HitPredict

Interactor 1: CNBL2 (Q8LAS7)
Calcineurin B-like protein 2 (SOS3-like calcium-binding protein 1)
Gene: CBL2

Interactor 2: CIPK9 (Q9MAM1)
CBL-interacting serine/threonine-protein kinase 9 (EC 2.7.11.1) (SNF1-related kinase 3.12) (SOS2-like protein kinase PKS6)
Gene: CIPK9

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.931

Property	Details
Experiments	21798944, 23109687, 25646412, 11402167, 11230129
Identification Methods	two hybrid, fluorescent resonance energy transfer, pull down, protein complementation assay, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	EF-hand_5~NAF, EF-hand_8~NAF, EF-hand_8~Pkinase
Common GO terms	GO:0055075 - potassium ion homeostasis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 226 At			1 447
+	At
		1227181 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKN_ARATH (16-445): 0: 533: 69.04
+	At
		1196432 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKQ_ARATH (7-441): 0: 529: 65.37
+	At
		1103382 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPK3_ARATH (8-447): 0: 525: 64.17
+	At
		1227185 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKO_ARATH (10-446): 1.44e-173: 495: 52.61
+	At
		1227186 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKI_ARATH (2-437): 6.12e-170: 488: 47.02
+	At
		1227191 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKC_ARATH (2-434): 6.24e-170: 487: 47.79
+	At
		1227190 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKG_ARATH (6-444): 8.67e-169: 484: 47.45
+	At
		1227184 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKA_ARATH (11-444): 9.28e-168: 481: 47.14
+	At
		249834 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPK6_ARATH (17-439): 1.13e-167: 480: 52.24
+	At
		187627 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKD_ARATH (2-444): 7.79e-166: 478: 44.47
+	At
		187628 CNBL3_ARATH (1-226): 1.4e-65: 204: 92.04		CIPKD_ARATH (2-444): 7.79e-166: 478: 44.47
+	At
		1227180 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPK1_ARATH (1-442): 1.98e-164: 472: 47.52
+	At
		1227182 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKH_ARATH (14-433): 6.23e-162: 465: 48.10
+	At
		187506 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKB_ARATH (6-431): 2.05e-158: 456: 44.08
+	At
		1227187 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPK2_ARATH (11-447): 2.55e-156: 451: 47.30
+	At
		187507 CNBL3_ARATH (1-226): 1.4e-65: 204: 92.04		CIPKB_ARATH (6-431): 2.05e-158: 456: 44.08
+	At
		1227183 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKL_ARATH (12-435): 1.21e-146: 426: 44.03
+	At
		1227192 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPK4_ARATH (16-389): 5.24e-146: 424: 45.33
+	At
		1227188 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPKE_ARATH (17-412): 3.4e-111: 336: 44.64
+	At
		1227194 CNBL2_ARATH (1-226): 9.74e-68: 209: 100.00		CIPK7_ARATH (8-370): 5.51e-107: 325: 45.88