Protein: CXA8
Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70)

Gene: CXA8, GJA8
Organism: Homo sapiens
Interactions: 158
UniProt ID: P48165

Gene Ontology (top 5):
GO:0002088 - lens development in camera-type eye
GO:0005243 - gap junction channel activity
GO:0005886 - plasma membrane
GO:0005922 - connexin complex
GO:0007267 - cell-cell signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

661149

CXB2
Gap junction beta-2 protein

2

16

High-throughput

0.783

High

566966

CXA1
Gap junction alpha-1 protein

1

15

High-throughput

0.691

High

70801

SMIM1
Small integral membrane protein 1

2

1

High-throughput

0.606

High

134366

ACKR2
Atypical chemokine receptor 2

2

8

High-throughput

0.606

High

146023

CLD4
Claudin-4

2

1

High-throughput

0.606

High

146957

C2C2L
Phospholipid transfer protein C2CD2L

2

1

High-throughput

0.606

High

179087

MOT4
Monocarboxylate transporter 4

2

5

High-throughput

0.606

High

207434

LAT
Linker for activation of T-cells family member 1

2

2

High-throughput

0.606

High

306772

VAMP5
Vesicle-associated membrane protein 5

2

11

High-throughput

0.606

High

506104

ITAM
Integrin alpha-M

2

3

High-throughput

0.606

High

583864

CD53
Leukocyte surface antigen CD53

2

5

High-throughput

0.606

High

798181

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

1

High-throughput

0.606

High

816561

BI1
Bax inhibitor 1

2

2

High-throughput

0.606

High

816562

AQP4
Aquaporin-4

2

4

High-throughput

0.606

High

816564

NAC3
Sodium/calcium exchanger 3

2

1

High-throughput

0.606

High

816566

STX1B
Syntaxin-1B

2

7

High-throughput

0.606

High

816570

PMP22
Peripheral myelin protein 22

2

2

High-throughput

0.606

High

816574

MALL
MAL-like protein

2

3

High-throughput

0.606

High

816575

S13A2
Solute carrier family 13 member 2

2

2

High-throughput

0.606

High

816578

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

2

9

High-throughput

0.606

High

816583

TTMP
TPA-induced transmembrane protein

2

2

High-throughput

0.606

High

816585

M4A13
Membrane-spanning 4-domains subfamily A member 13

2

6

High-throughput

0.606

High

816589

TMM65
Transmembrane protein 65

2

1

High-throughput

0.606

High

816594

MOT12
Monocarboxylate transporter 12

2

3

High-throughput

0.606

High

816595

MFSD6
Major facilitator superfamily domain-containing protein 6

2

1

High-throughput

0.606

High

816597

MOT13
Monocarboxylate transporter 13

2

5

High-throughput

0.606

High

816599

TSN33
Tetraspanin-33

2

8

High-throughput

0.606

High

816601

UN93A
Protein unc-93 homolog A

2

2

High-throughput

0.606

High

816603

S13A5
Na(+)/citrate cotransporter

2

2

High-throughput

0.606

High

816608

CLD19
Claudin-19

2

1

High-throughput

0.606

High

816611

CLC1A
C-type lectin domain family 1 member A

2

4

High-throughput

0.606

High

816612

PKR2
Prokineticin receptor 2

2

8

High-throughput

0.606

High

816613

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

6

High-throughput

0.606

High

816614

RL3R2
Relaxin-3 receptor 2

2

9

High-throughput

0.606

High

816615

GP151
G-protein coupled receptor 151

2

7

High-throughput

0.606

High

816621

S38A4
Sodium-coupled neutral amino acid transporter 4

2

7

High-throughput

0.606

High

816628

QRFPR
Pyroglutamylated RF-amide peptide receptor

2

7

High-throughput

0.606

High

816630

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

2

11

High-throughput

0.606

High

816633

P2Y13
P2Y purinoceptor 13

2

11

High-throughput

0.606

High

816639

GPR61
G-protein coupled receptor 61

2

6

High-throughput

0.606

High

816645

S1PR5
Sphingosine 1-phosphate receptor 5

2

9

High-throughput

0.606

High

816650

S39A2
Zinc transporter ZIP2

2

11

High-throughput

0.606

High

816655

S39A9
Zinc transporter ZIP9

2

11

High-throughput

0.606

High

816669

STX8
Syntaxin-8

2

6

High-throughput

0.606

High

526563

CCL4
C-C motif chemokine 4

2

0

High-throughput

0.580

High

816576

SREC
Scavenger receptor class F member 1

2

0

High-throughput

0.580

High

816593

TM182
Transmembrane protein 182

2

0

High-throughput

0.580

High

816596

OTOP2
Proton channel OTOP2

2

0

High-throughput

0.580

High

816600

LAP4B
Lysosomal-associated transmembrane protein 4B

2

0

High-throughput

0.580

High

816629

VATO
V-type proton ATPase 21 kDa proteolipid subunit c''

