Protein: AAKG1
5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1) (AMPK subunit gamma-1) (AMPKg)

Gene: AAKG1, PRKAG1
Organism: Homo sapiens
Interactions: 145
UniProt ID: P54619

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004691 - cAMP-dependent protein kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

871006

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

19

19

Small-scale

0.989

High

870991

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

15

19

Small-scale

0.985

High

212374

AAKB2
5'-AMP-activated protein kinase subunit beta-2

13

17

Small-scale

0.984

High

871085

AAKB1
5'-AMP-activated protein kinase subunit beta-1

13

16

Small-scale

0.982

High

871080

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

3

17

Small-scale

0.849

High

723960

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.702

High

871055

DCR1C
Protein artemis

4

2

High-throughput

0.694

High

871014

KEAP1
Kelch-like ECH-associated protein 1

3

1

High-throughput

0.675

High

262243

ULK1
Serine/threonine-protein kinase ULK1

3

18

Small-scale

0.667

High

871048

TEKT1
Tektin-1

3

0

High-throughput

0.646

High

871020

AT2B3
Plasma membrane calcium-transporting ATPase 3

3

0

High-throughput

0.638

High

871022

TBB8
Tubulin beta-8 chain

3

0

High-throughput

0.638

High

871046

GLMP
Glycosylated lysosomal membrane protein

3

0

High-throughput

0.638

High

549881

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

2

11

High-throughput

0.628

High

871050

TRI11
E3 ubiquitin-protein ligase TRIM11

2

1

High-throughput

0.628

High

871054

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

2

8

High-throughput

0.628

High

871075

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

2

1

High-throughput

0.611

High

837789

MEOX1
Homeobox protein MOX-1

2

4

High-throughput

0.606

High

871003

KRA11
Keratin-associated protein 1-1

2

9

High-throughput

0.606

High

871060

KR412
Keratin-associated protein 4-12

2

9

High-throughput

0.606

High

871061

KRA98
Keratin-associated protein 9-8

2

9

High-throughput

0.606

High

871062

KRA92
Keratin-associated protein 9-2

2

9

High-throughput

0.606

High

245162

CUTA
Protein CutA

2

0

High-throughput

0.602

High

871044

FNIP1
Folliculin-interacting protein 1

2

1

Small-scale

0.601

High

871004

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

2

0

High-throughput

0.585

High

871025

LTOR1
Ragulator complex protein LAMTOR1

2

0

High-throughput

0.585

High

226966

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

503751

HSP7C
Heat shock cognate 71 kDa protein

2

3

High-throughput

0.584

High

641351

PAX6
Paired box protein Pax-6

2

0

High-throughput

0.580

High

871013

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

2

0

High-throughput

0.580

High

870990

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

14

High-throughput

0.575

High

871077

STIM2
Stromal interaction molecule 2

2

1

High-throughput

0.574

High

871063

KRA42
Keratin-associated protein 4-2

1

9

High-throughput

0.573

High

871068

PKHF2
Pleckstrin homology domain-containing family F member 2

2

3

High-throughput

0.553

High

616912

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

2

High-throughput

0.553

High

230849

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

2

High-throughput

0.536

High

340419

PGK1
Phosphoglycerate kinase 1

1

1

High-throughput

0.536

High

643730

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

2

High-throughput

0.536

High

832263

MCM2
DNA replication licensing factor MCM2

1

5

High-throughput

0.536

High

871002

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

2

High-throughput

0.536

High

871007

NDK3
Nucleoside diphosphate kinase 3

1

3

High-throughput

0.536

High

871009

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

3

High-throughput

0.536

High

871015

SCRIB
Protein scribble homolog

1

2

High-throughput

0.536

High

871016

DSC3
Desmocollin-3

1

1

High-throughput

0.536

High

871058

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.536

High

871084

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

1

High-throughput

0.536

High

606390

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.518

High

871053

AP1S3
AP-1 complex subunit sigma-3

1

0

High-throughput

0.518

High

779087

CCNF
Cyclin-F

1

2

High-throughput

0.515

High

263573

PR40A
Pre-mRNA-processing factor 40 homolog A

1

9

High-throughput

0.515

High

870996

KR105
Keratin-associated protein 10-5

1

9

High-throughput

0.515

High

870998

KR10B
Keratin-associated protein 10-11

1

9

High-throughput

0.515

High

871024

Q6FHY5
MEOX2 protein

1

3

High-throughput

0.515

High

611223

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.513

High

724639

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.513

High

787711

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.513

High

871010

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

871019

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.513

High

871034

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

High-throughput

0.513

High

871066

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

0

High-throughput

0.513

High

871071

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.513

High

871072

SMYD2
N-lysine methyltransferase SMYD2

1

0

High-throughput

0.513

High

871083

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.513

High

275826

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

2

High-throughput

0.508

High

871001

PRKDC
DNA-dependent protein kinase catalytic subunit

1

1

Small-scale

0.501

High

871005

ACACA
Acetyl-CoA carboxylase 1

1

3

Small-scale

0.501

High

871056

CRBN
Protein cereblon

1

1

Small-scale

0.501

High

808426

YAP1
Transcriptional coactivator YAP1

1

5

Small-scale

0.500

High

871073

