Protein: RYR1
Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor)

Gene: RYR1
Organism: Homo sapiens
Interactions: 40
UniProt ID: P21817

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0003151 - outflow tract morphogenesis
GO:0005219 - ryanodine-sensitive calcium-release channel activity
GO:0005245 - voltage-gated calcium channel activity
GO:0005262 - calcium channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

641328

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

4

10

Small-scale

0.893

High

641344

RYR2
Ryanodine receptor 2

2

17

Small-scale

0.799

High

641342

TITIN
Titin

1

15

High-throughput

0.698

High

641335

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

12

High-throughput

0.691

High

641334

TRDN
Triadin

4

8

Small-scale

0.688

High

641320

RYR1
Ryanodine receptor 1

1

16

Small-scale

0.647

High

641341

HOME1
Homer protein homolog 1

2

8

Small-scale

0.629

High

641338

RN123
E3 ubiquitin-protein ligase RNF123

1

15

High-throughput

0.618

High

641345

HOME2
Homer protein homolog 2

1

8

Small-scale

0.561

High

641346

HOME3
Homer protein homolog 3

1

5

Small-scale

0.561

High

279281

TULP3
Tubby-related protein 3

1

1

High-throughput

0.541

High

641324

MYOM2
Myomesin-2

1

11

High-throughput

0.541

High

641337

PDLI3
PDZ and LIM domain protein 3

1

5

High-throughput

0.541

High

592922

ANK1
Ankyrin-1

1

4

Small-scale

0.501

High

641321

S10A1
Protein S100-A1

1

5

Small-scale

0.501

High

641323

TERF1
Telomeric repeat-binding factor 1

1

2

High-throughput

0.501

High

641325

CAV3
Caveolin-3

1

3

Small-scale

0.501

High

641333

AKAP6
A-kinase anchor protein 6

1

12

Small-scale

0.501

High

641340

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

2

High-throughput

0.489

High

403821

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

408670

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.479

High

587557

DESP
Desmoplakin

1

20

High-throughput

0.479

High

593906

NCK1
SH2/SH3 adapter protein NCK1

1

5

High-throughput

0.479

High

618974

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

4

High-throughput

0.479

High

641322

SOX2
Transcription factor SOX-2

1

10

High-throughput

0.479

High

641326

RAB14
Ras-related protein Rab-14

1

3

High-throughput

0.479

High

641329

GRB2
Growth factor receptor-bound protein 2

1

6

High-throughput

0.479

High

641347

UBQL2
Ubiquilin-2

1

6

High-throughput

0.479

High

641336

MIDN
Midnolin

1

0

High-throughput

0.458

High

390862

TRFE
Serotransferrin

1

1

High-throughput

0.445

High

641327

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

7

Small-scale

0.445

High

641330

RACK1
Small ribosomal subunit protein RACK1

1

8

High-throughput

0.445

High

641331

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

5

Small-scale

0.445

High

641332

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

5

Small-scale

0.445

High

641348

S27A6
Long-chain fatty acid transport protein 6

1

3

High-throughput

0.445

High

352961

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

641343

ESR2
Estrogen receptor beta

1

20

High-throughput

0.437

High

641339

A16L1
Autophagy-related protein 16-1

1

16

High-throughput

0.407

High

641349

RT23
Small ribosomal subunit protein mS23

1

1

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025