2

0

High-throughput

0.580

High

816631

MGST2
Microsomal glutathione S-transferase 2

2

0

High-throughput

0.580

High

816638

TM147
BOS complex subunit TMEM147

2

0

High-throughput

0.580

High

816644

FXYD6
FXYD domain-containing ion transport regulator 6

2

0

High-throughput

0.580

High

816656

TM100
Transmembrane protein 100

2

0

High-throughput

0.580

High

816659

S52A1
Solute carrier family 52, riboflavin transporter, member 1

2

0

High-throughput

0.580

High

816665

MARH2
E3 ubiquitin-protein ligase MARCHF2

2

0

High-throughput

0.580

High

816573

ZO1
Tight junction protein ZO-1

1

20

Small-scale

0.561

High

116670

UBXN8
UBX domain-containing protein 8

2

5

High-throughput

0.553

High

218095

MFS11
UNC93-like protein MFSD11

2

2

High-throughput

0.553

High

242231

PRAF2
PRA1 family protein 2

2

3

High-throughput

0.553

High

263193

SC22B
Vesicle-trafficking protein SEC22b

2

9

High-throughput

0.553

High

276308

UPK1B
Uroplakin-1b

2

9

High-throughput

0.553

High

303886

YIF1A
Protein YIF1A

2

1

High-throughput

0.553

High

307693

LERL1
Leptin receptor overlapping transcript-like 1

2

2

High-throughput

0.553

High

309208

APOL3
Apolipoprotein L3

2

5

High-throughput

0.553

High

337394

ABL1
Tyrosine-protein kinase ABL1

2

11

High-throughput

0.553

High

396329

APOD
Apolipoprotein D

2

1

High-throughput

0.553

High

596875

MAL
Myelin and lymphocyte protein

2

3

High-throughput

0.553

High

623608

IBP5
Insulin-like growth factor-binding protein 5

2

3

High-throughput

0.553

High

644388

PPLA
Cardiac phospholamban

2

1

High-throughput

0.553

High

816560

LIPR1
Inactive pancreatic lipase-related protein 1

2

1

High-throughput

0.553

High

816577

SC23A
Protein transport protein Sec23A

2

4

High-throughput

0.553

High

816579

CTXN3
Cortexin-3

2

2

High-throughput

0.553

High

816582

TM128
Transmembrane protein 128

2

2

High-throughput

0.553

High

816587

S35F1
Solute carrier family 35 member F1

2

3

High-throughput

0.553

High

816591

TM107
Transmembrane protein 107

2

1

High-throughput

0.553

High

816592

LAAT1
Lysosomal amino acid transporter 1 homolog

2

2

High-throughput

0.553

High

816598

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

3

High-throughput

0.553

High

816606

S35F6
Solute carrier family 35 member F6

2

4

High-throughput

0.553

High

816607

TM86B
Lysoplasmalogenase TMEM86B

2

5

High-throughput

0.553

High

816610

RN152
E3 ubiquitin-protein ligase RNF152

2

4

High-throughput

0.553

High

816617

GIMA1
GTPase IMAP family member 1

2

2

High-throughput

0.553

High

816618

S39A7
Zinc transporter SLC39A7

2

11

High-throughput

0.553

High

816623

YIPF6
Protein YIPF6

2

2

High-throughput

0.553

High

816624

GIMA5
GTPase IMAP family member 5

2

2

High-throughput

0.553

High

816625

S35A4
Probable UDP-sugar transporter protein SLC35A4

2

1

High-throughput

0.553

High

816626

RUSF1
RUS family member 1

2

1

High-throughput

0.553

High

816627

REEP6
Receptor expression-enhancing protein 6

2

1

High-throughput

0.553

High

816635

SC22C
Vesicle-trafficking protein SEC22c

2

9

High-throughput

0.553

High

816647

TMM60
Transmembrane protein 60

2

2

High-throughput

0.553

High

816651

GP108
Protein GPR108

2

3

High-throughput

0.553

High

816657

S38A7
Sodium-coupled neutral amino acid transporter 7

2

7

High-throughput

0.553

High

816666

PGAP2
Post-GPI attachment to proteins factor 2

2

2

High-throughput

0.553

High

178430

STX7
Syntaxin-7

1

7

High-throughput

0.536

High

507909

FGFR1
Fibroblast growth factor receptor 1

1

9

High-throughput

0.536

High

816559

CTR2
Cationic amino acid transporter 2

1

6

High-throughput

0.536

High

816567

STXB1
Syntaxin-binding protein 1

1

9

High-throughput

0.536

High

816604

LRC8A
Volume-regulated anion channel subunit LRRC8A

1

6

High-throughput

0.536

High

816632

S29A1
Equilibrative nucleoside transporter 1

1

3

High-throughput

0.536

High

816640

TTYH3
Protein tweety homolog 3

1

2

High-throughput

0.536

High

816652

GPC5C
G-protein coupled receptor family C group 5 member C

1

4

High-throughput

0.536

High

816663

GPC5B
G-protein coupled receptor family C group 5 member B

1

4

High-throughput

0.536

High

816590

OLFM4
Olfactomedin-4

1

2

High-throughput

0.515

High

816641

THS7B
Thrombospondin type-1 domain-containing protein 7B

