HitPredict

Interactor 1: MEN1 (O00255)
Menin
Gene: MEN1

Interactor 2: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.641

The method score is based on:

Property	Details
Experiments	11526476, 16651450
Identification Methods	affinity chromatography technology, pull down, coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000976 - transcription cis-regulatory region binding GO:0003682 - chromatin binding GO:0005634 - nucleus and 5 others more... GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	610
Hs

1	968

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024