Interactor 1: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR
Interactor 2: AKTS1 (Q96B36)
Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate)
Gene: AKT1S1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.763 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18030348, 18570873, 17277771, 25940091, 20169205, 17386266, 33230243, 33852892, 35271311, 19446321, 17517883, 17604271, 18215133, 23953116 |
| Identification Methods | affinity chromatography technology, unspecified method, anti tag coimmunoprecipitation, in-gel kinase assay, pull down, far western blotting, protein kinase assay, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, phosphorylation reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030291 - protein serine/threonine kinase inhibitor activity GO:0031931 - TORC1 complex |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
