Interactor 1: XRN1 (Q8IZH2)
5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog)
Gene: XRN1

Interactor 2: RENT1 (Q92900)
Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)
Gene: UPF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 29395067, 14527413, 21145460, 18423202
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000932 - P-body
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005829 - cytosol
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1706
Hs

1 1129
+ Sc
+ Sc
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024