Protein: SRGP3
SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)

Gene: SRGP3, SRGAP3
Organism: Homo sapiens
Interactions: 50
UniProt ID: O43295

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0030336 - negative regulation of cell migration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

200200

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

3

17

High-throughput

0.861

High

200217

ASPP2
Apoptosis-stimulating of p53 protein 2

3

7

High-throughput

0.861

High

200226

ASPP1
Apoptosis-stimulating of p53 protein 1

3

6

High-throughput

0.861

High

200223

RHG24
Rho GTPase-activating protein 24

2

17

High-throughput

0.767

High

200222

RAPH1
Ras-associated and pleckstrin homology domains-containing protein 1

2

3

High-throughput

0.737

High

200212

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.724

High

181490

CLOCK
Circadian locomoter output cycles protein kaput

3

2

High-throughput

0.667

High

200228

SPAG5
Sperm-associated antigen 5

3

9

High-throughput

0.667

High

200213

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.647

High

200194

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

16

Small-scale

0.618

High

200231

SH3G1
Endophilin-A2

1

17

Small-scale

0.618

High

200232

SH3G2
Endophilin-A1

1

17

Small-scale

0.618

High

63708

CC85C
Coiled-coil domain-containing protein 85C

3

2

High-throughput

0.609

High

200237

ACAD8
Isobutyryl-CoA dehydrogenase, mitochondrial

3

1

High-throughput

0.609

High

200236

TNIK
TRAF2 and NCK-interacting protein kinase

2

8

High-throughput

0.590

High

200234

DISC1
Disrupted in schizophrenia 1 protein

2

2

High-throughput

0.576

High

200204

NKTR
NK-tumor recognition protein

2

2

High-throughput

0.571

High

200239

ROBO1
Roundabout homolog 1

2

4

High-throughput

0.571

High

200203

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

1

High-throughput

0.536

High

200214

VAMP2
Vesicle-associated membrane protein 2

1

1

High-throughput

0.536

High

200215

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

200219

VAMP3
Vesicle-associated membrane protein 3

1

1

High-throughput

0.536

High

200230

KIF2C
Kinesin-like protein KIF2C

1

5

High-throughput

0.536

High

200235

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.536

High

200211

S10AA
Protein S100-A10

1

9

High-throughput

0.515

High

200229

TGS1
Trimethylguanosine synthase

1

0

High-throughput

0.513

High

200208

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

3

Small-scale

0.501

High

200238

MAN1
Inner nuclear membrane protein Man1

1

3

High-throughput

0.489

High

200199

CCD22
Coiled-coil domain-containing protein 22

1

1

High-throughput

0.479

High

200206

SYUA
Alpha-synuclein

1

4

High-throughput

0.479

High

200220

RN123
E3 ubiquitin-protein ligase RNF123

1

7

High-throughput

0.479

High

200221

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

200202

H12
Histone H1.2

1

5

High-throughput

0.470

High

200196

KDM1A
Lysine-specific histone demethylase 1A

1

6

High-throughput

0.464

High

200227

ANM6
Protein arginine N-methyltransferase 6

1

3

High-throughput

0.464

High

200224

DTBP1
Dysbindin

1

0

High-throughput

0.460

High

200225

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

200207

HD
Huntingtin

1

6

High-throughput

0.457

High

200216

FMR1
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.457

High

200205

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.445

High

200218

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

2

High-throughput

0.445

High

200233

ENKD1
Enkurin domain-containing protein 1

1

2

High-throughput

0.439

High

200197

NDK8
Putative nucleoside diphosphate kinase

1

3

High-throughput

0.407

High

200209

SMCA4
Transcription activator BRG1

1

6

Small-scale

0.407

High

200210

PGTB1
Geranylgeranyl transferase type-1 subunit beta

3

0

High-throughput

0.347

High

62843

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.279

Low

200201

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.279

Low

200195

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.265

Low

200198

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024