HitPredict

Interactor 1: PELP1 (Q8IZL8)
Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) (Transcription factor HMX3)
Gene: PELP1

Interactor 2: WDR18 (Q9BV38)
WD repeat-containing protein 18
Gene: WDR18

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	0.60	0.760

Property	Details
Experiments	26186194, 28514442, 33961781, 22872859, 36652389, 30021884, 24981860, 37071682, 22190735, 36351913, 21326211
Identification Methods	affinity chromatography technology, cross-linking study, proximity labelling technology, pull down, anti tag coimmunoprecipitation, 3D electron microscopy, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006364 - rRNA processing
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 432
+	Hs
		1224517 PELP1_HUMAN (1-1130): 0: 788: 100.00		SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80
+	Hs
		903360 PELP1_HUMAN (1-1130): 0: 788: 100.00		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Mm
		1118852 PELP1_MOUSE (1-1130): 0: 676: 81.60		WDR18_MOUSE (1-432): 2.39e-85: 268: 83.10
+	Hs
		1056964 MDC1_HUMAN (411-1014): 5.18e-12: 72.8: 11.24		WDR18_HUMAN (1-432): 4.37e-93: 288: 100.00
+	Hs
		903405 CBP_HUMAN (631-1010): 2.14e-28: 126: 16.87		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		1056932 MDC1_HUMAN (411-1014): 5.18e-12: 72.8: 11.24		SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80
+	Hs
		1288258 MINT_HUMAN (731-1119): 1.09e-10: 68.5: 12.18		SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80
+	Mm
		903669 KMT2C_MOUSE (657-1128): 5.97e-12: 72.8: 9.28		WDR5_MOUSE (152-432): 8.2e-55: 186: 14.75
+	Hs
		903172 EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		903374 KMT2C_HUMAN (704-1130): 8.21e-11: 68.9: 9.28		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		1017415 CBP_HUMAN (631-1010): 2.14e-28: 126: 16.87		CDC20_HUMAN (31-153): 3.74e-13: 72.9: 15.52
+	Hs
		1302927 MINT_HUMAN (731-1119): 1.09e-10: 68.5: 12.18		NLE1_HUMAN (1-106): 3.14e-28: 117: 19.63
+	Hs
		1017382 MDC1_HUMAN (411-1014): 5.18e-12: 72.8: 11.24		CDC20_HUMAN (31-153): 3.74e-13: 72.9: 15.52
+	Hs
		998616 EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17		CDC20_HUMAN (31-153): 3.74e-13: 72.9: 15.52