Protein: ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Aging-associated gene 5 protein) (Alkylglycerone-phosphate synthase)

Gene: ADAS, AGPS
Organism: Homo sapiens
Interactions: 140
UniProt ID: O00116

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005777 - peroxisome
GO:0005778 - peroxisomal membrane
GO:0005782 - peroxisomal matrix
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

122447

GNPAT
Dihydroxyacetone phosphate acyltransferase

3

1

Small-scale

0.664

High

122449

PRKN
E3 ubiquitin-protein ligase parkin

3

5

High-throughput

0.640

High

122476

PEX5
Peroxisomal targeting signal 1 receptor

3

1

Small-scale

0.640

High

122438

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

6

High-throughput

0.618

High

122457

CATA
Catalase

3

0

High-throughput

0.616

High

122463

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.611

High

122479

DHB4
Peroxisomal multifunctional enzyme type 2

2

2

High-throughput

0.584

High

122451

PEX14
Peroxisomal membrane protein PEX14

2

0

Small-scale

0.563

High

122460

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

3

High-throughput

0.536

High

122509

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.536

High

122574

SAR1B
Small COPII coat GTPase SAR1B

1

3

High-throughput

0.536

High

122494

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

122521

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

122548

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.513

High

122573

NOP58
Nucleolar protein 58

1

0

High-throughput

0.513

High

122498

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.489

High

122539

HDA11
Histone deacetylase 11

1

1

High-throughput

0.489

High

122440

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

2

High-throughput

0.479

High

122441

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

2

High-throughput

0.479

High

122446

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

1

High-throughput

0.479

High

122452

ECI2
Enoyl-CoA delta isomerase 2

1

1

High-throughput

0.479

High

122454

CE152
Centrosomal protein of 152 kDa

1

1

High-throughput

0.479

High

122455

PCNT
Pericentrin

1

1

High-throughput

0.479

High

122458

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

122459

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

122467

SCP2
Sterol carrier protein 2

1

3

High-throughput

0.479

High

122472

BASI
Basigin

1

1

High-throughput

0.479

High

122474

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.479

High

122477

CDK7
Cyclin-dependent kinase 7

1

2

High-throughput

0.479

High

122478

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

122481

ARL4C
ADP-ribosylation factor-like protein 4C

1

3

High-throughput

0.479

High

122492

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

1

High-throughput

0.479

High

122495

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

122504

GRDN
Girdin

1

1

High-throughput

0.479

High

122507

DEN4C
DENN domain-containing protein 4C

1

2

High-throughput

0.479

High

122508

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

122511

DNMBP
Dynamin-binding protein

1

2

High-throughput

0.479

High

122512

HSDL2
Hydroxysteroid dehydrogenase-like protein 2

1

5

High-throughput

0.479

High

122514

ACD11
Acyl-CoA dehydrogenase family member 11

1

1

High-throughput

0.479

High

122516

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.479

High

122518

LONP2
Lon protease homolog 2, peroxisomal

1

1

High-throughput

0.479

High

122520

CEP97
Centrosomal protein of 97 kDa

1

1

High-throughput

0.479

High

122522

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

3

High-throughput

0.479

High

122523

CNTRB
Centrobin

1

1

High-throughput

0.479

High

122532

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.479

High

122534

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

2

High-throughput

0.479

High

122538

OPTN
Optineurin

1

3

High-throughput

0.479

High

122540

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

3

High-throughput

0.479

High

122542

SPAG5
Sperm-associated antigen 5

1

1

High-throughput

0.479

High

122543

CK5P2
CDK5 regulatory subunit-associated protein 2

1

1

High-throughput

0.479

High

122545

NUD12
NAD-capped RNA hydrolase NUDT12

1

4

High-throughput

0.479

High

122547

DHRS4
Dehydrogenase/reductase SDR family member 4

1

2

High-throughput

0.479

High

122550

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

1

Small-scale

0.479

High

122555

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

122562

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

1

High-throughput

0.479

High

122564

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

122568

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

122570

HACL1
2-hydroxyacyl-CoA lyase 1

1

2

High-throughput

0.479

High

122571

CP131
Centrosomal protein of 131 kDa

1

1

High-throughput

0.479

High

122572

GSTK1
Glutathione S-transferase kappa 1

1

1

High-throughput

0.479

High

61354

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

71672

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.458

High

122442

ACOT8
Acyl-coenzyme A thioesterase 8

1

0

High-throughput

0.458

High

122443

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

122444

PAHX
