUMAN (4-150): 1.2e-65: 198: 30.87
+	Hs
		584910 RO52_HUMAN (1-352): 8.74e-78: 249: 16.15		UB2E1_HUMAN (1-150): 1.27e-62: 192: 31.58
+	Hs
		895815 TRI68_HUMAN (1-350): 4.2e-74: 240: 15.24		UB2D3_HUMAN (4-150): 1.2e-65: 198: 30.87
+	Hs
		849366 TRI22_HUMAN (3-337): 9.41e-72: 234: 18.58		UB2D1_HUMAN (4-150): 1.86e-67: 203: 32.89
+	Hs
		849406 TRI11_HUMAN (3-354): 8.45e-72: 234: 19.55		UB2D1_HUMAN (4-150): 1.86e-67: 203: 32.89
+	Hs
		135922 RO52_HUMAN (1-352): 8.74e-78: 249: 16.15		UBE2C_HUMAN (3-156): 1.67e-60: 186: 32.47
+	Hs
		919822 TRI11_HUMAN (3-354): 8.45e-72: 234: 19.55		UB2D2_HUMAN (4-150): 6.91e-67: 201: 30.87
+	Hs
		585028 RO52_HUMAN (1-352): 8.74e-78: 249: 16.15		UBE2W_HUMAN (1-149): 1.75e-60: 185: 96.64
+	Hs
		849453 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2D1_HUMAN (4-150): 1.86e-67: 203: 32.89
+	Hs
		895876 TRI11_HUMAN (3-354): 8.45e-72: 234: 19.55		UB2D3_HUMAN (4-150): 1.2e-65: 198: 30.87
+	Hs
		919870 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2D2_HUMAN (4-150): 6.91e-67: 201: 30.87
+	Hs
		895921 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2D3_HUMAN (4-150): 1.2e-65: 198: 30.87
+	Hs
		1297370 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2E2_HUMAN (1-150): 1.82e-64: 197: 32.24
+	Hs
		851867 TRI11_HUMAN (3-354): 8.45e-72: 234: 19.55		UB2E1_HUMAN (1-150): 1.27e-62: 192: 31.58
+	Hs
		1282350 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2E3_HUMAN (1-150): 5.16e-64: 196: 32.90
+	Hs
		851889 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2E1_HUMAN (1-150): 1.27e-62: 192: 31.58
+	Hs
		1284888 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UBE2W_HUMAN (1-149): 1.75e-60: 185: 96.64