HitPredict

Interactor 1: RN103 (O00237)
E3 ubiquitin-protein ligase RNF103 (EC 2.3.2.27) (KF-1) (hKF-1) (RING finger protein 103) (RING-type E3 ubiquitin transferase RNF103) (Zinc finger protein 103 homolog) (Zfp-103)
Gene: RNF103

Interactor 2: UB2E2 (Q96LR5)
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)
Gene: UBE2E2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25224329, 18615712
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 201
+	Hs
		122275 RN103_HUMAN (1-685): 0: 1271: 100.00		UB2D4_HUMAN (55-200): 9.37e-83: 243: 63.01
+	Hs
		122263 RN103_HUMAN (1-685): 0: 1271: 100.00		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		122256 RN103_HUMAN (1-685): 0: 1271: 100.00		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		122257 RN103_HUMAN (1-685): 0: 1271: 100.00		UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71
+	Hs
		122259 RN103_HUMAN (1-685): 0: 1271: 100.00		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		122260 RN103_HUMAN (1-685): 0: 1271: 100.00		UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27
+	Hs
		196372 PJA2_HUMAN (526-685): 7.54e-34: 140: 21.71		UB2D4_HUMAN (55-200): 9.37e-83: 243: 63.01
+	Hs
		1245284 PJA1_HUMAN (522-669): 3.07e-31: 131: 22.50		UB2E3_HUMAN (1-201): 6.37e-85: 251: 79.71
+	Hs
		196294 PJA2_HUMAN (526-685): 7.54e-34: 140: 21.71		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		196282 PJA2_HUMAN (526-685): 7.54e-34: 140: 21.71		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		196289 PJA2_HUMAN (526-685): 7.54e-34: 140: 21.71		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		919792 PJA1_HUMAN (522-669): 3.07e-31: 131: 22.50		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		1205108 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UB2E3_HUMAN (1-201): 6.37e-85: 251: 79.71
+	Hs
		895852 PJA1_HUMAN (522-669): 3.07e-31: 131: 22.50		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		919775 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		849362 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		851839 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71
+	Hs
		895840 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		196290 PJA2_HUMAN (526-685): 7.54e-34: 140: 21.71		UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27
+	Hs
		896485 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27