Phytanoyl-CoA dioxygenase, peroxisomal

1

0

High-throughput

0.458

High

122445

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.458

High

122450

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.458

High

122461

THIK
3-ketoacyl-CoA thiolase, peroxisomal

1

0

High-throughput

0.458

High

122464

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

0

Small-scale

0.458

High

122475

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

122487

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

122488

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

122491

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

122497

FLOT2
Flotillin-2

1

0

High-throughput

0.458

High

122500

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.458

High

122501

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

0

High-throughput

0.458

High

122503

TYSD1
Peroxisomal leader peptide-processing protease

1

0

High-throughput

0.458

High

122510

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

122517

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.458

High

122526

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

122527

ALMS1
Centrosome-associated protein ALMS1

1

0

High-throughput

0.458

High

122530

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

122533

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.458

High

122535

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

0

High-throughput

0.458

High

122544

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.458

High

122549

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

122551

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

122552

WNK1
Serine/threonine-protein kinase WNK1

1

0

High-throughput

0.458

High

122558

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.458

High

122559

PLPL8
Calcium-independent phospholipase A2-gamma

1

0

High-throughput

0.458

High

122560

ANLN
Anillin

1

0

High-throughput

0.458

High

122565

NYNRI
Protein NYNRIN

1

0

High-throughput

0.458

High

122567

NCDN
Neurochondrin

1

0

High-throughput

0.458

High

122468

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.445

High

122480

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.445

High

122483

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

4

High-throughput

0.445

High

122506

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

122448

KIF1C
Kinesin-like protein KIF1C

1

1

High-throughput

0.437

High

122453

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

122465

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

122469

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

122470

EPHA2
Ephrin type-A receptor 2

1

1

High-throughput

0.437

High

122471

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

122485

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

122490

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.437

High

122493

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

122502

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.437

High

122505

PRC2B
Protein PRRC2B

1

1

High-throughput

0.437

High

122513

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

122515

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

122519

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

3

High-throughput

0.437

High

122524

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.437

High

122553

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.437

High

122554

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

122561

STRN4
Striatin-4

1

2

High-throughput

0.437

High

122563

TBA8
Tubulin alpha-8 chain

1

3

High-throughput

0.437

High

122566

WRP73
WD repeat-containing protein WRAP73

1

1

High-throughput

0.437

High

122439

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.426

High

122462

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

122525

S35G3
Solute carrier family 35 member G3

1

0

High-throughput

0.426

High

122529

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.426

High

122556

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

122546

GORS1
Golgi reassembly-stacking protein 1

4

0

High-throughput

0.364

High

122569

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

0

High-throughput

0.279

Low

122456

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

122466

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

122473

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

122482

RBM11
Splicing regulator RBM11

1

0

High-throughput

0.249

Low

122484

F193A
Protein FAM193A

1

0

High-throughput

0.249

Low

122486

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

122489

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

0

Small-scale

0.249

Low

122496

DSG2
Desmoglein-2

1

0

High-throughput

0.249

Low

122499

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

0

High-throughput

0.249

Low

122528

DLG5
Disks large homolog 5

1

0

High-throughput

0.249

Low

122531

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.249

Low

122536

TTC28
Tetratricopeptide repeat protein 28

1

0

High-throughput

0.249

Low

122537

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low

122557

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.249

Low

122541

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025