Protein: ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5 trisphosphate receptor) (Inositol 1,4,5-trisphosphate receptor type 1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Protein PCD-6) (Purkinje cell protein 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)

Gene: ITPR1
Organism: Mus musculus
Interactions: 36
UniProt ID: P11881

Gene Ontology (top 5):
GO:0000902 - cell morphogenesis
GO:0001666 - response to hypoxia
GO:0005220 - inositol 1,4,5-trisphosphate-gated calcium channel activity
GO:0005524 - ATP binding
GO:0005635 - nuclear envelope

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

549488

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

14

Small-scale

0.618

High

549517

TRPC4
Short transient receptor potential channel 4

1

13

Small-scale

0.618

High

549505

NCS1
Neuronal calcium sensor 1

1

0

Small-scale

0.586

High

108412

G3X9H5
Huntingtin

2

2

High-throughput

0.584

High

549495

TERA
Transitional endoplasmic reticulum ATPase

2

5

Small-scale

0.584

High

549504

ERLN2
Erlin-2

2

5

Small-scale

0.584

High

549507

RN170
E3 ubiquitin-protein ligase RNF170

2

2

Small-scale

0.584

High

549498

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

3

High-throughput

0.536

High

549515

ERP44
Endoplasmic reticulum resident protein 44

1

1

Small-scale

0.534

High

549500

HDAC4
Histone deacetylase 4

1

0

High-throughput

0.513

High

204387

O35157
Sodium/calcium exchanger 1

1

1

Small-scale

0.500

High

549501

AT1A2
Sodium/potassium-transporting ATPase subunit alpha-2

1

6

Small-scale

0.500

High

549509

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

6

Small-scale

0.500

High

237408

SGMR1
Sigma non-opioid intracellular receptor 1

1

1

Small-scale

0.479

High

549490

HD
Huntingtin

1

2

Small-scale

0.479

High

549492

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.479

High

549493

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

2

Small-scale

0.479

High

549496

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.479

High

549497

CRTC2
CREB-regulated transcription coactivator 2

1

1

Small-scale

0.479

High

549499

GRID2
Glutamate receptor ionotropic, delta-2

1

2

Small-scale

0.479

High

549502

NEB2
Neurabin-2

1

1

High-throughput

0.479

High

549503

LNP
Endoplasmic reticulum junction formation protein lunapark

1

3

High-throughput

0.479

High

549506

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.479

High

549510

Q91UZ1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase

1

2

Small-scale

0.479

High

549511

ERLN1
Erlin-1

1

5

Small-scale

0.479

High

549516

UBE4B
Ubiquitin conjugation factor E4 B

1

1

Small-scale

0.479

High

549518

HOME1
Homer protein homolog 1

1

7

Small-scale

0.479

High

549491

NPL4
Nuclear protein localization protein 4 homolog

1

0

Small-scale

0.458

High

549494

GRM1
Metabotropic glutamate receptor 1

1

0

Small-scale

0.458

High

549508

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.458

High

549513

CNTP2
Contactin-associated protein-like 2

1

0

Small-scale

0.458

High

549489

MET
Hepatocyte growth factor receptor

1

1

High-throughput

0.445

High

398050

CFAD
Complement factor D

1

4

High-throughput

0.437

High

549514

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.426

High

549512

ACON
Aconitate hydratase, mitochondrial

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025