HitPredict

Interactor 1: KLD8B (Q8IXV7)
Kelch domain-containing protein 8B
Gene: KLHDC8B

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 354 Hs			1 543
+	Hs
		1222996 KLD8A_HUMAN (1-352): 5.55e-97: 293: 45.74		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		1306718 KLHL8_HUMAN (67-353): 3.05e-70: 232: 21.88		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		826757 KLD8A_HUMAN (1-352): 5.55e-97: 293: 45.74		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821303 KLD8A_HUMAN (1-352): 5.55e-97: 293: 45.74		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573358 KLD8A_HUMAN (1-352): 5.55e-97: 293: 45.74		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		826964 NS1BP_HUMAN (1-260): 2.76e-78: 254: 24.52		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826926 KLHL8_HUMAN (67-353): 3.05e-70: 232: 21.88		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821446 KLHL8_HUMAN (67-353): 3.05e-70: 232: 21.88		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573513 KLHL8_HUMAN (67-353): 3.05e-70: 232: 21.88		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		826755 KLD8B_HUMAN (1-229): 1.79e-46: 163: 23.65		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821299 KLD8B_HUMAN (1-229): 1.79e-46: 163: 23.65		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		843278 KLD8A_HUMAN (1-352): 5.55e-97: 293: 45.74		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79