1

4

High-throughput

0.515

High

311154

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

High-throughput

0.513

High

197479

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

1

1

High-throughput

0.489

High

371156

NU4M
NADH-ubiquinone oxidoreductase chain 4

1

2

High-throughput

0.489

High

452207

HMOX1
Heme oxygenase 1

1

1

High-throughput

0.489

High

816572

PSME1
Proteasome activator complex subunit 1

1

3

High-throughput

0.489

High

816602

STX12
Syntaxin-12

1

7

High-throughput

0.489

High

816619

FAM3C
Protein FAM3C

1

3

High-throughput

0.489

High

816648

SNX25
Sorting nexin-25

1

3

High-throughput

0.489

High

816668

PSME2
Proteasome activator complex subunit 2

1

3

High-throughput

0.489

High

816671

MAN1
Inner nuclear membrane protein Man1

1

2

High-throughput

0.489

High

310546

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

5

High-throughput

0.481

High

816581

SGMR2
Sigma intracellular receptor 2

1

2

High-throughput

0.481

High

816662

NINJ2
Ninjurin-2

1

1

High-throughput

0.481

High

816622

AP2M1
AP-2 complex subunit mu

1

0

High-throughput

0.480

High

816565

MYPR
Myelin proteolipid protein

1

0

High-throughput

0.460

High

816646

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.460

High

816654

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

2

High-throughput

0.439

High

816642

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

6

Small-scale

0.437

High

49406

TMM72
Transmembrane protein 72

2

0

High-throughput

0.316

High

361566

APOA2
Apolipoprotein A-II

2

0

High-throughput

0.316

High

514355

PSPC
Surfactant protein C

2

0

High-throughput

0.316

High

740896

FDFT
Squalene synthase

2

0

High-throughput

0.316

High

816569

CP4F2
Cytochrome P450 4F2

2

0

High-throughput

0.316

High

816571

GUC2A
Guanylin

2

0

High-throughput

0.316

High

816580

ORML2
ORM1-like protein 2

2

0

High-throughput

0.316

High

816584

DB121
Beta-defensin 121

2

0

High-throughput

0.316

High

816586

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

2

0

High-throughput

0.316

High

816588

TMM42
Transmembrane protein 42

2

0

High-throughput

0.316

High

816605

S66A2
Solute carrier family 66 member 2

2

0

High-throughput

0.316

High

816609

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

2

0

High-throughput

0.316

High

816616

TM239
Transmembrane protein 239

2

0

High-throughput

0.316

High

816634

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.316

High

816636

TM121
Transmembrane protein 121

2

0

High-throughput

0.316

High

816637

TM243
Transmembrane protein 243

2

0

High-throughput

0.316

High

816643

TWSG1
Twisted gastrulation protein homolog 1

2

0

High-throughput

0.316

High

816649

CIA2A
Cytosolic iron-sulfur assembly component 2A

2

0

High-throughput

0.316

High

816653

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

2

0

High-throughput

0.316

High

816658

TM45A
Transmembrane protein 45A

2

0

High-throughput

0.316

High

816660

TM242
Transmembrane protein 242

2

0

High-throughput

0.316

High

816661

CLN6
Ceroid-lipofuscinosis neuronal protein 6

2

0

High-throughput

0.316

High

816664

CC167
Coiled-coil domain-containing protein 167

2

0

High-throughput

0.316

High

816670

DOLK
Dolichol kinase

2

0

High-throughput

0.316

High

816672

INSI2
Insulin-induced gene 2 protein

2

0

High-throughput

0.316

High

210546

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

1

0

High-throughput

0.279

Low

210643

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

0

High-throughput

0.279

Low

304749

NDUB6
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6

1

0

High-throughput

0.279

Low

306514

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

0

High-throughput

0.279

Low

816563

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

0

High-throughput

0.279

Low

816568

SELT
Thioredoxin reductase-like selenoprotein T

1

0

High-throughput

0.279

Low

816620

DNSL2
Deoxyribonuclease-1-like 2

1

0

High-throughput

0.279

Low

816667

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

0

High-throughput

0.279

Low

816673

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.279

Low

329485

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

778997

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024