HitPredict

Interactor 1: ERF3B (Q8IYD1)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (EC 3.6.5.-) (G1 to S phase transition protein 2 homolog)
Gene: GSPT2

Interactor 2: SRS12 (Q8WXF0)
Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)
Gene: SRSF12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 628 Hs			1 261
+	Hs
		267021 ERF3B_HUMAN (11-628): 0: 686: 100.00		SRS10_HUMAN (1-229): 6.35e-34: 125: 50.00
+	Hs
		1031386 ERF3B_HUMAN (11-628): 0: 686: 100.00		PABP4_HUMAN (2-101): 2.19e-20: 92.1: 18.00
+	Hs
		516584 ERF3B_HUMAN (11-628): 0: 686: 100.00		PABP1_HUMAN (2-101): 3.98e-19: 88.3: 17.00
+	Hs
		545846 ERF3A_HUMAN (130-628): 0: 570: 93.79		PABP4_HUMAN (2-101): 2.19e-20: 92.1: 18.00
+	Hs
		516347 ERF3A_HUMAN (130-628): 0: 570: 93.79		PABP1_HUMAN (2-101): 3.98e-19: 88.3: 17.00
+	Hs
		932920 EF1A1_HUMAN (197-627): 2.18e-176: 510: 37.22		PPIE_HUMAN (10-98): 7.46e-34: 126: 33.71
+	At
		975619 EF1A4_ARATH (197-628): 3.98e-172: 498: 37.24		RBG7_ARATH (5-87): 1.09e-31: 116: 32.53
+	Mm
		914709 EF1A2_MOUSE (197-623): 2.81e-175: 507: 35.75		SRSF3_MOUSE (1-92): 1.68e-23: 95: 32.61
+	Sc
		367579 EF1A_YEAST (197-623): 1.32e-173: 503: 36.20		PABP_YEAST (2-98): 1.48e-20: 92.5: 22.68
+	Sc
		376568 ERF3_YEAST (201-623): 5.98e-164: 486: 56.81		PABP_YEAST (2-98): 1.48e-20: 92.5: 22.68