BABA1
BRISC and BRCA1-A complex member 1

1

0

High-throughput

0.493

High

870993

CASP6
Caspase-6

1

0

High-throughput

0.493

High

871052

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

837882

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.481

High

870994

KR101
Keratin-associated protein 10-1

1

9

High-throughput

0.481

High

870995

KR103
Keratin-associated protein 10-3

1

9

High-throughput

0.481

High

870997

KR109
Keratin-associated protein 10-9

1

9

High-throughput

0.481

High

871039

FLCN
Folliculin

1

0

Small-scale

0.479

High

125278

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

Small-scale

0.479

High

197593

ADA12
Disintegrin and metalloproteinase domain-containing protein 12

1

1

High-throughput

0.479

High

230496

TRAK2
Trafficking kinesin-binding protein 2

1

9

High-throughput

0.479

High

294577

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

297594

RHBT1
Rho-related BTB domain-containing protein 1

1

3

High-throughput

0.479

High

299341

UBXN7
UBX domain-containing protein 7

1

1

High-throughput

0.479

High

487264

ANDR
Androgen receptor

1

3

High-throughput

0.479

High

552330

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

590742

BTF3
Transcription factor BTF3

1

1

High-throughput

0.479

High

622237

ALAT1
Alanine aminotransferase 1

1

1

High-throughput

0.479

High

632226

TNR6
Tumor necrosis factor receptor superfamily member 6

1

1

High-throughput

0.479

High

650774

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

720062

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

823754

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

870992

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

870999

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

871000

RAC1
Ras-related C3 botulinum toxin substrate 1

1

1

High-throughput

0.479

High

871011

CUL3
Cullin-3

1

1

High-throughput

0.479

High

871012

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.479

High

871017

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

871018

NTRK3
NT-3 growth factor receptor

1

2

High-throughput

0.479

High

871021

ZXDC
Zinc finger protein ZXDC

1

1

High-throughput

0.479

High

871028

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

871029

ASB18
Ankyrin repeat and SOCS box protein 18

1

1

High-throughput

0.479

High

871030

TMTC3
Protein O-mannosyl-transferase TMTC3

1

5

High-throughput

0.479

High

871031

AHSA2
Putative activator of 90 kDa heat shock protein ATPase homolog 2

1

2

High-throughput

0.479

High

871032

SYPM
Probable proline--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

871047

FBXW7
F-box/WD repeat-containing protein 7

1

3

High-throughput

0.479

High

871059

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

7

Small-scale

0.479

High

871064

RHBT2
Rho-related BTB domain-containing protein 2

1

4

High-throughput

0.479

High

871065

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

871067

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

871069

RHOF
Rho-related GTP-binding protein RhoF

1

2

High-throughput

0.479

High

871079

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

871082

SOX13
Transcription factor SOX-13

1

1

High-throughput

0.479

High

871086

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

1

High-throughput

0.479

High

196283

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.458

High

262406

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

338181

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

446337

PKHD1
Fibrocystin

1

0

High-throughput

0.458

High

871008

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.458

High

871035

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

0

High-throughput

0.458

High

871043

MORC4
MORC family CW-type zinc finger protein 4

1

0

High-throughput

0.458

High

871057

INT14
Integrator complex subunit 14

1

0

High-throughput

0.458

High

871070

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

871074

SAGE1
Sarcoma antigen 1

1

0

High-throughput

0.458

High

528828

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

Small-scale

0.457

High

306045

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

4

High-throughput

0.445

High

382365

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

1

High-throughput

0.445

High

871026

PKHA7
Pleckstrin homology domain-containing family A member 7

1

6

High-throughput

0.445

High

871036

ULK2
Serine/threonine-protein kinase ULK2

1

15

High-throughput

0.445

High

871078

FNIP2
Folliculin-interacting protein 2

1

1

Small-scale

0.445

High

183361

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

Small-scale

0.438

High

301273

MTCL2
Microtubule cross-linking factor 2

1

9

Small-scale

0.437

High

871042

SFXN5
Sideroflexin-5

1

1

High-throughput

0.437

High

871049

ENTR1
Endosome-associated-trafficking regulator 1

1

1

High-throughput

0.437

High

871051

TMX3
Protein disulfide-isomerase TMX3

1

2

High-throughput

0.437

High

871023

MFS4B
Sodium-dependent glucose transporter 1

3

0

High-throughput

0.347

High

686251

GASR
Gastrin/cholecystokinin type B receptor

2

0

High-throughput

0.328

High

871027

CA094
Uncharacterized protein C1orf94

1

0

High-throughput

0.299

High

871033

GDPD3
Lysophospholipase D GDPD3

1

0

High-throughput

0.279

Low

871038

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

871040

RFESD
Rieske domain-containing protein

1

0

High-throughput

0.279

Low

871045

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

871037

CFA46
Cilia- and flagella-associated protein 46

1

0

High-throughput

0.249

Low

871041

TLC3A
TLC domain-containing protein 3A

1

0

High-throughput

0.249

Low

871076

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.249

Low

871081

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024