HitPredict

Interactor 1: CSN5A (Q8LAZ7)
COP9 signalosome complex subunit 5a (Signalosome subunit 5a) (EC 3.4.-.-) (Jun activation domain-binding homolog 1)
Gene: CSN5A

Interactor 2: CSN2 (Q8W207)
COP9 signalosome complex subunit 2 (Signalosome subunit 2) (Protein FUSCA 12)
Gene: CSN2

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	12615944, 15486099
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0009585 - red, far-red light phototransduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 357 At			1 439
+	At
		1258867 CSN5B_ARATH (1-356): 1.45e-134: 389: 85.71		CSN2_ARATH (1-439): 1.66e-121: 362: 100.00
+	Dm
		1277039 CSN5_DROME (6-342): 6.46e-129: 373: 63.80		CSN2_DROME (10-438): 2.24e-113: 341: 59.30
+	Mm
		193516 CSN5_MOUSE (1-338): 4.4e-123: 359: 65.09		CSN2_MOUSE (6-437): 5.1e-117: 350: 61.34
+	Hs
		897288 CSN5_HUMAN (1-338): 6.45e-123: 359: 65.09		CSN2_HUMAN (6-437): 5.1e-117: 350: 61.34
+	Ce
		136314 CSN5_CAEEL (5-354): 7.71e-116: 342: 52.57		CSN2_CAEEL (11-413): 2.46e-99: 307: 53.32
+	An
		1124314 CSN5_EMENI (8-342): 1.28e-108: 322: 51.63		CSN2_EMENI (4-433): 3.95e-105: 322: 48.50
+	Mm
		102340 CSN5_MOUSE (1-338): 4.4e-123: 359: 65.09		G3UXW9_MOUSE (11-438): 1.8e-82: 264: 13.96
+	Mm
		193526 CSN5_MOUSE (1-338): 4.4e-123: 359: 65.09		CSN1_MOUSE (11-438): 2.07e-81: 260: 13.96
+	Hs
		1024199 CSN5_HUMAN (1-338): 6.45e-123: 359: 65.09		CSN1_HUMAN (11-438): 2.1e-79: 255: 13.20
+	Dm
		1358216 CSN5_DROME (6-342): 6.46e-129: 373: 63.80		CSN4_DROME (68-436): 6.5e-69: 226: 16.71
+	Hs
		1272576 CSN5_HUMAN (1-338): 6.45e-123: 359: 65.09		CSN4_HUMAN (67-436): 7.6e-73: 236: 16.17
+	Mm
		193509 CSN5_MOUSE (1-338): 4.4e-123: 359: 65.09		CSN4_MOUSE (65-436): 2.96e-67: 221: 16.08
+	At
		799472 CSN5A_ARATH (1-357): 2.09e-139: 401: 100.00		CSN1_ARATH (227-427): 4.16e-43: 158: 17.59
+	At
		799480 CSN5B_ARATH (1-356): 1.45e-134: 389: 85.71		CSN1_ARATH (227-427): 4.16e-43: 158: 17.59
+	At
		1226047 CSN5A_ARATH (1-357): 2.09e-139: 401: 100.00		CSN4_ARATH (88-436): 6.79e-38: 143: 15.24
+	At
		1226055 CSN5B_ARATH (1-356): 1.45e-134: 389: 85.71		CSN4_ARATH (88-436): 6.79e-38: 143: 15.24
+	Sp
		293445 CSN5_SCHPO (30-336): 3.24e-89: 271: 40.26		CSN2_SCHPO (21-427): 4.69e-81: 258: 45.85
+	Ce
		954225 CSN5_CAEEL (5-354): 7.71e-116: 342: 52.57		CSN1_CAEEL (160-430): 2.47e-25: 110: 14.95
+	Ce
		954226 CSN5_CAEEL (5-354): 7.71e-116: 342: 52.57		CSN4_CAEEL (134-437): 1.17e-23: 104: 15.36
+	An
		1124331 CSN5_EMENI (8-342): 1.28e-108: 322: 51.63		CSN4_EMENI (55-434): 1.45e-25: 109: 14.61