Interactor 1: ARHG6 (Q8K4I3)
Rho guanine nucleotide exchange factor 6 (Alpha-PIX) (Rac/Cdc42 guanine nucleotide exchange factor 6)
Gene: Arhgef6

Interactor 2: ARHG7 (Q9ES28)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (PAK-interacting exchange factor beta) (p85SPR)
Gene: Arhgef7

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 16959763
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains betaPIX_CC~betaPIX_CC, CH~CH, PH~PH, PH~RhoGEF, RhoGEF~RhoGEF, SH3_2~SH3_2
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0030027 - lamellipodium
GO:0030032 - lamellipodium assembly
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 771
Mm

1 862
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024