HitPredict

Interactor 1: CAND1 (Q8L5Y6)
Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (AtCAND1) (Protein ENHANCER OF TIR1-1 AUXIN RESISTANCE 2) (Protein HEMIVENATA)
Gene: CAND1

Interactor 2: CUL4 (Q8LGH4)
Cullin-4 (AtCUL4)
Gene: CUL4

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.740

Property	Details
Experiments	16844902
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Cullin~TIP120
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1219 At			1 792
+	Hs
		1043440 CAND1_HUMAN (2-1219): 0: 796: 42.73		CUL4B_HUMAN (29-792): 0: 925: 55.95
+	Hs
		1043084 CAND1_HUMAN (2-1219): 0: 796: 42.73		CUL4A_HUMAN (34-792): 0: 915: 55.79
+	Hs
		1041947 CAND1_HUMAN (2-1219): 0: 796: 42.73		CUL3_HUMAN (60-792): 0: 834: 38.63
+	Dm
		1213848 CAND1_DROME (4-1219): 0: 721: 38.83		Q8IP45_DROME (8-792): 0: 863: 35.48
+	Hs
		256749 CAND2_HUMAN (2-1219): 0: 737: 38.14		CUL3_HUMAN (60-792): 0: 834: 38.63
+	At
		1226078 CAND1_ARATH (1-1219): 0: 806: 100.00		CUL1_ARATH (85-792): 0: 759: 32.17
+	Hs
		1041074 CAND1_HUMAN (2-1219): 0: 796: 42.73		CUL1_HUMAN (93-792): 0: 758: 29.37
+	Mm
		1169688 CAND1_MOUSE (2-1219): 0: 795: 42.41		CUL1_MOUSE (93-792): 0: 758: 29.37
+	Hs
		1041383 CAND1_HUMAN (2-1219): 0: 796: 42.73		CUL2_HUMAN (91-792): 0: 717: 26.44
+	Mm
		1169706 CAND2_MOUSE (3-1219): 0: 755: 38.12		CUL1_MOUSE (93-792): 0: 758: 29.37
+	Hs
		256748 CAND2_HUMAN (2-1219): 0: 737: 38.14		CUL1_HUMAN (93-792): 0: 758: 29.37
+	Dm
		1097204 CAND1_DROME (4-1219): 0: 721: 38.83		CUL1_DROME (93-792): 0: 708: 29.15
+	Hs
		1202033 CAND1_HUMAN (2-1219): 0: 796: 42.73		CUL5_HUMAN (92-792): 0: 610: 25.68
+	Ce
		105747 CAND1_CAEEL (1-1219): 0: 591: 28.73		CUL3_CAEEL (75-792): 0: 741: 32.56
+	Ce
		105745 CAND1_CAEEL (1-1219): 0: 591: 28.73		CUL1_CAEEL (80-792): 0: 688: 26.85
+	Ce
		105746 CAND1_CAEEL (1-1219): 0: 591: 28.73		CUL2_CAEEL (63-792): 0: 667: 24.53
+	Ce
		105748 CAND1_CAEEL (1-1219): 0: 591: 28.73		CUL4_CAEEL (6-792): 0: 664: 30.63
+	Ce
		105749 CAND1_CAEEL (1-1219): 0: 591: 28.73		CUL6_CAEEL (93-792): 0: 626: 27.09
+	Ce
		105750 CAND1_CAEEL (1-1219): 0: 591: 28.73		CUL5_CAEEL (92-792): 0: 565: 24.32
+	Sp
		142920 CAND1_SCHPO (8-1219): 2.41e-112: 382: 18.69		CUL1_SCHPO (95-792): 0: 686: 29.89